Nizonide Tablet (Nitazoxanide)

Buy Nitazoxanide 500mg Tablet is an antiprotozoal and antihelminthic medication that has been used to treat a variety of parasitic infections. It is sold under different brand names, including Alinia and Nizonide.

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Nizonide Tablet (Nitazoxanide 500mg)

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30 Tablet/s $20.00
60 Tablet/s $40.00
90 Tablet/s $60.00

Nizonide Tablet DT (Nitazoxanide 200mg)

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30 Tablet/s $15.00
60 Tablet/s $30.00
90 Tablet/s $45.00

Information About Nitazoxanide 500mg Tablet 

Nitazoxanide is an antiprotozoal and antihelminthic medication that has been used to treat a variety of parasitic infections. It is sold under different brand names, including Alinia and Nizonide. The drug is effective against a range of parasites, making it a versatile option for managing certain gastrointestinal infections caused by protozoa and helminths. Nitazoxanide Tablet Brand contains the active ingredient Nitazoxanide and is manufactured by different pharmaceutical companies. Each brand may have slight variations in formulation, dosages, and packaging, but they share the same therapeutic efficacy against parasitic infections. It is essential for patients to be aware of the specific brand they are prescribed and to use the medication as directed by their healthcare provider. The Nizonide brand is manufactured by Lupin Ltd.

Dosage Information:

The dosage of Nitazoxanide tablets may vary depending on the specific infection being treated and the patient's age and weight. It is crucial to follow the doctor's prescribed dosage instructions and never exceed the recommended amount. Generally, Nitazoxanide is available in tablet form, with each tablet containing a specific concentration of the active ingredient.

For adults and children over 12 years old:

The usual recommended dosage for treating diarrhea caused by protozoa is 500 mg twice daily for three days.
For treating intestinal parasitic infections, the recommended dosage is usually 1000 mg (2 tablets of 500 mg each) twice daily for three days.

For children aged 4 to 11 years:

The typical dosage for diarrhea caused by protozoa is 200 mg or 100 mg (depending on the formulation) twice daily for three days.
For treating intestinal parasitic infections, the usual dosage is 500 mg (1 tablet) twice daily for three days.
It is essential to administer the tablets with food to enhance absorption and minimize gastrointestinal discomfort. If there are any difficulties swallowing the tablets, they can be crushed and mixed with a small amount of food or beverage for easier administration. 

Nitazoxanide Tablet Alternatives:

There are several alternatives to Nitazoxanide tablets for the treatment of parasitic infections. Some common alternatives include metronidazole, tinidazole, albendazole, and mebendazole. These medications also have antiparasitic properties and may be prescribed by healthcare professionals based on the specific infection being treated, the patient's medical history, and other factors. It is essential to follow the doctor's recommendations and complete the full course of treatment to achieve effective parasite eradication and symptom relief.

Nitazoxanide Tablet Benefits:

Nitazoxanide tablets offer several benefits in the treatment of parasitic infections. As a broad-spectrum antiparasitic agent, Nitazoxanide effectively targets a range of protozoa and helminths, making it a versatile choice for gastrointestinal infections like cryptosporidiosis, giardiasis, and amebiasis. The medication is generally well-tolerated and can be used in both adults and children, making it suitable for various patient populations. Additionally, its short treatment duration of just a few days enhances compliance and reduces the risk of developing drug resistance. Nitazoxanide's efficacy and safety profile make it a valuable option in the management of parasitic infections worldwide.

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Before starting Nitazoxanide treatment, patients and healthcare providers should consider the following precautions:

  • Pregnancy and Breastfeeding: The safety of Nitazoxanide during pregnancy and breastfeeding has not been established conclusively. It should only be used if the potential benefits outweigh the risks and under the supervision of a healthcare professional.
  • Liver and Kidney Impairment: Patients with liver or kidney impairments should be closely monitored while on Nitazoxanide therapy, as the drug is primarily metabolized in the liver and excreted through the kidneys.
  • Allergies and Sensitivities: Individuals with known allergies or sensitivities to Nitazoxanide or any of its components should avoid using the medication and seek alternative treatments.
  • Immunocompromised Patients: Immunocompromised patients, such as those with HIV/AIDS or undergoing immunosuppressive therapy, may be at higher risk of infections. Nitazoxanide may be used in such cases but should be closely monitored by a healthcare professional.
  • Driving and Operating Machinery: Nitazoxanide may cause dizziness or drowsiness in some individuals. Patients should avoid driving or operating heavy machinery if they experience these side effects.

