Product Overview

Lesuride Injection (Levosulpiride) is a sterile injectable formulation containing Levosulpiride, a selective dopamine D2 receptor antagonist primarily used to manage gastrointestinal motility disorders and related digestive conditions. It is commonly administered in clinical settings when rapid symptom relief or injectable therapy is required.

The medication enhances gastrointestinal motility by improving coordinated muscle contractions in the digestive tract while also helping reduce symptoms such as nausea and vomiting. Due to its prokinetic and antiemetic properties, Lesuride Injection is widely utilized under medical supervision for patients experiencing delayed gastric emptying and associated gastrointestinal discomfort.

Pharmacological Profile

Parameter	Details
Active Ingredient	Levosulpiride
Drug Class	Prokinetic Agent / Dopamine D2 Receptor Antagonist
Dosage Form	Injection
Primary Indications	Gastrointestinal motility disorders, nausea, vomiting
Route of Administration	Intramuscular (IM) or Intravenous (IV), as prescribed

Mechanism Insights (How It Works)

Dopamine Receptor Blockade
Levosulpiride selectively blocks dopamine D2 receptors, reducing dopamine-mediated inhibition of gastrointestinal movement and promoting normal digestive function.
Enhanced Gastrointestinal Motility
The medication stimulates coordinated contractions of the stomach and intestines, helping accelerate gastric emptying and improve food transit through the digestive tract.
Antiemetic Action
By inhibiting dopamine receptors involved in the vomiting reflex, Lesuride Injection helps reduce nausea and vomiting associated with gastrointestinal disorders.

Administration Guidelines

Administer only under the supervision of a qualified healthcare professional.
Follow the prescribed dosage and administration route.
Injection may be given intramuscularly or intravenously as directed by the physician.
Complete the recommended treatment course for optimal therapeutic outcomes.
Do not self-administer unless specifically instructed by a healthcare provider.

Clinical Considerations

Commonly used when oral medication is not suitable or rapid symptom control is required.
Supports improved gastric emptying in patients with gastrointestinal motility disorders.
Frequently prescribed for the management of nausea and vomiting associated with digestive conditions.
Dosage and treatment duration should be individualized based on the patient's clinical condition and physician's assessment.
Patients should remain under medical supervision during injectable therapy to ensure safe and effective treatment.

Precautions:

Lesuride Injection (Levosulpiride) should be administered with caution under the supervision of a qualified healthcare professional. It is important to follow the prescribed dosage and monitor patients with certain medical conditions to ensure safe and effective treatment.

General Precautions

Use only under the guidance of a healthcare professional
Do not self-administer unless instructed by your doctor
Follow the recommended dosage and treatment duration
Inform your doctor about all current medications and medical conditions
Avoid alcohol if advised, as it may increase drowsiness

Kidney & Liver Function Considerations

Use with caution in patients with kidney or liver impairment
Dose adjustments may be required based on the severity of the condition
Regular monitoring may be recommended during prolonged treatment
Inform your doctor if you experience unusual fatigue, yellowing of the skin, or dark urine

Pregnancy & Breastfeeding

Use during pregnancy only if clearly recommended by a healthcare provider
Inform your doctor if you are pregnant or planning to become pregnant
Breastfeeding mothers should consult their doctor before receiving the injection
The benefits and potential risks should be carefully evaluated before use

Neurological & Cardiac Considerations

Use cautiously in patients with a history of epilepsy or seizures
May cause dizziness or drowsiness; avoid driving or operating machinery if affected
Caution is advised in patients with heart rhythm disorders or prolonged QT interval
Seek immediate medical attention if you experience palpitations, fainting, or severe dizziness

Usage

General Usage Information

Lesuride Injection (Levosulpiride) is used as part of a prescribed treatment plan to manage gastrointestinal disorders by improving stomach and intestinal motility. It helps relieve symptoms such as nausea, vomiting, bloating, indigestion, and delayed gastric emptying when administered under the supervision of a healthcare professional.

Key Usage Points

✔ Use the injection only as prescribed by a healthcare professional
✔ Administered by a doctor or qualified healthcare provider
✔ Follow the recommended dosage and treatment schedule carefully
✔ Do not stop the treatment without medical advice
✔ Inform your doctor about any existing medical conditions or medications before use

Uses

Lesuride Injection is commonly used for the treatment of gastrointestinal motility disorders, nausea, vomiting, diabetic gastroparesis, functional dyspepsia, and related digestive conditions requiring injectable therapy.

