Zyrik Tablet (Allopurinol)

Buy Zyrik (generic name Allopurinol) is a medication used to treat conditions such as gout, kidney stones, and high uric acid levels in the blood. It works by reducing the amount of uric acid produced by the body. Zyloprim is another brand name for Allopurinol.

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Zyrik 100mg Tablet (Allopurinol 100mg)

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30 Tablet/s $6.40
60 Tablet/s $11.80
90 Tablet/s $17.20

Zyrik 300mg Tablet (Allopurinol 300mg)

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30 Tablet/s $7.20
60 Tablet/s $13.20
90 Tablet/s $18.60

Introduction of Zyrik Tablet (Allopurinol)

Allopurinol, marketed under various brand names such as Zyloric, Lopurin, and Zyloprim, is a medication primarily prescribed for the treatment of conditions related to excess uric acid production and deposition in the body. This comprehensive guide provides detailed information about Allopurinol tablets, including dosage instructions, usage, potential side effects, precautions, and drug interactions. 

How Allopurinol Works:

Allopurinol operates by targeting the enzyme xanthine oxidase, a crucial player in the body's production of uric acid. Uric acid is a natural waste product formed during the breakdown of purines, compounds found in certain foods and tissues. Elevated levels of uric acid can lead to the formation of urate crystals, responsible for gout and related conditions. Allopurinol works by inhibiting xanthine oxidase, the enzyme responsible for converting hypoxanthine and xanthine into uric acid. By doing so, it reduces the overall production of uric acid. As uric acid levels decrease, the likelihood of urate crystal formation in joints, kidneys, and other tissues diminishes, thereby lowering the risk of gout attacks and associated complications. It's worth noting that Allopurinol doesn't provide immediate relief for ongoing gout attacks; rather, it's a preventive measure to manage uric acid levels over the long term. Its effectiveness is gauged through consistent use and monitoring of uric acid levels in the blood.

Allopurinol Dosage Information

Dosage Recommendations: The dosage of Allopurinol varies depending on the individual's condition and response to treatment. The typical starting dose for adults is 100 to 300 milligrams daily, taken as a single dose or divided into multiple doses. The dosage can be adjusted based on the serum uric acid levels and the patient's tolerance to the medication.

Missed Dose: If a dose is missed, it should be taken as soon as remembered. However, if it's close to the next scheduled dose, the missed dose should be skipped and the regular dosing schedule should be resumed. Doubling the dose to make up for a missed one is not recommended, as it can lead to adverse effects.

Overdose: In case of an overdose, medical attention should be sought immediately. Symptoms of an overdose may include severe dizziness, nausea, vomiting, diarrhea, and joint pain. Overdosing on Allopurinol can lead to serious complications, and medical supervision is crucial.

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Essential Safety Advice to Follow when Using Zyrik Tablet (Allopurinol)

Before taking Zyrik (Allopurinol), it's important to inform a healthcare professional about any medical conditions or allergies. Additionally, certain precautions should be taken while using Zyrik:

  1. Kidney or liver disease: Zyrik/Zyloprim may not be suitable for individuals with kidney or liver disease. A healthcare professional should be consulted before starting the medication.

  2. Pregnancy and breastfeeding : Zyrik may not be safe for pregnant or breastfeeding individuals. A healthcare professional should be consulted before starting the medication.

  3. Allergies: Individuals who are allergic to allopurinol or any other ingredient in Zyrik should not take the medication.

  4. Drug interactions: Zyrik may interact with other medications, including blood thinners, diuretics, and certain antibiotics. A healthcare professional should be informed of all medications being taken before starting Zyrik.

  5. Dehydration: It's important to drink plenty of fluids while taking Zyrik to prevent kidney stones. Dehydration may increase the risk of kidney stones.

  6. Skin reactions: Zyrik may cause skin reactions, including rash and hives. A healthcare professional should be consulted if any skin reactions occur.

  7. Surgery: It's important to inform a healthcare professional that Zyrik is being taken before any surgery or medical procedure.

Overall, Zyrik is a safe and effective medication for managing conditions related to high levels of uric acid in the body. However, it's important to take precautions and consult a healthcare professional before starting the medication.

Some of the uses of Zyloprim/Allopurinol (Zyrik) include:

  1. Gout treatment: Allopurinol is commonly used to prevent Gout attacks by lowering the levels of uric acid in the blood. It can be used to treat acute gout attacks, but it is not effective in relieving pain during an attack.

  2. Kidney stone prevention: Allopurinol can also be used to prevent the formation of Kidney stones caused by high levels of uric acid. It works by reducing the amount of uric acid in the urine, which helps to prevent the formation of crystals.

