Aprezo Tablet (Apremilast)
manage chronic inflammatory and autoimmune disorders, especially psoriasis and psoriatic arthritis. It works by selectively inhibiting the PDE4 (phosphodiesterase-4) enzyme, which plays a key role in regulating the body’s inflammatory response. By lowering the production of pro-inflammatory cytokines and increasing anti-inflammatory signals, Aprezo helps restore balance to the immune system.
This results in a significant reduction of symptoms such as redness, itching, scaling of the skin, joint pain, stiffness, and swelling. Patients often experience improvement not only in skin lesions but also in mobility and overall quality of life.
Aprezo is taken orally and is typically introduced through a gradual dose-titration schedule, especially during the first 5–6 days of treatment. This slow increase in dosage helps the body adjust to the medication and reduces the chances of common side effects such as nausea or diarrhea.
Introduction Of Aprezo Tablet (Apremilast)
Aprezo Tablet contains Apremilast, an oral medication used to treat inflammatory autoimmune conditions. It works by inhibiting an enzyme called PDE4 (Phosphodiesterase-4), which helps reduce inflammation in the body.
Aprezo is commonly prescribed for psoriasis and psoriatic arthritis.
Precautions Of Aprezo Tablet
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Not recommended in severe kidney disease without dose adjustment.
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Use cautiously if you have depression or mood disorders, as mood changes can occur.
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Inform your doctor if you experience unexplained weight loss.
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Not recommended during pregnancy or breastfeeding unless advised.
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Keep yourself hydrated, especially if diarrhea occurs.
Uses of Aprezo Tablet
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Moderate to severe plaque psoriasis
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Psoriatic arthritis
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Reducing skin inflammation, itching, and redness
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Improving joint mobility and stiffness
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Preventing flare-ups of autoimmune symptoms
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Improving overall quality of life in chronic inflammatory conditions
Side Effects of Aprezo Tablet
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Diarrhea
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Nausea
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Vomiting
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Headache
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Loss of appetite
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Unintentional weight loss
FAQ of Aprezo Tablet
1. What is Aprezo used for?
It is used to treat psoriasis and psoriatic arthritis.
2. When will I start seeing results?
Improvements usually appear within 2–12 weeks.
3. Can I take Aprezo with food?
Yes, it can be taken with or without food.
4. Does Aprezo cause weight loss?
Yes, weight loss is a known side effect.
5. Is Aprezo a steroid?
No, it is a PDE4 inhibitor, not a steroid.
6. Do I need blood tests while taking Aprezo?
Usually no routine blood monitoring is required.
7. Can I stop taking it suddenly?
Do not stop without consulting your doctor.
Interactions of Aprezo Tablet
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Aprezo may interact with strong CYP450 enzyme-inducing medicines, which can reduce its effectiveness.
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Avoid using it with Rifampicin, Carbamazepine, Phenytoin, Phenobarbital, and St. John’s Wort, as these can lower Apremilast levels in the body.
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Using Aprezo along with other immunosuppressant or biologic medicines may increase the risk of infections and should be taken only under medical supervision.
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Medicines used for depression, anxiety, or mood-related disorders may interact with Aprezo and increase the risk of mood changes.
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If you are taking medicines that affect kidney function, dose adjustments may be necessary.
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No major food interactions are reported, but alcohol should be taken in moderation as it may increase dehydration or mood-related side effects.
| Manufacturer | : | Glenmark Pharmaceuticals Ltd |
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