Duzela M Capsule DR (Duloxetine + Methylcobalamin)

Duzela M is a combination medication that contains two active ingredients: Duloxetine and Methylcobalamin. Duloxetine belongs to a class of drugs called selective serotonin and norepinephrine reuptake inhibitors (SNRIs), which are commonly used to treat depression and anxiety disorders.

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Duzela M 20 Capsule DR (Duloxetine (20mg) + Methylcobalamin (1.5mg))

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30 Tablet/s $14.50
60 Tablet/s $29.00
90 Tablet/s $43.50

Duzela M 30 Capsule DR (Duloxetine (30mg) + Methylcobalamin (1.5mg))

Package QTY Price Add To Cart
30 Tablet/s $18.90
60 Tablet/s $37.80
90 Tablet/s $56.70


Introduction: Duloxetine + Methylcobalamin Capsule (Duzela M)

Duzela M is a pharmaceutical product that combines two key ingredients: Duloxetine and Methylcobalamin. This combination offers a comprehensive approach to addressing certain medical conditions, providing both antidepressant and neurological benefits. The Duloxetine Methylcobalamin capsule contains 20 mg of duloxetine and 12.5mg Methylcobalamin of a potent antidepressant commonly known as Cymbalta, along with methylcobalamin, which plays a crucial role in nerve health. One of the primary components of Duzela M is duloxetine, a medication that belongs to the class of drugs called selective serotonin and norepinephrine reuptake inhibitors (SNRIs). Duloxetine is widely recognized for its effectiveness in managing depressive disorders, anxiety, and other mood-related conditions. By regulating the levels of serotonin and norepinephrine in the brain, duloxetine helps restore emotional balance and alleviate symptoms of depression.

Cymbalta Antidepressant:
Cymbalta is the brand name of duloxetine, which is well-established in the medical field as an effective antidepressant. It is approved by regulatory authorities for treating major depressive disorder, generalized anxiety disorder, fibromyalgia, diabetic peripheral neuropathy, and chronic musculoskeletal pain, among other conditions. Cymbalta works by blocking the reabsorption of serotonin and norepinephrine in the brain, increasing their availability and enhancing mood regulation.

Cymbalta Medication:
Cymbalta, or duloxetine, is a prescription medication that should be taken as directed by a healthcare professional. The recommended dosage of duloxetine in Duzela M capsules is 60 mg, but individual dosages may vary depending on the specific condition being treated and the patient's response to the medication. It is essential to follow the prescribed dosage and duration of treatment for optimal results. Duzela M capsules, containing 60 mg of duloxetine, are an effective combination of duloxetine and methylcobalamin. Duloxetine, also known as Cymbalta, is a widely used antidepressant with proven efficacy in managing depression, anxiety, and certain pain conditions. With the added benefits of methylcobalamin, Duzela M offers a comprehensive approach to addressing both mental health and neurological well-being. It is crucial to consult with a healthcare professional before starting or modifying any medication regimen, including Duzela M.

Related Article: Recommended Treatment for Depression and Nerve Pain with Cymbalta

Dose Information of Duloxetine + Methylcobalamin Capsule (Duzela M)

The dosage of Duloxetine + Methylcobalamin Capsule (Duzela M) may vary depending on the individual's condition and the prescribing doctor's instructions. It is important to follow the recommended dosage provided by your healthcare professional. The usual dosage information for Duzela M is as follows:

For Duloxetine:

The typical starting dose for adults is 30 milligrams (mg) once daily.

Depending on the individual's response and tolerability, the dose may be increased to a maximum of 60 mg once daily.

For Methylcobalamin:

The usual recommended dose of Methylcobalamin is 1500 micrograms (mcg) once daily.
It is important to take the medication as prescribed and at the recommended times. Do not exceed the prescribed dosage without consulting your doctor. If you have any concerns or questions regarding the dosage of Duzela M, it is best to consult with your healthcare provider for personalized advice. They will consider your specific medical condition and make appropriate dosage adjustments if necessary.

Duzela M capsules should be taken orally with water, preferably with or without food, as instructed by your doctor. Swallow the capsule whole and do not crush or chew it unless otherwise directed by your healthcare professional.

Follow-up Consultations:
It is important to have regular follow-up consultations with your doctor while taking Duzela M. They will monitor your progress, assess the medication's effectiveness, and make any necessary adjustments to the dosage or treatment plan.