How to Use

Lesuride Injection is administered by a healthcare professional through the prescribed route (intramuscular or intravenous).
The dosage and duration depend on the patient's age, medical condition, and response to treatment.
Do not self-administer unless specifically instructed by your healthcare provider.
Attend all scheduled doses to achieve the best therapeutic results.
Follow your doctor's instructions throughout the treatment course for maximum effectiveness.

Side Effects

General Safety Information

Lesuride Injection (Levosulpiride) is generally used under medical supervision and is considered effective when administered as prescribed. Most side effects are mild to moderate, but they can vary depending on the patient’s condition, dosage, and duration of treatment.

Common Side Effects

✔ Drowsiness or sleepiness
✔ Dizziness
✔ Nausea
✔ Dry mouth
✔ Fatigue or weakness
✔ Mild gastrointestinal discomfort

These effects are usually temporary and often improve as the body adjusts to the medicine.

Serious Side Effects (Rare but Important)

⚠ Seek immediate medical attention if you experience:

Signs of abnormal muscle movements (tremors, stiffness, restlessness)
Hormonal changes (breast tenderness, milk discharge, menstrual irregularities)
Severe dizziness or fainting
Allergic reactions (rash, itching, swelling)
Irregular heartbeat or chest discomfort
Mood changes or confusion

Risk Factors & Monitoring

Higher risk in elderly patients or those with neurological conditions
Long-term use may increase the risk of movement-related side effects
May affect prolactin levels, requiring medical monitoring in prolonged therapy
Doctors may recommend regular follow-ups depending on treatment duration and dose

FAQs

What is Lesuride Injection used for?
Lesuride Injection (Levosulpiride) is used to treat nausea, vomiting, indigestion, and certain gastrointestinal motility disorders. It helps improve stomach movement and relieves symptoms like bloating and discomfort.

How does Lesuride Injection work in the body?
It works by blocking dopamine receptors in the brain and gut, which helps control nausea and vomiting while also improving gastric emptying and digestive movement.

Can Lesuride Injection be given to children?
It is generally not recommended for children unless specifically prescribed by a doctor. Use in pediatric patients should only be done under strict medical supervision.

How should I take Lesuride Injection?
Lesuride Injection should be administered by a qualified healthcare professional, usually via intramuscular or intravenous route, depending on the doctor’s prescription. It should not be self-administered.

Interactions

General Interaction Overview

Lesuride Injection (Levosulpiride) may interact with several medicines that affect the central nervous system, gastrointestinal motility, or heart rhythm. These interactions can change how the medicine works or increase the risk of side effects such as drowsiness, movement-related symptoms, or cardiac issues. It is important to inform your healthcare provider about all medicines you are using.

Commonly Reported Interactions

Dopamine-related medicines (e.g., levodopa, bromocriptine) may have reduced effectiveness because Levosulpiride blocks dopamine receptors.
Antipsychotic drugs can increase the risk of side effects like rigidity, tremors, or other extrapyramidal symptoms.
CNS depressants such as alcohol, benzodiazepines, or sleeping pills may increase drowsiness and sedation.
Anticholinergic medications may reduce the digestive (prokinetic) effect of Levosulpiride.
QT-prolonging medicines (certain antibiotics or antiarrhythmics) may increase the risk of irregular heart rhythm when used together.
Antihypertensive drugs may enhance the risk of dizziness or low blood pressure in some patients.

Always inform your doctor about all prescription, over-the-counter, and herbal medicines you are taking to avoid unwanted interactions and ensure safe treatment.

More Information Demo
Manufacturer	:	Sun Pharmaceutical Industries Ltd
Equivalent Brand	:
Generic Search	:	Levosulpiride

Package	QTY	Price	Add To Cart
10 Injection/s		$27.33
30 Injection/s		$82.00
60 Injection/s		$164.00

Lesuride Injection (Levosulpiride): Prokinetic Injection | For Gastrointestinal Motility Disorders, Nausea, Vomiting & Functional Dyspepsia Management