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  1. Generic: Deferasirox
    Equivalent Brand: Exjade
    30 Tablet/s
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Thalassemia is a group of genetic blood disorders characterized by abnormalities in hemoglobin, the protein responsible for carrying oxygen in red blood cells. Individuals with thalassemia produce fewer healthy red blood cells and less hemoglobin than normal, leading to anemia.

Types of Thalassemia:

1. Alpha Thalassemia:

In alpha thalassemia, there is a reduced production of alpha globin chains, which are components of hemoglobin. Severity varies, and individuals may experience mild to severe anemia.

2. Beta Thalassemia:

Beta thalassemia involves reduced production of beta globin chains. The severity of symptoms ranges from mild to severe. Individuals with beta thalassemia major may require regular blood transfusions.


Thalassemia is inherited through autosomal recessive genes. Individuals inherit one affected gene from each parent. Carriers (individuals with one affected gene) usually do not show symptoms but can pass the gene to their children.


  • Anemia: Reduced hemoglobin and red blood cell production lead to anemia, resulting in fatigue, weakness, and pallor.
  • Jaundice: An increased breakdown of red blood cells can cause jaundice, leading to yellowing of the skin and eyes.
  • Enlarged Spleen and Liver: The body may attempt to compensate for the decreased red blood cells by increasing the size of the spleen and liver.
  • Facial Bone Deformities (in severe cases): In individuals with severe thalassemia, particularly beta thalassemia major, facial bone deformities may occur due to abnormal bone marrow expansion.
  • Growth and Developmental Delays (in severe cases): Children with severe thalassemia may experience delays in growth and development.


  • Blood Transfusions: Individuals with moderate to severe thalassemia may require regular blood transfusions to maintain adequate hemoglobin levels.
  • Chelation Therapy: Blood transfusions can lead to iron overload in the body. Chelation therapy helps remove excess iron to prevent complications.
  • Bone Marrow Transplant: For severe cases, especially in children with beta thalassemia major, a bone marrow transplant may be considered.
  • Folic Acid Supplements: Folic acid supplements are often prescribed to support red blood cell production.
  • Genetic Counseling: Individuals and families with thalassemia may benefit from genetic counseling to understand the risk of passing the condition to future generations.


Genetic testing and counseling can help identify carriers of thalassemia and guide family planning decisions. Prenatal testing is available to detect thalassemia in the fetus during pregnancy.


The prognosis for individuals with thalassemia varies based on the type and severity of the condition. With appropriate medical management, many individuals with thalassemia can lead healthy lives.

It's essential for individuals with thalassemia to work closely with healthcare providers to develop a personalized treatment plan and manage the condition effectively. Early diagnosis and intervention contribute to better outcomes for individuals with thalassemia.

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