Generic Nicorandil (Angedil Tablet)
Nicorandil Tablet (Angedil) is a medication used to treat angina pectoris, a condition characterized by chest pain or discomfort caused by insufficient blood flow to the heart muscle.
Generic Nicorandil (Angedil Tablet): Effective for Angina
Nicorandil, marketed under the brand name Angedil, is a medication that is commonly prescribed to treat Angina, a condition characterized by chest pain or discomfort caused by reduced blood flow to the heart. Angedil tablets contain the active ingredient nicorandil, which works by relaxing and widening the blood vessels, thereby improving blood flow to the heart and reducing the workload on the heart.
In the United States, Nicorandil tablets may be available under the same brand name. However, there are alternative medications that can be used as substitutes for nicorandil. It is essential to consult a healthcare professional, such as a doctor or pharmacist, to determine the appropriate substitute medication for your specific condition and to discuss the availability and pricing options in the USA.
Some common substitutes for Nicorandil tablets available in the USA include:
- Isosorbide Mononitrate: It is a medication that belongs to the nitrate class and works by relaxing and widening blood vessels to improve blood flow.
- Isosorbide Dinitrate: It belongs to the class of drugs known as nitrates and works by dilating the blood vessels to improve blood flow and relieve angina symptoms.
- Nifedipine: It is a calcium channel blocker that relaxes and widens blood vessels, improving blood flow to the heart and reducing angina symptoms.
- Amlodipine: Another calcium channel blocker that helps relax blood vessels and improve blood flow, thereby alleviating angina symptoms.
- Isosorbide Dinitrate: This medication is also a nitrate that relaxes and widens blood vessels, promoting better blood flow to the heart.
- Ranolazine: It is an anti-anginal medication that works by improving blood flow to the heart and reducing the workload of the heart muscle.
The dosage of Nicorandil can vary depending on the individual's condition and the recommendation of the prescribing healthcare professional. It is typically available in tablet form, with different strengths ranging from 5 mg to 20 mg. The dosage and frequency of administration will be determined by your doctor.
Nicorandil provides several benefits in the treatment of angina. Some of the key benefits include:
Vasodilation: Nicorandil helps to relax and widen the blood vessels, improving blood flow to the heart muscle. This increased blood flow helps to alleviate chest pain and reduce the frequency and severity of angina attacks.
Anti-ischemic effects: By improving blood flow to the heart, Nicorandil helps to reduce the risk of ischemia, which is a condition where the heart muscle doesn't receive enough oxygen-rich blood. This can help prevent Heart and Blood Pressure function.
Antiplatelet effects: Nicorandil has been found to have mild antiplatelet effects, meaning it can help prevent the formation of blood clots. This can be beneficial in reducing the risk of cardiovascular events such as heart attacks or strokes.
Looking to buy Nicorandil Tablet online? Find the best deals on Nicorandil tablet prices on 1mgstore.com. Purchase with confidence and get fast and reliable delivery.
How Nicorandil works:
Nicorandil works through two main mechanisms:
Activation of ATP-sensitive potassium channels: Nicorandil activates ATP-sensitive potassium channels present in the smooth muscle cells lining the blood vessels. This activation leads to the relaxation of the blood vessels, resulting in vasodilation and improved blood flow to the heart.
Nitric oxide release: Nicorandil also stimulates the release of nitric oxide, a natural substance that helps dilate blood vessels. Nitric oxide promotes vasodilation, further enhancing blood flow to the heart.
By combining these mechanisms, Nicorandil effectively improves blood supply to the heart, reduces cardiac workload, and relieves the symptoms of angina. It is important to note that the information provided here is a general overview. The specific dosage, benefits, and mechanism of action may vary depending on individual circumstances and should be discussed with a healthcare professional who can provide personalized advice and guidance.
Before taking Nicorandil (Angedil), there are some important precautions to keep in mind:
-
Inform your doctor if you have any allergies or medical conditions, especially liver or kidney disease, low blood pressure, or heart disease.
-
Let your doctor know about all medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements. Nicorandil may interact with certain medications, such as nitroglycerin and blood pressure-lowering drugs.
-
Nicorandil may cause dizziness or lightheadedness, especially when standing up from a lying or sitting position. Avoid driving or operating machinery until you know how the medication affects you.
-
Do not drink alcohol while taking Nicorandil, as it may worsen certain side effects.
-
Nicorandil may cause headaches, flushing, or other side effects. If you experience any concerning symptoms, speak with your doctor.
-
Nicorandil should not be taken during pregnancy or while breastfeeding, as its effects on the fetus or infant are not known.
