Unwanted Tablet (Mifepristone) | Used for Medical Termination of Early Pregnancy

Precaution

1. Use Only as Prescribed

Take Unwanted Tablet only according to the instructions of a qualified healthcare professional. Do not change the dose or treatment schedule yourself.

2. Confirm the Pregnancy Location

An ectopic pregnancy must be ruled out before treatment. Mifepristone does not treat ectopic pregnancy, which can become a serious medical emergency if untreated.

3. Confirm the Pregnancy Duration

The appropriate treatment depends on how far the pregnancy has progressed. The FDA-approved mifepristone regimen with Misoprostol is indicated through 70 days of gestation.

4. Follow the Misoprostol Schedule

Mifepristone is used together with Misoprostol in the approved regimen. Follow the prescribed timing and instructions exactly.

5. IUD in Place

Tell your healthcare professional if you have an intrauterine device. An IUD should be removed before starting the specific mifepristone regimen for medical termination.

6. Bleeding Disorders

Inform your doctor if you have a bleeding disorder because significant bleeding can occur during medical termination.

7. Blood-Thinning Medicines

Tell your healthcare professional if you take anticoagulants or other medicines that affect blood clotting. These medicines can increase concerns related to bleeding.

Usage 

• Take Unwanted Tablet exactly as prescribed by your healthcare professional.
• The FDA-approved regimen uses Mifepristone 200 mg orally on Day 1, followed 24–48 hours later by Misoprostol according to the prescribed regimen.
• Do not change the interval between Mifepristone and Misoprostol without medical advice.
• Swallow the Mifepristone tablet as directed.
• Vaginal bleeding and abdominal cramping may occur after the Misoprostol component.

Uses

1. Medical Termination of Early Intrauterine Pregnancy

Unwanted 200mg Tablet is used with Misoprostol for medical termination of an early intrauterine pregnancy within the approved gestational-age range.

2. Progesterone Blockade

Mifepristone blocks progesterone receptors and interferes with the hormonal support required to maintain pregnancy.

3. Preparation for Misoprostol

Mifepristone helps prepare the uterus for the subsequent action of Misoprostol, which produces uterine contractions.

4. Medication-Based Pregnancy Termination

Mifepristone forms part of a nonsurgical medication regimen for early intrauterine pregnancy termination when clinically appropriate.

Side Effects

Common Side Effects

• Vaginal bleeding
• Abdominal cramping
• Nausea
• Vomiting
• Diarrhea
• Headache
• Dizziness

Serious Side Effects

Seek urgent medical attention for:

• Prolonged or very heavy vaginal bleeding
• Severe or persistent abdominal pain
• Fainting or severe weakness
• Sustained fever
• Severe pelvic pain
• Foul-smelling vaginal discharge
• Symptoms suggesting serious infection

FAQs

1. What is Unwanted Tablet used for?

Unwanted 200mg Tablet contains Mifepristone and is used with Misoprostol for medical termination of an early intrauterine pregnancy within the approved gestational-age range.

2. What does Unwanted Tablet contain?

Unwanted 200mg Tablet contains Mifepristone 200 mg.

3. How does Unwanted Tablet work?

Mifepristone blocks progesterone, a hormone needed to maintain pregnancy. This helps stop the pregnancy from continuing and prepares the uterus for the action of Misoprostol.

4. Is Unwanted Tablet used alone?

For the FDA-approved medical-abortion regimen, Mifepristone is used together with Misoprostol. The prescribed regimen should be followed exactly.

5. Does Unwanted Tablet cause bleeding?

Vaginal bleeding can occur during the treatment process, particularly after Misoprostol. Very heavy or prolonged bleeding requires urgent medical evaluation.

6. Can Unwanted Tablet treat ectopic pregnancy?

No. Mifepristone does not treat ectopic pregnancy. Ectopic pregnancy must be ruled out before the medical-abortion regimen is used.

7. Is follow-up required after taking Unwanted Tablet?

Yes. Follow-up is required to confirm that the pregnancy has been completely terminated.

Interactions

1. Corticosteroid Medicines

Mifepristone can interfere with glucocorticoid activity. Tell your doctor if you use corticosteroids, especially long-term therapy.

2. Blood-Thinning Medicines

Tell your doctor if you take anticoagulants or other medicines that affect blood clotting because bleeding is an important consideration during treatment.

3. CYP3A4 Inhibitors

Some medicines that inhibit CYP3A4 can increase mifepristone exposure. Your healthcare professional should review your medicines before treatment.

4. CYP3A4 Inducers

Some medicines that induce CYP3A4 can reduce mifepristone exposure and potentially affect its activity.

5. Rifampicin

Rifampicin is a CYP3A4 inducer and can affect mifepristone metabolism. Inform your healthcare professional if you take it.

6. Certain Anticonvulsants

Some anticonvulsants, including phenytoin, carbamazepine, and phenobarbital, can induce CYP3A4 and may affect mifepristone exposure.

7. St. John's Wort

St. John's Wort can affect CYP3A4 activity and may alter mifepristone levels. Tell your healthcare professional if you use this supplement.