Forxiga Tablet (Dapagliflozin)
Dapagliflozin, known by its brand names Forxiga and Farxiga, is a medication used in the management of diabetes. It belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors.
Introduction to Forxiga Tablet (Dapagliflozin)
Dapagliflozin, known by its brand names Forxiga and Farxiga, is a medication used in the management of diabetes. It belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors. These medications are designed to lower blood sugar levels in individuals with type 2 diabetes by preventing the reabsorption of glucose in the kidneys, thus promoting its excretion in the urine. Dapagliflozin is a medication that is highly effective in treating Type 2 Diabetes. It works by reducing the reabsorption of glucose in the kidneys, leading to improved blood sugar control in individuals with this condition.
Dosage Information for Dapagliflozin Tablet
Standard Dosage: The typical starting dose of Dapagliflozin is 5 milligrams (mg) once daily, taken in the morning. This dosage can be adjusted based on individual patient needs and the response to treatment.
Maximum Dosage: In some cases, the dose may be increased to 10 mg once daily if a patient's blood sugar levels remain inadequately controlled on the 5 mg dose.
Missed Dose: If a dose of Dapagliflozin is missed, it should be taken as soon as remembered, unless it's close to the time for the next scheduled dose. In such cases, patients should skip the missed dose and continue with their regular dosing schedule. Doubling up on doses to make up for a missed one is not recommended.
Overdose: In the event of an overdose, medical attention should be sought immediately. Symptoms of an overdose may include severe hypoglycemia (low blood sugar), dehydration, and electrolyte imbalances. Treatment for overdose typically involves supportive care, such as intravenous fluids and monitoring of blood glucose levels.
Special Populations: Dosage adjustments may be necessary for individuals with impaired renal function, as Dapagliflozin is primarily eliminated through the kidneys. It is important to consult a healthcare professional for proper dosing recommendations in such cases.
Dapagliflozin and Metformin:
Dapagliflozin is often prescribed in combination with metformin, another commonly used Diabetes medication. This combination can provide enhanced blood sugar control by targeting different aspects of glucose regulation, offering a comprehensive approach to diabetes management.
Dapagliflozin Price:
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Some of the precautionary measures to be taken while using Forxiga Tablet (Dapagliflozin)
- Kidney Function: It's crucial for healthcare providers to assess kidney function before initiating Dapagliflozin therapy. The drug is primarily excreted through the kidneys, and dose adjustments are necessary in individuals with impaired renal function.
- Dehydration Risk: Patients should be educated about the risk of dehydration while taking Dapagliflozin Medication. Adequate fluid intake should be encouraged, and individuals should be advised to be cautious in hot weather or during illness.
- Hypotension: Dapagliflozin/Farxiga can cause a drop in blood pressure, especially when transitioning from sitting to standing. Patients should rise slowly to minimize the risk of orthostatic hypotension.
- Genital Infections: Individuals should be informed about the increased risk of genital yeast infections and urinary tract infections. Hygiene practices and regular check-ups are important to manage and prevent these infections.
- Surgery and Illness: In situations like surgery or acute illness, it may be necessary to temporarily discontinue Dapagliflozin to prevent complications like dehydration and hypotension. Healthcare providers should be notified in such cases.
Common infections that are often prescribed for Farxiga/Dapagliflozin Tablets
- Diabetes Management: Dapagliflozin tablets are primarily prescribed to individuals with type 2 diabetes to help control blood sugar levels. It works by reducing the reabsorption of glucose in the kidneys, thereby increasing the excretion of glucose in the urine.
- Cardiovascular Benefits: In addition to glycemic control, Dapagliflozin has shown cardiovascular benefits. It has been associated with a reduced risk of cardiovascular events in certain patient populations.
- Heart Failure: Dapagliflozin may also be used to manage heart failure with reduced ejection fraction in adults, particularly when combined with other heart failure medications.
- Renal Protection: Some studies suggest that Dapagliflozin may have renal protective effects, slowing the progression of kidney disease in individuals with type 2 diabetes.
- Weight Management: Patients may experience weight loss while taking Dapagliflozin, which can be beneficial for those with type 2 diabetes who are overweight or obese.
Some of the Secondary Effects of Forxiga Tablet (Dapagliflozin)
- Genitourinary Infections: One common side effect of Dapagliflozin is an increased risk of urinary tract infections and genital yeast infections. Patients should be advised to maintain good hygiene and seek prompt medical attention if they experience symptoms like burning, itching, or discharge.
- Dehydration: Dapagliflozin can lead to an increased risk of dehydration, especially in hot weather or when combined with other medications that can cause fluid loss. Symptoms of dehydration include dry mouth, excessive thirst, weakness, and dizziness.
- Hypoglycemia: While Dapagliflozin is not known to cause hypoglycemia on its own, it can enhance the blood sugar-lowering effects of insulin and other antidiabetic medications, potentially leading to low blood sugar levels.
- Increased Urination: Due to its mechanism of action, Dapagliflozin may cause an increase in urination. This effect is usually mild, but it can be bothersome for some individuals.
- Orthostatic Hypotension: Some patients may experience a drop in blood pressure when standing up, leading to dizziness or fainting. This is more common in individuals with a history of low blood pressure.
Answers to Common Inquiries About Forxiga Tablet (Dapagliflozin)
Q1. Can Dapagliflozin tablets be used alone to manage diabetes?
No, Dapagliflozin is typically used in combination with other diabetes medications to achieve optimal blood sugar control. It works effectively when used as part of a comprehensive diabetes management plan.
Q2. Is it safe to drink alcohol while taking Dapagliflozin?
While moderate alcohol consumption is generally acceptable, excessive alcohol intake can increase the risk of dehydration and hypoglycemia when combined with Dapagliflozin. It's essential to consult your healthcare provider for personalized advice.
Q3. Can Dapagliflozin cause weight gain?
No, Dapagliflozin is often associated with weight loss. It helps reduce excess glucose in the bloodstream by promoting its excretion in the urine, which can lead to a gradual reduction in body weight.
Q4. Are there any dietary restrictions when taking Dapagliflozin?
There are no specific dietary restrictions associated with Dapagliflozin. However, maintaining a balanced diet and monitoring carbohydrate intake is important for effective diabetes management.
Q5. How quickly does Dapagliflozin start to lower blood sugar levels?
Dapagliflozin typically starts to lower blood sugar levels within a few days of starting treatment. However, the exact timeline may vary from person to person, and it may take several weeks to reach the full effect. Regular monitoring with your healthcare provider is essential.
Combining different drugs with Forxiga Tablet (Dapagliflozin) can lead to Adverse Effects
- Diuretics: Combining Dapagliflozin with diuretic medications can increase the risk of dehydration and low blood pressure. Healthcare providers should monitor patients closely when these drugs are used together.
- Insulin and Sulfonylureas: Dapagliflozin can enhance the blood sugar-lowering effects of insulin and sulfonylureas, potentially leading to hypoglycemia. Dose adjustments of these medications may be necessary.
- Rifampin: Rifampin, an antibiotic, can reduce the effectiveness of Dapagliflozin. Patients taking both drugs should be monitored for changes in blood sugar control.
- Phenobarbital and Phenytoin: These anticonvulsant medications can also decrease the effectiveness of Dapagliflozin. Dose adjustments may be needed.
- Digoxin: Dapagliflozin can increase the levels of digoxin in the blood, potentially leading to digoxin toxicity. Monitoring of digoxin levels is advisable when used concurrently.
Manufacturer | : | AstraZeneca |
Equivalent Brand | : | Farxiga |
Generic Search | : | Dapagliflozin |