Adherence to the Prescription:
To ensure optimal results and minimize the risk of adverse effects, it is crucial to follow the prescribed dosage and schedule of Duzela M as instructed by your healthcare provider. Do not stop taking the medication abruptly or make any changes without consulting your doctor. Remember, the dosage and treatment duration of Duzela M may vary for different individuals, so it is important to consult your healthcare professional for personalized advice and guidance regarding your specific medical condition.

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Must Alter  While Using Duloxetine + Methylcobalamin Capsule (Duzela M)

When using Duloxetine + Methylcobalamin Capsule (Duzela M), it is important to take certain precautions to ensure the safe and effective use of the medication. Here are some precautions to consider:

Medical History: Inform your healthcare provider about your complete medical history, especially if you have a history of liver or kidney problems, seizures, bipolar disorder, glaucoma, bleeding disorders, or any other significant medical conditions. This information will help your doctor assess the suitability of Duzela M for you.

Allergies: Inform your doctor about any known allergies or hypersensitivity to duloxetine, methylcobalamin, or any other ingredients present in Duzela M capsules. Allergic reactions to medications can range from mild to severe, so it is important to disclose this information to your healthcare provider.

Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using Duzela M with your healthcare provider. The safety of duloxetine and methylcobalamin during pregnancy and breastfeeding is not well-established, and your doctor will help you make an informed decision.

Suicidal Thoughts and Behavior: Like other antidepressants, duloxetine may increase the risk of suicidal thoughts and behavior, particularly in individuals under the age of 25. If you experience any worsening of depression, unusual changes in mood or behavior, or have suicidal thoughts, immediately seek medical assistance.

Withdrawal Symptoms: Abruptly stopping or significantly reducing the dose of duloxetine may result in withdrawal symptoms such as dizziness, nausea, headache, irritability, insomnia, or flu-like symptoms. Consult your doctor for guidance on gradually tapering off the medication, if necessary.

Alcohol Consumption: Avoid excessive alcohol consumption while taking Duzela M, as it may increase the risk of certain side effects such as drowsiness, dizziness, or impaired judgment.

Driving and Operating Machinery: Duloxetine can cause drowsiness, dizziness, or blurred vision. If you experience these effects, avoid driving or operating machinery until you know how the medication affects you.

Some Of The Applications of Duloxetine + Methylcobalamin Capsule (Duzela M):

Depression: Duzela M is used to treat major depressive disorder, helping to alleviate symptoms such as persistent sadness, loss of interest, and changes in appetite or sleep patterns.

Anxiety Disorders: Duzela M is prescribed for various anxiety disorders, including generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic disorder, to reduce excessive worry, fear, and anxiety symptoms.

Related Article: Medications to treat anxiety and mood disorders

Neuropathic Pain: Duzela M is effective in managing neuropathic pain conditions, including diabetic peripheral neuropathy, which causes tingling, numbness, and burning sensations in the hands and feet.

Fibromyalgia: Duzela M is used as a treatment option for fibromyalgia, a chronic pain disorder characterized by widespread musculoskeletal pain, fatigue, and tenderness in specific areas.

Chronic Musculoskeletal Pain: Duzela M may be prescribed for chronic musculoskeletal pain conditions, such as chronic lower back pain or osteoarthritis, to help reduce pain and improve quality of life.

Nerve Health: The presence of methylcobalamin in Duzela M supports nerve health and can benefit individuals with neurological conditions, including peripheral neuropathy and neuropathic pain.

Key After Effects of Using Duloxetine + Methylcobalamin Capsule (Duzela M):

Duloxetine + Methylcobalamin Capsule (Duzela M) may cause certain side effects in some individuals. While not everyone experiences these side effects, it is important to be aware of them. If you notice any persistent or severe side effects, it is recommended to seek medical attention. Here are some potential side effects associated with Duzela M:

Nausea: One of the common side effects of Duzela M is nausea, which may range from mild discomfort to persistent feelings of queasiness.

Headache: Some individuals may experience headaches as a side effect of Duzela M. These headaches can vary in intensity and duration.

Dry mouth: Duzela M can cause a dry sensation in the mouth, which may be accompanied by increased thirst.

Dizziness: Dizziness or lightheadedness may occur in some individuals taking Duzela M. It is advisable to avoid activities that require alertness until the dizziness subsides.

Fatigue: Feeling tired or experiencing fatigue is a possible side effect of Duzela M. It is important to get adequate rest while taking this medication.

Insomnia: In some cases, Duzela M may cause difficulty in falling asleep or staying asleep, leading to insomnia.

Constipation: Duzela M can lead to constipation in certain individuals. Maintaining a healthy diet and drinking plenty of fluids can help alleviate this side effect.

