Introduction

Primigyn Gel contains Dinoprostone, a synthetic form of prostaglandin E2 (PGE2) used primarily for cervical ripening and labor induction in pregnant women. Administered intravaginally under medical supervision, it helps soften and dilate the cervix in preparation for childbirth.

This product is intended for use by pregnant women at or near term who require medical assistance to begin labor due to medical or obstetric indications.

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Precautions of primigyn gel (Dinoprostone)

Strictly for hospital use under continuous fetal and maternal monitoring
Use with caution in women with a history of cesarean delivery, uterine surgery, or multiple pregnancies
Not intended for home use
Discontinue immediately if uterine hyperstimulation or fetal distress occurs

Uses of primigyn gel (Dinoprostone)

Primigyn Gel is prescribed for:

Cervical ripening before labor induction
Induction of labor in women with an unfavorable cervix
Preparation for delivery in cases where early delivery is needed for maternal or fetal reasons
Stimulation of uterine contractions

Side Effects of primigyn gel (Dinoprostone)

While generally safe under hospital settings, Dinoprostone can cause certain side effects.

Common Side Effects (mild to moderate):

Nausea
Vomiting
Diarrhea
Abdominal cramps
Uterine contractions or pain

FAQs of primigyn gel (Dinoprostone)

Q1. How is Primigyn Gel administered?
It is applied intravaginally by a trained healthcare provider in a hospital setting.

Q2. How long does it take to work?
Cervical ripening usually begins within 6–12 hours, but response time varies based on individual physiology.

Q3. Can I go home after administration?
No. You will be monitored in the hospital for labor progression and fetal well-being.

Q4. What happens if the gel doesn’t work?
If labor does not progress, your doctor may consider repeat dosing, mechanical methods, or intravenous oxytocin.

Q5. Is Primigyn Gel safe for the baby?
Yes, when used under medical supervision. However, fetal monitoring is essential to identify any signs of distress early.

Interactions of primigyn gel (Dinoprostone)

Since Primigyn Gel is used in a controlled clinical setting, interactions are rare but may include:

Oxytocin (Pitocin): Should not be used simultaneously or immediately after Dinoprostone due to risk of uterine overstimulation
Other uterotonic agents – increase the risk of complications
Use caution when combined with drugs affecting uterine contractility or cardiovascular function