Isentress Tablet (Raltegravir)

Buy Raltegravir, commonly known by its brand name Isentress, is a breakthrough antiretroviral drug used in the treatment of HIV infection.

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Isentress 400mg Tablet (Raltegravir 400mg)

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60 Tablet/s $289.63
120 Tablet/s $579.30
180 Tablet/s $869.00

Raltegravir Tablet: An Effective Antiretroviral Agent

What is Raltegravir?

Raltegravir, commonly known by its brand name Isentress, is a breakthrough antiretroviral drug used in the treatment of HIV infection. It belongs to the class of medications known as integrase strand transfer inhibitors (INSTIs). Raltegravir is widely regarded as a milestone in HIV therapy, bringing renewed hope to millions of people living with the virus. In this article, we will explore the dosage information, uses, and benefits of Raltegravir tablets, the generic version of the drug, and how it has revolutionized HIV treatment.

Raltegravir Tablet: Dosage Information

Raltegravir tablets come in various strengths, typically ranging from 400mg to 600mg, and are available for oral administration. The recommended dosage may vary depending on the patient's age, medical condition, and other factors. It is crucial to follow the prescribed dosage and consult a healthcare professional before starting or modifying the treatment. For adults and pediatric patients weighing at least 40kg, the usual dosage of Raltegravir is 400mg twice daily. Pediatric patients weighing between 20kg and 40kg may be prescribed 250mg twice daily. The tablets can be taken with or without food. For patients with impaired renal function or those undergoing hemodialysis, dosage adjustments may be necessary.

Raltegravir Cost in USA:
At, we understand the importance of affordable healthcare, and that's why we offer competitive prices for Raltegravir in the USA. Our goal is to ensure that life-saving medications, like Raltegravir, remain accessible to everyone who needs them. With our commitment to quality and cost-effectiveness, you can trust us to provide the best value for your healthcare needs, delivering Raltegravir right to your doorstep.

Raltegravir Cost:
At, we strive to offer the most competitive prices for Raltegravir, both in the USA and internationally. We believe that access to essential medications should not be a financial burden. By providing affordable options for Raltegravir, we aim to contribute to improved health outcomes and better quality of life for those living with HIV. Count on us for reliable service, genuine products, and cost-effective solutions for your healthcare needs.

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Important Drug Interconnections with Isentress Tablet (Raltegravir) must be noticed

While Raltegravir (Isentress) is considered a life-saving drug in the treatment of HIV, there are several important precautions that patients should be aware of to ensure safe and effective use:

  • Medical History: Before starting Raltegravir therapy, patients must disclose their complete medical history to their healthcare provider. Special attention should be given to any history of kidney or liver problems, as well as any allergic reactions to medications.
  • Pregnancy and Breastfeeding: Pregnant women should inform their doctor about their pregnancy status before starting Raltegravir treatment. Although Raltegravir is generally considered safe during pregnancy, its use should be discussed with a healthcare provider to assess potential risks and benefits. Similarly, breastfeeding women should consult their healthcare provider, as the drug's presence in breast milk is not well-established.
  • Pediatric Use: Raltegravir is approved for use in children, but appropriate dosage adjustments may be necessary based on age and weight. Parents or guardians should closely follow the healthcare provider's instructions for administering the drug to children.
  • Renal Impairment: Patients with impaired kidney function may require dosage adjustments or alternative treatment options. Regular monitoring of kidney function is essential during Raltegravir therapy.
  • Hepatic Impairment: Individuals with liver impairment should be closely monitored during Raltegravir treatment, as the drug is metabolized in the liver. Dose adjustments may be necessary for patients with moderate to severe liver dysfunction.
  • Drug Allergies: Patients with a history of allergic reactions to Raltegravir or any of its components should not use the drug. Allergic reactions may include rash, itching, swelling, severe dizziness, or difficulty breathing. If any such symptoms occur, immediate medical attention is required.
  • Concomitant Medications: Inform your healthcare provider about all medications, supplements, or herbal products you are currently taking. Some drugs may interact with Raltegravir, potentially affecting its effectiveness or increasing the risk of side effects.