Sweating: Increased sweating, including excessive sweating or night sweats, may occur as a side effect of Duzela M.

Sexual Dysfunction: Some individuals may experience sexual side effects, such as decreased libido, difficulty achieving orgasm, or erectile dysfunction.

Increased Blood Pressure: Duzela M may occasionally cause an increase in blood pressure. Regular monitoring of blood pressure is advised, especially for individuals with pre-existing hypertension.

Serotonin Syndrome: Although rare, excessive serotonin levels can cause a potentially life-threatening condition called serotonin syndrome. Seek immediate medical attention if you experience symptoms such as agitation, hallucinations, rapid heartbeat, fever, muscle stiffness, or tremors.

Help Section - Duzela M Capsule DR (Duloxetine + Methylcobalamin)

Can Duzela M cause weight gain?

Weight gain is a possible side effect of Duzela M. While not everyone experiences this side effect, some individuals may notice an increase in weight. It is important to maintain a healthy lifestyle, including regular exercise and a balanced diet, to manage weight while taking this medication.

How long does it take for Duzela M to start working?

The onset of therapeutic effects may vary among individuals. In some cases, it may take a few weeks for Duzela M to start showing noticeable improvements in symptoms. It is important to continue taking the medication as prescribed and consult your healthcare provider if you have any concerns about its effectiveness.

Can Duzela M be taken with food?

Duzela M can be taken with or without food, as directed by your healthcare provider. However, taking it with food may help reduce the likelihood of experiencing stomach discomfort or nausea. Follow the instructions provided by your doctor or on the prescription label regarding the administration of Duzela M.

Are there any withdrawal symptoms when stopping Duzela M?

Abruptly stopping Duzela M may result in withdrawal symptoms. It is recommended to gradually reduce the dosage under the guidance of your healthcare provider to minimize the risk of withdrawal effects. Symptoms such as dizziness, nausea, headache, irritability, or flu-like symptoms may occur when discontinuing the medication, especially after long-term use.

Can I drink alcohol while taking Duzela M?

It is generally advisable to avoid or limit alcohol consumption while taking Duzela M. Alcohol can enhance the sedative effects of the medication and may increase the risk of side effects such as drowsiness, dizziness, or impaired judgment. It is recommended to consult your healthcare provider regarding alcohol consumption and its potential interactions with Duzela M.

Drug Interactions with Duloxetine + Methylcobalamin Capsule (Duzela M)

When taking Duloxetine + Methylcobalamin Capsule (Duzela M), it is important to be aware of potential drug interactions. Interactions can occur when certain medications are taken together, leading to changes in effectiveness, side effects, or potential health risks. Here are some key points regarding drug interactions with Duzela M:

Monoamine Oxidase Inhibitors (MAOIs): Avoid using Duzela M within 14 days of stopping an MAOI medication. Combining these drugs can lead to a potentially life-threatening condition known as serotonin syndrome.

Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs): Concurrent use of Duzela M with other SSRIs or SNRIs can increase the risk of serotonin syndrome. Close monitoring is essential if combination therapy is necessary.

Blood Thinners (Anticoagulants): Duzela M may increase the risk of bleeding when used with anticoagulant medications such as warfarin or heparin. Regular monitoring of blood clotting parameters is crucial.

Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Combining Duzela M with NSAIDs, such as ibuprofen or naproxen, may increase the risk of bleeding in the gastrointestinal tract. Caution should be exercised, and any signs of bleeding should be promptly reported to a healthcare professional.

Central Nervous System Depressants: Duzela M can enhance the sedative effects of other medications that act on the central nervous system, such as benzodiazepines, opioids, or alcohol. Avoid or use caution when combining these medications to prevent excessive sedation.

CYP1A2 Inhibitors: Certain medications that inhibit the enzyme CYP1A2, such as fluvoxamine or ciprofloxacin, can increase the levels of duloxetine in the body. Dosage adjustments may be necessary when using Duzela M with these medications.

CYP2D6 Inhibitors and Poor Metabolizers: Some medications that inhibit or are metabolized by the CYP2D6 enzyme, such as fluoxetine or quinidine, can affect the metabolism and effectiveness of duloxetine. Dose adjustments may be required in such cases.

Other Medications: Inform your healthcare provider about all medications, including prescription, over-the-counter, and herbal supplements, that you are taking. They can assess potential interactions and adjust your treatment plan accordingly.

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Manufacturer : Sun Pharma, India
Equivalent Brand : Duloxetine + Methylcobalamin
Generic Search : Duloxetine + Methylcobalamin