Pirox DT Tablet (Piroxicam)
Piroxicam, often marketed under brand names like Mobicam DT and Feldene, is a nonsteroidal anti-inflammatory drug (NSAID) used to alleviate pain and reduce inflammation.
Introduction of Mobicam Tablet DT (Piroxicam)
Piroxicam, often marketed under brand names like Mobicam DT and Feldene, is a nonsteroidal anti-inflammatory drug (NSAID) used to alleviate pain and reduce inflammation. Piroxicam belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). Its mechanism of action involves inhibiting enzymes called cyclooxygenases (COX), specifically COX-1 and COX-2. These enzymes play a crucial role in the synthesis of prostaglandins, which are hormone-like substances that mediate inflammation, pain, and fever in the body.
Inhibition of COX-1 and COX-2:
Piroxicam works by inhibiting both COX-1 and COX-2 enzymes. COX-1 is involved in the production of prostaglandins that help maintain normal physiological functions, including protecting the stomach lining and supporting kidney function. COX-2, on the other hand, is primarily responsible for producing prostaglandins that promote inflammation, pain, and fever in response to injury or inflammation.
Reduction of Prostaglandins:
By inhibiting COX-1 and COX-2, Piroxicam reduces the production of prostaglandins. This reduction leads to a decrease in the inflammatory response, resulting in diminished pain, swelling, and fever. It is particularly effective in conditions where inflammation is a prominent component, such as Arthritis and other inflammatory disorders.
Analgesic Effect:
Piroxicam's ability to decrease prostaglandin production also contributes to its analgesic (pain-relieving) effect. Prostaglandins sensitize pain receptors, making them more responsive to pain stimuli. By lowering prostaglandin levels, Piroxicam helps Pain-Relief by reducing the sensitization of pain receptors.
Anti-Inflammatory Action:
Inflammatory responses are characterized by the release of various chemicals that promote swelling, redness, and pain. Piroxicam's inhibition of COX enzymes and subsequent reduction in prostaglandin production leads to a decrease in these inflammatory markers. This helps control the excessive inflammation associated with conditions like arthritis.
Fever Reduction:
Piroxicam's impact on COX-2 also plays a role in reducing fever. During infections or other conditions that trigger a fever, the body produces prostaglandins that raise the body's temperature. By inhibiting COX-2 and reducing prostaglandin production, Piroxicam helps bring down elevated body temperatures.
Piroxicam Dosage Information:
Standard Dosage: The typical initial adult dose of Piroxicam tablets is 20 mg per day, taken orally as a single dose or divided into two smaller doses.
Missed Dose: If a dose is missed, it should be taken as soon as remembered. However, if it is close to the time for the next dose, the missed dose should be skipped to avoid doubling up.
Overdose: Exceeding the recommended dose can lead to serious health risks. Overdose symptoms may include nausea, vomiting, stomach pain, drowsiness, and even more severe complications. In case of overdose, seek immediate medical attention.
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Essential Safety Advice To Follow When Using Mobicam Tablet DT (Piroxicam)
Allergies and Sensitivities: Individuals with known hypersensitivity to NSAIDs should avoid Piroxicam tablets/Feldene.
Medical Conditions: People with a history of gastrointestinal disorders, heart disease, high blood pressure, kidney problems, and bleeding disorders should use Piroxicam cautiously.
Pregnancy and Lactation: Pregnant and breastfeeding individuals should consult their healthcare provider before using Piroxicam, as it can have adverse effects on the fetus or infant.
Elderly Population: The elderly are more susceptible to side effects, especially gastrointestinal bleeding, and should use Piroxicam with caution.
Concomitant Medications: Inform your healthcare provider about all medications, including over-the-counter drugs and supplements, to prevent potential interactions.
Piroxicam for Over-the-Counter:
Piroxicam, a potent NSAID, is not available over the counter due to its potential side effects and interactions. Its prescription-only status ensures that individuals receive proper medical guidance and supervision when using this medication to manage pain, inflammation, and fever.
