Propylthiouracil (PTU) is a medication primarily used to manage hyperthyroidism, including conditions like Graves' disease and toxic goiter. It functions by inhibiting the production of thyroid hormones and blocking the conversion of thyroxine (T4) to triiodothyronine (T3), thereby helping to normalize thyroid activity.
PTU Tablet of Precautions:
Before taking PTU:
- Allergies: Inform your doctor of any known allergies to PTU or other medications.
- Medical History: Disclose any history of liver disease, blood disorders, or immune system issues.
- Pregnancy and Breastfeeding: PTU may harm an unborn baby and passes into breast milk. Discuss risks and benefits with your doctor.
- Regular Monitoring: Regular blood tests are necessary to monitor liver function and blood cell counts during treatment.
PTU Tablet of Uses:
PTU is prescribed for:
- Hyperthyroidism: Overactive thyroid gland.
- Graves' Disease: An autoimmune disorder leading to hyperthyroidism.
- Toxic Goiter: Enlarged thyroid gland producing excess hormones.
It is sometimes administered before thyroid surgery or radioactive iodine treatment to control symptoms.
PTU Tablet of Side Effects:
While PTU is effective, it may cause side effects, ranging from mild to severe:
Common Side Effects:
- Nausea
- Vomiting
- Stomach pain
- Headache
- Dizziness
- Change in taste
- Drowsiness
- Hair loss
- Skin rash or itching
- Muscle or joint pain
- Numbness or tingling
- Upset stomach
- Loss of taste
- Skin pigmentation changes
- Swelling
- Heartburn
- Allergic reactions
- Hair whitening
Serious Side Effects:
- Liver Damage: PTU has been associated with severe liver injury, including liver failure and death. Symptoms include yellowing of the skin or eyes (jaundice), dark urine, persistent nausea or vomiting, and severe fatigue.
- Agranulocytosis: A dangerous drop in white blood cells, leading to increased infection risk. Symptoms include fever, sore throat, and chills.
- Aplastic Anemia: A condition where the body stops producing enough new blood cells, causing fatigue and higher infection risk.
- Bleeding or Bruising: Unusual bleeding or bruising may occur.
Seek immediate medical attention if you experience any serious side effects.
PTU Tablet of FAQs:
- How should I take PTU?
Take PTU exactly as prescribed by your doctor, typically in divided doses throughout the day. Consistency is key for effectiveness.
- What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it's near the time for the next dose, skip the missed dose. Do not double up.
- Can I consume alcohol while on PTU?
It's advisable to limit alcohol intake, as both PTU and alcohol can affect liver function.
- How long will I need to take PTU?
Treatment duration varies; some may require PTU for several months to years, depending on their condition and response.
- Are there dietary restrictions while taking PTU?
No specific dietary restrictions, but maintaining a balanced diet supports overall health.
PTU Tablet of Interactions:
PTU can interact with other medications, potentially altering its effectiveness or increasing side effect risks:
- Anticoagulants: PTU may enhance the effect of blood thinners, increasing bleeding risk.
- Beta-Blockers: Used together to manage hyperthyroid symptoms; dosage adjustments may be necessary.
- Theophylline: PTU may increase theophylline levels, used for respiratory diseases.
Always inform your healthcare provider of all medications and supplements you're taking.
| Manufacturer | : | Macleods Pharmaceuticals Pvt Ltd |
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