  3. Chemotherapy-induced hyperuricemia: Allopurinol can be used to manage the high levels of uric acid that can occur as a side effect of chemotherapy.

  4. Cardiovascular disease: Some studies suggest that allopurinol may have a protective effect against heart disease by reducing inflammation and oxidative stress.

  5. Lesch-Nyhan syndrome: Allopurinol can be used to treat the symptoms of this rare genetic disorder, which causes hyperuricemia and other neurological problems.

It is important to note that allopurinol should be used only under the supervision of a doctor, as it can cause serious side effects if not taken properly. Common side effects include rash, nausea, and diarrhea, while more serious side effects can include liver or kidney damage, bone marrow suppression, and hypersensitivity syndrome.

There are some potential side effects associated with Zyrik Tablet (Allopurinol) use, including:

Allopurinol, sold under the brand name Zyloprim or Zyrik, is a medication used to treat gout and kidney stones caused by high levels of uric acid in the blood. While it is generally well-tolerated.

  1. Skin rash: One of the most common side effects of allopurinol is a skin rash, which can range from mild to severe. It is more common in people who have a history of allergic reactions to other medications.

  2. Nausea and vomiting: Allopurinol can cause gastrointestinal side effects such as nausea, vomiting, and diarrhea. These symptoms are usually mild and go away on their own, but if they persist, you should contact your doctor.

  3. Liver and kidney damage: Allopurinol can cause liver or kidney damage in rare cases. If you experience symptoms such as yellowing of the skin or eyes, abdominal pain, or dark urine, you should seek medical attention immediately.

  4. Bone marrow suppression: Allopurinol can cause a decrease in the production of blood cells in the bone marrow, which can lead to anemia, easy bruising or bleeding, and an increased risk of infection.

  5. Hypersensitivity syndrome: A rare but serious side effect of allopurinol is hypersensitivity syndrome, which can cause fever, rash, and multi-organ failure. If you experience any of these symptoms, you should stop taking allopurinol and seek medical attention immediately.

It is important to note that this is not a comprehensive list of side effects, and you should always talk to your doctor if you have any concerns about the medication you are taking.

Answers to Common Inquiries about Allopurinol Tablets

Q1. Can Allopurinol tablets be taken on an empty stomach?

Answer: Yes, Allopurinol can be taken with or without food. However, to reduce the risk of stomach upset, taking it with food or after a meal is recommended.

Q2. Is Allopurinol safe for children with hyperuricemia?

Answer: Allopurinol is generally not recommended for children with hyperuricemia. Its use in pediatric patients is limited and requires careful consideration by a healthcare provider due to potential risks and lack of sufficient data.

Q3. Can Allopurinol be used for acute gout attacks?

Answer: Allopurinol is not suitable for treating acute gout attacks. It's intended for long-term management and prevention of gout by reducing uric acid levels. Acute gout attacks are typically treated with anti-inflammatory medications.

Q4. Are there any dietary restrictions while taking Allopurinol?

Answer: While there are no strict dietary restrictions, consuming excessive amounts of alcohol, high-purine foods (e.g., organ meats, shellfish), and sugary beverages may impact the effectiveness of Allopurinol. A balanced diet and staying hydrated are generally advised.

Q5. Can Allopurinol be discontinued once uric acid levels normalize?

Answer: No, Allopurinol should not be abruptly stopped once uric acid levels are controlled. Stopping the medication suddenly can lead to a resurgence of gout symptoms and increased uric acid levels. Consult a healthcare provider before making any changes to the treatment plan.

Zyloprim/Zyrik (Allopurinol) may interact with other medications, including:

  1. Azathioprine: Zyrik may increase the toxicity of azathioprine.

  2. Warfarin: Zyrik may increase the anticoagulant effect of warfarin, increasing the risk of bleeding.

  3. Diuretics: Zyrik may interact with diuretics such as hydrochlorothiazide, increasing the risk of hypersensitivity reactions.

  4. Mercaptopurine: Zyrik may increase the toxicity of mercaptopurine.

  5. Theophylline: Zyrik may increase the concentration of theophylline in the blood, increasing the risk of side effects.

  6. Ampicillin or amoxicillin: Zyrik may increase the risk of rash in individuals taking these antibiotics.

  7. Cyclophosphamide or doxorubicin: Zyrik may increase the toxicity of these medications.

It's important to inform a healthcare professional of all medications being taken, including over-the-counter drugs, herbal remedies, and supplements before starting Zyrik. Additionally, it's important to monitor for any potential side effects or interactions while taking Zyrik. A healthcare professional should be consulted if any concerns arise.

More Information Demo
Manufacturer : Cipla Pharma, India
Equivalent Brand : Zyloprim
Generic Search : Allopurinol