Some of the specific indications for Nitazoxanide Tablets include

Nitazoxanide, available as Alinia and Nizonide, is primarily used to treat specific parasitic infections affecting the gastrointestinal system. The drug's broad-spectrum activity makes it effective against the following conditions:

  • Cryptosporidiosis: Nitazoxanide is an essential treatment for cryptosporidiosis, a diarrheal disease caused by the parasite Cryptosporidium. This infection is especially common in immunocompromised individuals and can lead to severe dehydration.
  • Giardiasis: Giardiasis is another gastrointestinal infection caused by the parasite Giardia lamblia. Nitazoxanide is effective in eradicating the parasite and alleviating the symptoms of diarrhea and abdominal discomfort.
  • Amebiasis: Amebiasis is caused by the protozoan parasite Entamoeba histolytica. Nitazoxanide is an option for treating this infection, particularly in asymptomatic carriers or mild cases.
  • Intestinal Parasitic Infections: Nitazoxanide can be used to treat various intestinal infections caused by other parasitic worms, such as roundworms and tapeworms.

It's crucial to note that Nitazoxanide should only be used for the specific indications approved by healthcare professionals, and self-medication should be avoided

While Nitazoxanide is generally well-tolerated, some individuals may experience side effects.

Common side effects may include:

  • Nausea and Vomiting: Some patients may experience mild to moderate nausea or vomiting during treatment.
  • Abdominal Discomfort: Nitazoxanide can cause mild abdominal pain or discomfort in some cases.
  • Headache: Headaches are another potential side effect reported by some patients.
  • Dizziness: Rarely, Nitazoxanide may cause dizziness or lightheadedness.
  • Allergic Reactions: In rare cases, individuals may experience allergic reactions such as rash, itching, swelling, or difficulty breathing. If any of these symptoms occur, immediate medical attention should be sought.

It is important to inform the prescribing healthcare professional if any side effects are experienced, especially if they are severe or persistent.

Frequently Asked Queries About Nitazoxanide Tablet

FAQ: Is Nitazoxanide safe for use in children?

Answer: Yes, Nitazoxanide is safe for use in children aged 4 years and above, with appropriate dosage adjustments based on their age and weight. It is an effective treatment for parasitic infections like giardiasis and cryptosporidiosis in pediatric patients. However, always consult a healthcare professional before administering Nitazoxanide to children and adhere to the prescribed dosage to ensure safety and efficacy.

FAQ: Can Nitazoxanide be taken with food?

Answer: Yes, Nitazoxanide tablets should be taken with food to enhance its absorption and reduce the likelihood of gastrointestinal discomfort. Taking the medication with a meal helps ensure that it is properly absorbed and metabolized by the body, optimizing its therapeutic effect against parasitic infections.

FAQ: Can Nitazoxanide be used to treat viral infections?

Answer: No, Nitazoxanide is specifically indicated for the treatment of parasitic infections like giardiasis, cryptosporidiosis, and amebiasis. It has no antiviral activity and is not effective against viral infections such as the common cold, flu, or COVID-19. It is crucial to use Nitazoxanide only for approved indications under the guidance of a healthcare professional.

FAQ: How long does it take for Nitazoxanide to start working?

Answer: The onset of action for Nitazoxanide varies depending on the specific infection being treated. In most cases, patients may experience relief from symptoms like diarrhea and abdominal discomfort within a few days of starting treatment. However, it is essential to complete the full course of Nitazoxanide as prescribed by the healthcare professional to ensure complete eradication of the parasite and prevent recurrence.

FAQ: Can Nitazoxanide be used during pregnancy?

Answer: The safety of Nitazoxanide during pregnancy has not been conclusively established. It should only be used during pregnancy if the potential benefits outweigh the risks and under the supervision of a healthcare professional. Pregnant women should consult their doctor before starting Nitazoxanide therapy and explore alternative treatment options if available. Additionally, women of childbearing age should use effective contraception during treatment with Nitazoxanide to prevent unintended pregnancy.

Some potential drug interactions with Nitazoxanide Tablets include:

Nitazoxanide may interact with certain medications and substances, potentially affecting their efficacy or safety. It is essential to inform the healthcare professional about all medications, supplements, and herbal products being taken before starting Nitazoxanide therapy.

  • Warfarin: Nitazoxanide may increase the effects of warfarin, leading to an increased risk of bleeding. Close monitoring of blood clotting parameters is advised.
  • Antacids: Taking antacids with Nitazoxanide may decrease the drug's absorption, reducing its effectiveness. It is advisable to separate the administration of antacids and Nitazoxanide by a few hours.
  • Cimetidine: Cimetidine, a medication used to treat acid reflux and peptic ulcers, may increase the concentration of Nitazoxanide in the blood. Dose adjustments may be necessary.
  • Rifampin: Rifampin, an antibiotic, may decrease the concentration of Nitazoxanide in the blood, potentially reducing its effectiveness.
  • Medications Metabolized by CYP450 Enzymes: Nitazoxanide may interfere with the metabolism of certain medications that are processed by the CYP450 enzyme system.

Patients should always consult their healthcare provider before combining Nitazoxanide with any other medication or substance.

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Manufacturer : Lupin Pharma, India
Equivalent Brand : Alinia
Generic Search : Nitazoxanide