Clofazimine is an antimicrobial agent primarily used to treat leprosy (Hansen's disease). It works by inhibiting the growth of Mycobacterium leprae, the bacteria responsible for leprosy. Additionally, clofazimine has shown efficacy in treating certain drug-resistant tuberculosis cases.
Precautions of Hansepran Capsule:
- Gastrointestinal Risks: Clofazimine can cause severe stomach or bowel problems, including obstruction or bleeding.
- QT Prolongation: It may affect heart rhythm; caution is advised for patients with cardiac conditions.
- Psychological Effects: Skin discoloration may lead to depression or suicidal thoughts.
Uses of Hansepran Capsule:
- Leprosy Treatment: Clofazimine is a key component in multi-drug therapy for lepromatous leprosy, including cases resistant to dapsone.
- Erythema Nodosum Leprosum (ENL): It helps manage ENL, a severe inflammatory complication of leprosy.
Side Effects of Hansepran Capsule:
Common side effects include:
- Skin Discoloration: A reddish-brown pigmentation of the skin occurs in 75-100% of patients.
- Gastrointestinal Issues: Such as abdominal pain, diarrhea, nausea, and vomiting.
- Dry Skin and Eyes: Patients may experience dryness, burning, or itching.
FAQs of Hansepran Capsule:
1. Can I take clofazimine during pregnancy?
The safety of clofazimine during pregnancy is unclear. Consult your healthcare provider.
2. How should I store clofazimine capsules?
Store at room temperature, away from moisture and direct light.
3. What should I do if I miss a dose?
Take the missed dose as soon as you remember, unless it's almost time for the next one. Do not double up doses.
Interactions of Hansepran Capsule:
Clofazimine has known interactions with several drugs:
- Severe Interactions: With medications like clarithromycin and ceritinib.
- Moderate Interactions: Includes drugs such as hydroxychloroquine and ribociclib.
- Minor Interactions: Notably with rifampin.
| Manufacturer | : | Abbott |
| Equivalent Brand | : | Clofazimine |
| Generic Search | : |
