Dicaris Adults Tablet (Levamisole)

Buy Levamisole Tablet, commonly known by its brand name Dicaris, is an anthelmintic medication primarily used to treat parasitic worm infections in adults.

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Dicaris Adults Tablet (Levamisole 150mg)

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Understanding Dicaris Adults Tablet (Levamisole 150mg) 

Levamisole, commonly known by its brand name Dicaris, is an anthelmintic medication primarily used to treat parasitic worm infections in adults. It belongs to the imidazothiazole class of drugs and exerts its therapeutic effects by disrupting the nervous system of parasitic worms, leading to paralysis and subsequent elimination from the body. Levamisole has been an essential component of many anthelmintic regimens due to its efficacy and safety profile. This article aims to provide an overview of Levamisole's mechanism of action, recommended dosage, and its role in managing parasitic worm infections in adult patients.

Dosage Information:

The dosage of Levamisole (Dicaris) for adult patients varies depending on the type and severity of the worm infection. Typically, a single dose of 150 mg is recommended for common infections like hookworms and roundworms. In more severe cases or infections caused by certain types of worms, a second dose may be administered after two weeks to ensure complete eradication. The tablets are usually taken orally, with or without food, and should be swallowed whole to maximize their efficacy. It is important to strictly follow the prescribed dosage and duration of treatment to achieve optimal results and prevent the development of drug resistance. For patients with underlying health conditions or taking other medications, it is advisable to consult a healthcare professional before initiating Levamisole therapy.

Mechanism of Action:

Levamisole (Dicaris) exhibits its anthelmintic properties through a unique mechanism of action. It acts as a cholinergic agonist, specifically targeting the nicotinic acetylcholine receptors present in the neuromuscular system of parasitic worms. By binding to these receptors, Levamisole causes excessive stimulation of the worms' cholinergic nervous system, leading to paralysis. The paralyzed worms are then expelled from the gastrointestinal tract through natural bowel movements, effectively clearing the infection. Additionally, Levamisole has immunomodulatory properties, which can enhance the host's immune response against the worms and further aid in their elimination. This dual mode of action makes Levamisole highly effective against a wide range of parasitic worm infections in adults.

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Essential Safety Advice to Follow When Using Dicaris Adults Tablet (Levamisole)

  • Allergic Reactions: Patients with a known hypersensitivity to Levamisole or any of its components should avoid using Dicaris. Allergic reactions may manifest as skin rashes, itching, swelling, or difficulty breathing. If any signs of an allergic reaction occur, immediate medical attention should be sought.
  • Pregnancy and Breastfeeding: Levamisole's safety during pregnancy and lactation has not been established, and its use is generally not recommended during these periods. Pregnant or breastfeeding individuals should consult their healthcare provider before initiating treatment with Dicaris.
  • Liver and Kidney Impairment: Patients with liver or kidney impairment may require dose adjustments or close monitoring during Levamisole therapy. The drug's metabolism and excretion may be affected in these conditions, potentially leading to altered drug levels in the body.
  • Blood Disorders: Levamisole can occasionally cause blood-related disorders, such as agranulocytosis and leukopenia. Patients with a history of blood disorders should exercise caution and undergo regular blood tests during treatment.
  • Immune Disorders: Individuals with autoimmune disorders, such as systemic lupus erythematosus or rheumatoid arthritis, should use Levamisole with caution. The drug's immunomodulatory properties might exacerbate these conditions.
  • Neurological Disorders: Levamisole may cause neurotoxicity, resulting in symptoms like dizziness, headache, or confusion. Patients with pre-existing neurological conditions should be closely monitored during therapy.
  • Hepatic Enzyme Inducers/Inhibitors: Concomitant use of drugs that induce or inhibit hepatic enzymes can influence the metabolism of Levamisole, affecting its efficacy and safety. It is essential to inform the healthcare provider about all medications being taken to avoid potential interactions.

Some of the specific indications for Dicaris Adults Tablet (Levamisole) include

Intestinal Worm Infections: Levamisole is primarily used to treat various intestinal worm infections, including ascariasis, hookworm infections, and strongyloidiasis. It is highly effective in paralyzing and eliminating worms, leading to the resolution of symptoms and improvement in the patient's condition.