Some of the specific indications for Isentress Tablet (Raltegravir) include

  • HIV Treatment: The primary use of Raltegravir is in the treatment of HIV-1 infection. As an integrase strand transfer inhibitor, the drug prevents the integration of viral DNA into the host cell's genome, thereby inhibiting viral replication. This helps control the virus and reduces the viral load, leading to improved immune function and slower disease progression.
  • First-line Therapy: Raltegravir is a Life-Saving Drug, often included in first-line antiretroviral therapy regimens due to its high efficacy and tolerability. When combined with other antiretroviral drugs, it can significantly suppress viral replication and increase the patient's CD4 cell count.
  • Treatment-Experienced Patients: Raltegravir is also prescribed to patients who have developed resistance to other antiretroviral agents. Its unique mechanism of action makes it effective against certain drug-resistant strains of HIV, providing viable treatment options for these patients.
  • Prevention of Mother-to-Child Transmission: Raltegravir may be used in pregnant women with HIV to prevent the transmission of the virus to their newborns. Its safety profile during pregnancy makes it a suitable option for this critical indication.
  • Post-Exposure Prophylaxis (PEP): In some cases of potential HIV exposure, such as accidental needle sticks or unprotected sexual intercourse, Raltegravir may be prescribed as part of a post-exposure prophylaxis regimen to reduce the risk of HIV transmission.

Important Adverse effects of using Isentress Tablet (Raltegravir) must be noticed

Like all medications, Raltegravir may cause side effects, although not everyone experiences them. Some common side effects of Raltegravir include:

  • Nausea and Vomiting: Some patients may experience mild gastrointestinal disturbances, such as nausea or vomiting, especially during the initial days of treatment. Taking the medication with food can help alleviate these symptoms.
  • Headache: Headaches are relatively common but usually mild and transient.
  • Fatigue: Some patients may experience fatigue or weakness, which should be reported to a healthcare provider if severe or persistent.
  • Skin Rash: Raltegravir can rarely cause skin reactions, ranging from mild rash to severe allergic reactions. Any skin changes should be promptly reported to a healthcare professional.
  • Insomnia: Difficulty falling or staying asleep may occur in some individuals.
  • Abnormal Liver Function Tests: Raltegravir can affect liver function in some patients, leading to elevated liver enzyme levels. Regular liver function monitoring is essential during treatment.
  • Depression: In rare cases, Raltegravir has been associated with mood changes or symptoms of depression. Patients should be vigilant and seek medical advice if they experience mood alterations.
  • Serious Allergic Reactions: Although rare, severe allergic reactions may occur. Signs of a serious allergic reaction include rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing. Seek immediate medical attention if any of these symptoms manifest.

FAQs about Raltegravir (Isentress) Tablet

Can I take Raltegravir with food?

Yes, Raltegravir can be taken with or without food. However, if you experience stomach upset, taking it with a meal can help reduce gastrointestinal discomfort.

Can Raltegravir be used to prevent HIV transmission during intercourse?

No, Raltegravir is not approved for use as a stand-alone preventive measure (PrEP). For HIV prevention, consult a healthcare provider to discuss appropriate pre-exposure prophylaxis options.

Is Raltegravir safe for elderly patients?

Yes, Raltegravir can be used in elderly patients. However, dose adjustments may be required based on individual health status and other medications they are taking.

Can Raltegravir cure HIV completely?

No, Raltegravir is not a cure for HIV. It is part of antiretroviral therapy that helps control the virus, manage symptoms, and improve the patient's quality of life.

What should I do if I miss a dose of Raltegravir?

If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for the missed one. Consult your healthcare provider if you have any concerns.

Some notable drug interactions with Isentress Tablet (Raltegravir) include:

Raltegravir may interact with other medications, leading to altered drug levels in the body or reduced efficacy.

  • Antacids: Taking Raltegravir simultaneously with antacids containing aluminum or magnesium hydroxide can reduce the absorption of Raltegravir, leading to decreased effectiveness. It is advisable to separate the administration of these medications by at least two hours.
  • Proton Pump Inhibitors (PPIs): PPIs like omeprazole and esomeprazole may reduce the absorption of Raltegravir. If co-administration is necessary, Raltegravir should be taken two hours before or six hours after PPIs.
  • Rifampin: Co-administration of Raltegravir with rifampin, an antibiotic used to treat tuberculosis, can significantly decrease Raltegravir levels. Alternative antiretroviral therapies should be considered in patients requiring rifampin.
  • Efavirenz and Etravirine: These medications may reduce Raltegravir levels in the blood, potentially compromising its effectiveness. Dose adjustments may be necessary when used together.
  • St. John's Wort: Herbal products containing St. John's Wort can lower Raltegravir concentrations, increasing the risk of treatment failure. Avoid concomitant use with Raltegravir.
More Information Demo
Manufacturer : MSD Ltd, India
Equivalent Brand : Isentress
Generic Search : Raltegravir