Acamprol Tablet (Acamprosate)
Acamprol Tablet (Acamprosate 333 mg) helps support individuals in maintaining abstinence from alcohol dependence. Acamprol, also knowns as Campral, contains Acamprosate, an active ingredient that helps restore the chemical balance in the brain affected by long-term alcohol use. Acamprol is usually taken alongside counseling and support programs to improve recovery outcomes. The usual adult dose of Acamprol 333 mg (Acamprosate / Campral) is two tablets taken three times daily as per Doctor's prescription.
Introduction
Acamprol 333 mg contains Acamprosate, an FDA approved medication used to support recovery from alcohol dependence. The medication is generally used with counseling and therapy, Acamprol helps maintain long-term abstinence and reduce the risk of relapse in individuals who have already stopped drinking. Also known as Campral, It works by restoring the natural balance of brain chemicals disrupted by chronic alcohol use.
Acamprosate works as a synthetic amino acid and neurotransmitter regulator. It stabilizes key brain chemicals such as GABA (gamma-aminobutyric acid) and glutamate which helps the brain return to normal functioning in people recovering from alcohol dependence.
Acamprosate precautions
Here are the key precautions for Acamprosate (Acamprol 333 mg) that patients and healthcare providers typically consider:
Kidney Problems
Acamprosate is cleared through the kidneys.
Not recommended in severe kidney impairment
Dose adjustment may be needed in moderate kidney disease
Always inform your doctor if you have kidney issues.
Liver Disease
Unlike some alcohol-dependence medicines, Acamprosate is not processed by the liver, making it safer than alternatives in liver disease. However, your doctor should still review your medical history.
Pregnancy & Breastfeeding
Discuss with your doctor before starting treatment and use only if the potential benefit outweighs the risk
Depression or Suicidal Thoughts
Some people may experience mood changes, anxiety, or suicidal thoughts.
Seek medical help immediately if symptoms worsen.
Allergy
Avoid Acamprosate if you are allergic to Acamprosate calcium or any inactive ingredient in the tablet.
Children & Adolescents
Not recommended for patients under 18 years of age.
Continue Counseling
Acamprosate works best with psychological support, therapy, or rehabilitation programs, not as a standalone treatment.
Not for Active Alcohol Withdrawal
It is usually prescribed to person who has already stopped drinking.
It does not treat withdrawal symptoms like tremors or seizures.
Medication Interactions
Generally has few interactions, but always inform your doctor about:
Other prescriptions
OTC drugs
Vitamins or supplements
Adherence
It must be taken prescribed on regular basis, even if cravings decrease.
Contact your doctor/Healthcare provider if you notice:
Severe diarrhea
Mood or behavior changes
Signs of allergic reaction
Worsening depression or anxiety
Usage of Acamprol Tablet (Acamprosate 333 mg)
Acamprosate is used to support recovery from alcohol dependence.
Helps reduce alcohol cravings and supports long-term abstinence.
Recommended only after stopping alcohol completely.
Works best when combined with counseling, therapy, or rehabilitation programs.
Intended for adult patients recovering from alcoholism.
Treatment should always be taken exactly as prescribed by your doctor.
Do not stop Acamprol suddenly without medical advice.
Side Effects of Acamprol Tablet (Acamprosate 333 mg)
Like all medicines, Acamprol 333 mg (Acamprosate) may cause some side effects in certain individuals. Most side effects are mild and improve as your body adjusts to the medicine.
Common Side Effects
Diarrhea
Nausea or vomiting
Stomach discomfort
Loss of appetite
Gas or bloating
Headache
Dizziness or tiredness
Trouble sleeping
Anxiety or nervousness
Muscle or joint pain
Less Common / Rare Side Effects
Skin rash or itching
Mood changes
Depression or irritability
Seek Medical Help Immediately If You Notice
Severe diarrhea or dehydration
Suicidal thoughts or behavior changes
Signs of an allergic reaction (swelling, rash, difficulty breathing)
Important Note
Most people tolerate Acamprol (Campral) well, especially when taken as prescribed. Always inform your doctor if any side effects persist or worsen.
Frequently asked Questions (FAQs)
Q: Can Acamprol Tablet (Acamprosate) be used for opioid addiction?
A: No. Acamprol (Acamprosate) is not effective for opioid addiction treatment as it is specifically prescribed to support recovery from alcohol dependence. It should only be used as advised by a healthcare professional.
Q: What is the recommended duration of Acamprol 333 mg treatment?
A: The duration of Acamprol 333 mg (Acamprosate) treatment varies based on the individual and their recovery plan. Most patients continue therapy for several months or longer. It is advised to always follow your doctor’s prescribed course for best results in maintaining alcohol abstinence.
Q: Can Acamprol (Acamprosate) be taken with other medications?
A: Yes, but you should inform your doctor about all medications and supplements you are taking before starting Acamprol. This helps prevent potential interactions and ensures safe treatment.
Q: Is Acamprol Tablet habit-forming?
A: No. Acamprol (Acamprosate 333 mg) is not habit-forming and does not cause dependence when used as directed under medical supervision.
Q: Can Acamprol Tablet be used by individuals with liver problems?
A: Acamprol (Campral) is generally considered safer than many alternatives in people with liver problems because it is not metabolized by the liver. However, your doctor will still assess your overall health especially kidney function before prescribing it.
Acamprosate Interactions:
Kidney-Affecting Medicines
Because Acamprosate is eliminated via the kidneys, use caution with drugs that may affect kidney function, such as:
Nonsteroidal anti-inflammatory drugs (NSAIDs): While Short term use is fine, long term use can decrease renal blood flow which could slow the clearance of Acamprosate.
Certain antibiotics, such as:
Aminoglycosides (e.g., gentamicin, amikacin)
Vancomycin
High-dose or prolonged cephalosporins
Some antivirals used for serious infections
Diuretics (“water pills”)
Kidney function may need monitoring.
Although not a direct interaction, combining Acamprosate with medicines that affect the brain may increase:
Drowsiness
Dizziness
Confusion (rare)
Examples include:
Benzodiazepines (diazepam, lorazepam)
Sedatives or sleep aids
Antipsychotics
Antiepileptic Medicines
No strong interaction is known, but monitoring is advised with:
Gabapentin
Carbamazepine
Valproate
Herbal / Supplement Interactions (Use Caution)
Kava
Valerian
St. John’s Wort
These may increase sedation or affect mood.
Note:- Avoid if allergic to Acamprosate calcium or tablet components.
| Manufacturer | : | Sun Pharma, India |
| Equivalent Brand | : | Campral |
| Generic Search | : | Acamprosate |