-
If you miss a dose of Nicorandil, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Overall, it is essential to follow your doctor's instructions carefully when taking Nicorandil (Angedil) to ensure its safe and effective use.
Primary Use to be noted down with Nicorandil Tablet (Angedil)
Nicorandil (Angedil) is primarily used to treat angina pectoris, a condition characterized by chest pain or discomfort caused by insufficient blood flow to the heart muscle.
Nicorandil is also used in some cases to treat other conditions, such as:
-
Chronic stable angina: Nicorandil may be used to treat chronic stable angina, a type of angina that occurs during physical activity or emotional stress and is relieved by rest or medication.
-
Heart failure: Nicorandil may be used to treat heart failure, a condition in which the heart is unable to pump enough blood to meet the body's needs.
-
Pulmonary hypertension: Nicorandil may be used to treat pulmonary hypertension, a condition in which there is high blood pressure in the arteries that supply blood to the lungs.
In some cases, Nicorandil may be used off-label for other conditions, such as peripheral arterial disease or Raynaud's phenomenon. It is important to note that Nicorandil should only be used under the guidance and supervision of a qualified healthcare professional.
Nicorandil Tablet (Angedil) has some secondary effects, such as:
Nicorandil (Angedil) is a medication that is primarily used to treat angina, a condition characterized by chest pain or discomfort due to reduced blood flow to the heart. Like any medication, Nicorandil may cause some side effects in some people. Some common side effects associated with Nicorandil include:
- Headache
- Dizziness
- Flushing
- Nausea
- Vomiting
- Diarrhea
- Weakness
- Fainting
- Skin rash
- Abnormal heartbeat
Some of these side effects may subside over time as your body adjusts to the medication. However, if you experience any of these side effects or any other unusual symptoms, it is important to contact your healthcare provider right away. Additionally, if you experience severe or persistent side effects, you should seek emergency medical attention.
Can Nicorandil cause breathing difficulties?
Answer: Breathing difficulties are not commonly associated with Nicorandil. However, if you experience any respiratory problems while taking the medication, it is advisable to consult your healthcare provider for evaluation.
Can Nicorandil cause changes in blood glucose levels?
Answer: Nicorandil does not typically have a significant impact on blood glucose levels. However, if you have diabetes and are taking medications to control your blood sugar, it is important to monitor your blood glucose levels regularly while using Nicorandil.
Can Nicorandil be used during pregnancy?
Answer: The use of Nicorandil during pregnancy is generally not recommended. It is important to discuss the potential risks and benefits with your healthcare provider, as they can provide guidance specific to your situation.
Can Nicorandil be used in elderly patients?
Answer: Nicorandil can be used in elderly patients, but caution should be exercised, especially if they have other underlying medical conditions or are taking multiple medications. Close monitoring by a healthcare provider is important to ensure the medication is well-tolerated and effective in this population.
Is Nicorandil safe for everyone to take?
Answer: Nicorandil is not safe for everyone to take, and it should not be used by people with severe liver or kidney disease, low blood pressure, or certain heart conditions. It may also interact with other medications, so it is essential to inform your doctor of all medications you are currently taking
Here are some notable interactions to keep in mind with Nicorandil Tablet (Angedil)
-
Nitroglycerin: Taking Nicorandil with nitroglycerin may cause a severe drop in blood pressure, leading to dizziness, fainting, or even a heart attack.
-
Blood pressure-lowering drugs: Nicorandil may enhance the effects of other blood pressure-lowering drugs, such as beta-blockers or calcium channel blockers, leading to excessively low blood pressure.
-
Sildenafil: Taking Nicorandil with sildenafil (Viagra) may increase the risk of low blood pressure, dizziness, or fainting.
-
Potassium-sparing diuretics: Nicorandil may increase the risk of high potassium levels in the blood when taken with potassium-sparing diuretics, such as spironolactone.
-
Alcohol: Drinking alcohol while taking Nicorandil may increase the risk of side effects, such as dizziness or flushing.
-
CYP3A4 inhibitors: Nicorandil is metabolized by the CYP3A4 enzyme in the liver, and drugs that inhibit this enzyme, such as ketoconazole or erythromycin, may increase the levels of Nicorandil in the body, leading to an increased risk of side effects.
-
CYP3A4 inducers: Drugs that induce the CYP3A4 enzyme, such as rifampicin or phenytoin, may decrease the levels of Nicorandil in the body, reducing its efficacy.
Overall, it is essential to discuss any potential interactions with your doctor before taking Nicorandil (Angedil) and to inform them of all medications you are taking.
| Manufacturer | : | Healing Pharma |
| Equivalent Brand | : | Nicorandil |
| Generic Search | : | Nicorandil |