Immunomodulation in Cancer Treatment: In some cases, Levamisole has been used as an adjunct therapy in certain cancers to enhance the immune response against tumor cells. However, its role in cancer treatment is still under investigation, and its use should be done under the supervision of an oncologist.

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Crucial Side Effects to Be Observed When Using Dicaris Adults Tablet (Levamisole)

  • Gastrointestinal Disturbances: Common side effects of Levamisole may include nausea, vomiting, abdominal pain, and diarrhea. These symptoms are usually mild and self-limiting.
  • Skin Reactions: Levamisole can cause skin reactions, such as rash, itching, and hives. Severe skin reactions are rare but require immediate medical attention.
  • Neurological Symptoms: Some individuals may experience dizziness, headache, or confusion while taking Levamisole. If these symptoms persist or worsen, medical evaluation is recommended.
  • Blood Disorders: Levamisole may rarely lead to blood-related disorders, such as agranulocytosis or leukopenia, which can increase the risk of infections. Regular blood tests are necessary to monitor for such complications.
  • Flu-like Symptoms: Patients may experience flu-like symptoms, including fever, chills, and body aches, during Levamisole therapy. These symptoms are usually transient and resolve on their own.
  • Liver and Kidney Abnormalities: Levamisole may cause transient elevations in liver enzymes or kidney function tests. Close monitoring is essential in patients with pre-existing liver or kidney conditions.
  • Allergic Reactions: Severe allergic reactions to Levamisole, though rare, can manifest as facial swelling, difficulty breathing, or anaphylaxis. Immediate medical attention is necessary if any signs of an allergic reaction occur.

FAQs about Levamisole (Dicaris) Adult Tablet

Can Levamisole be used for children?

Answer: Levamisole (Dicaris) is primarily indicated for use in adults to treat parasitic worm infections. Its safety and efficacy in children may vary, and the dosage should be determined by a pediatrician. It is essential to consult a healthcare professional before administering Levamisole to children.

Is it safe to drive or operate heavy machinery while taking Levamisole?

Answer: Levamisole may cause dizziness and confusion as potential side effects. If you experience such symptoms, avoid driving or operating heavy machinery until you are sure about your ability to perform these tasks safely.

Can Levamisole be taken with food?

Answer: Levamisole (Dicaris) tablets can be taken with or without food. However, if you experience any gastrointestinal discomfort, taking the medication with food may help reduce such side effects.

Can I stop Levamisole if my symptoms improve before completing the full course?

Answer: It is crucial to complete the full course of Levamisole as prescribed, even if your symptoms improve. Stopping the medication prematurely may lead to incomplete elimination of the worms and increase the risk of recurrence or development of drug resistance.

Are there any specific dietary restrictions while on Levamisole therapy?

Answer: There are no specific dietary restrictions associated with Levamisole use. However, maintaining a balanced and nutritious diet can support your overall health and immune function during the treatment course. If you have any concerns about your diet during therapy, consult your healthcare provider or a registered dietitian for personalized advice.

Significant Drug Interactions that Require Attention For Dicaris Adults Tablet (Levamisole)

  • Immunosuppressive Agents: Levamisole's immunomodulatory effects may interfere with the action of immunosuppressive drugs, reducing their efficacy. Careful monitoring and possible dose adjustments may be required when using Levamisole alongside immunosuppressants.
  • Anticoagulants: Levamisole can interact with anticoagulant medications, such as warfarin, potentially altering blood clotting parameters. Close monitoring of blood coagulation levels is necessary when using both drugs together.
  • Cimetidine: Co-administration of Levamisole with cimetidine, a histamine H2 receptor antagonist, can lead to increased Levamisole levels in the body. Dose adjustments may be necessary to prevent adverse effects.
  • Other Anthelmintic Drugs: Concurrent use of Levamisole with other anthelmintic medications may lead to an increased risk of side effects and drug interactions. Avoid using multiple anthelmintic drugs simultaneously unless specifically advised by a healthcare professional.
More Information Demo
Manufacturer : Janssen Pharmaceuticals
Equivalent Brand : Dicaris
Generic Search : Levamisole