Some Of The Specific Indications For Feldene/Piroxicam Tablet Include
Pain Management: Piroxicam tablets are commonly prescribed to manage mild to moderate pain, including musculoskeletal pain, dental pain, and menstrual pain.
Inflammatory Conditions: The drug is effective in reducing inflammation in various conditions such as arthritis, Osteoarthritis, and Rheumatoid arthritis.
Fever Reduction: Piroxicam can help lower fever in individuals with fever-related conditions.
Ankylosing Spondylitis: It is used as a part of the treatment plan for ankylosing spondylitis, a type of inflammatory arthritis affecting the spine.
Actinic Keratosis: Piroxicam in gel form is also utilized topically to treat actinic keratosis, a pre-cancerous skin condition caused by prolonged sun exposure.
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Some Of The Secondary Effects Of Mobicam Tablet DT (Piroxicam)
Gastrointestinal Issues: Piroxicam can lead to stomach discomfort, heartburn, and in some cases, gastrointestinal bleeding or ulcers.
Cardiovascular Effects: Long-term or high-dose use may increase the risk of cardiovascular events such as heart attack or stroke.
Renal Effects: NSAIDs like Piroxicam can adversely affect kidney function, causing fluid retention and potential kidney problems.
Allergic Reactions: Some individuals may experience allergic reactions, including skin rash, itching, and swelling.
Central Nervous System: Piroxicam can rarely cause dizziness, headache, and nervousness.
Answers To Common Inquiries About Piroxicam Tablets
Q1. What Is The Recommended Dosage For Piroxicam Tablets?
The usual starting dose for Piroxicam is 20 mg daily, taken as a single dose or divided into two smaller doses. However, your healthcare provider will determine the appropriate dosage based on your medical condition and response to treatment.
Q2. Can Piroxicam Be Used To Treat Skin Conditions?
Yes, Piroxicam is available in gel form and can be used topically to treat actinic keratosis, a pre-cancerous skin condition caused by sun exposure. It's important to follow your doctor's instructions for applying the gel and monitor for any adverse reactions.
Q3. What Precautions Should Pregnant Individuals Take With Piroxicam?
Pregnant individuals should consult their healthcare provider before using Piroxicam. This medication should be avoided, especially in the last trimester, as it may pose risks to the fetus. Safer alternatives for pain relief should be discussed with the doctor.
Q4. How Does Piroxicam Differ From Other Pain Relievers Like Opioids?
Piroxicam belongs to the NSAID class, addressing pain and inflammation by inhibiting prostaglandin production. Unlike opioids, which work on the brain's pain receptors, Piroxicam targets the root cause of pain without causing the same potential for dependence or central nervous system effects.
Q5. Can Piroxicam Be Taken With Herbal Supplements?
It's advisable to consult your healthcare provider before taking Piroxicam alongside herbal supplements. Some herbs might interact with the drug, affecting its effectiveness or causing adverse effects. Your doctor can provide personalized guidance based on your health profile and medications.
Combining Different Drugs With Mobicam Tablet DT (Piroxicam) Can Lead To Adverse Effects
Anticoagulants: Piroxicam may enhance the effects of anticoagulant medications, increasing the risk of bleeding.
Lithium: NSAIDs can elevate lithium levels in the blood, necessitating close monitoring and potential dose adjustments.
Diuretics: Combining Piroxicam with diuretics can lead to reduced effectiveness of both drugs and potential kidney issues.
ACE Inhibitors: Concurrent use of ACE inhibitors and Piroxicam can reduce the antihypertensive effects of ACE inhibitors.\
Cyclosporine: Piroxicam can increase the risk of nephrotoxicity when used alongside cyclosporine.
| Manufacturer | : | Cipla Pharma, India |
| Equivalent Brand | : | Feldene |
| Generic Search | : | Piroxicam |
