Espra XN Tablet (Naproxen + Esomeprazole) | For Pain, Inflammation Management with Gastric Protection
Espra XN Tablet is a combination medicine containing naproxen 375 mg and esomeprazole 20 mg. It is used to help relieve pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It may also be used for certain muscle, back, tooth, ear, or throat pain. Naproxen helps reduce pain and inflammation, while esomeprazole reduces stomach acid and helps protect the stomach during treatment.
Product Overview
Espra XN Tablet is a combination medicine containing naproxen and esomeprazole. It is designed to provide relief from pain and inflammation while also reducing the production of stomach acid. The combination can be useful when an anti-inflammatory medicine is needed and there is a need to reduce the risk of stomach irritation associated with NSAID treatment.
Composition
Naproxen 375 mg – a non-steroidal anti-inflammatory medicine that helps reduce pain, swelling, and inflammation.
Esomeprazole 20 mg – a proton pump inhibitor that reduces stomach acid production.
How It Works
Naproxen works by reducing the formation of substances called prostaglandins that contribute to pain, inflammation, and swelling. Esomeprazole reduces stomach acid by blocking the acid-producing proton pump in stomach cells. Together, these ingredients provide pain and inflammation management while helping reduce acid-related stomach irritation.
Uses
Espra XN Tablet may be used in the management of pain and inflammation associated with conditions such as:
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Certain musculoskeletal conditions
Other inflammatory pain conditions when considered appropriate
Important Information
Espra XN Tablet should be taken according to the recommended instructions. It is generally taken with food or as directed to reduce stomach discomfort. The tablet should be swallowed whole with water rather than crushed or chewed.
Because naproxen can affect the stomach, kidneys, heart, and blood pressure, extra care may be needed in people with a history of stomach ulcers, gastrointestinal bleeding, kidney disease, heart disease, or high blood pressure. Long-term or unnecessary use of NSAIDs should be avoided.
Possible side effects can include indigestion, stomach discomfort, nausea, vomiting, dizziness, headache, diarrhea, or constipation. Serious stomach bleeding, severe allergic reactions, breathing difficulty, or unusual swelling require prompt medical attention.
If other medicines are being used, particularly blood thinners, other pain-relieving NSAIDs, corticosteroids, or medicines affecting kidney function, professional guidance is important before using this combination.
- Take Espra XN Tablet only as directed and avoid using more than the recommended dose.
- Inform your healthcare professional if you have a history of stomach ulcers, gastrointestinal bleeding, or severe acidity-related problems.
- Use with caution if you have kidney, liver, or heart problems, high blood pressure, or fluid retention.
- Tell your healthcare professional if you have asthma or have previously experienced breathing problems or allergic reactions after using pain-relieving medicines.
- Avoid taking Espra XN Tablet together with other NSAID pain relievers unless specifically advised, as this may increase the risk of stomach and other side effects.
- Inform your healthcare professional about blood thinners, corticosteroids, blood-pressure medicines, or other regular medicines you are taking.
- Avoid excessive alcohol consumption because it may increase the risk of stomach irritation and bleeding.
- Older adults may be more sensitive to certain side effects and may require closer monitoring.
- If you develop black stools, vomiting blood, severe stomach pain, facial swelling, breathing difficulty, or a serious skin reaction, seek immediate medical attention.
- Do not use this medicine for longer than recommended without professional guidance.
Usage
Espra XN Tablet is used to manage pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and certain musculoskeletal problems. It combines naproxen, which helps reduce pain and inflammation, with esomeprazole, which lowers stomach acid.
- Take Espra XN Tablet exactly as directed by your healthcare professional.
- Swallow the tablet whole with water; do not crush, chew, or break it.
- It is generally taken with or after food to help reduce stomach discomfort.
- Take it at the recommended time and avoid taking more than the advised dose.
- Do not combine it with other NSAID pain relievers unless specifically advised.
- If you miss a dose, take it when remembered unless it is nearly time for the next dose. Do not take two doses together.
- Use it for the recommended duration and avoid prolonged use without professional guidance.
- If you experience severe stomach pain, black stools, vomiting blood, breathing difficulty, or facial swelling, seek medical attention promptly.
Uses
Espra XN Tablet contains naproxen and esomeprazole. It is mainly used to manage pain and inflammation while reducing stomach acid.
- Osteoarthritis: Helps relieve joint pain, swelling, and stiffness.
- Rheumatoid arthritis: Helps reduce inflammation and associated joint pain.
- Ankylosing spondylitis: May help manage pain and inflammation affecting the spine and joints.
- Musculoskeletal pain: Can be used for certain muscle, joint, or other inflammatory pain conditions.
- Pain associated with inflammation: Naproxen helps reduce inflammatory pain, while esomeprazole helps reduce stomach acid and protect against acid-related irritation during treatment.
Side Effects
Espra XN Tablet contains naproxen and esomeprazole. Some people may experience side effects, particularly during the initial period of treatment.
Common
- Nausea or vomiting
- Indigestion or heartburn
- Stomach discomfort or abdominal pain
- Diarrhea or constipation
- Headache
- Dizziness
- Gas or bloating
- Tiredness
Less Common Effects
- Changes in blood pressure
- Swelling of the hands, feet, or ankles
- Skin rash or itching
- Changes in kidney function
- Changes in liver function
FAQs
What is Espra XN Tablet used for?
Espra XN Tablet is used to relieve pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and other inflammatory or musculoskeletal conditions.
What does Espra XN Tablet contain?
It contains naproxen 375 mg and esomeprazole 20 mg.
How does Espra XN Tablet work?
Naproxen helps reduce pain and inflammation, while esomeprazole decreases stomach acid and helps reduce acid-related stomach irritation.
Can Espra XN Tablet cause stomach problems?
Yes. It may cause indigestion, stomach discomfort, nausea, or other digestive effects. Contact a healthcare professional if severe stomach pain or signs of bleeding occur.
Can I take other painkillers with Espra XN Tablet?
Avoid taking other NSAID painkillers unless advised, as combining them can increase the risk of stomach irritation, ulcers, bleeding, and other side effects.
Can Espra XN Tablet be taken for a long time?
Long-term use should be based on professional guidance because naproxen may affect the stomach, kidneys, cardiovascular system, and other organs with prolonged use.
Can alcohol be consumed with Espra XN Tablet?
Alcohol may increase stomach irritation and the risk of gastrointestinal bleeding, so limiting or avoiding alcohol is advisable.
What are the common side effects of Espra XN Tablet?
Possible side effects include nausea, indigestion, stomach discomfort, headache, dizziness, diarrhea, and constipation.
Espra XN Tablet contains naproxen and esomeprazole, so it can interact with medicines that affect pain, blood clotting, stomach acid, kidney function, and blood pressure.
- Other NSAIDs: Combining naproxen with medicines such as ibuprofen, diclofenac, or aspirin for pain may increase the risk of stomach irritation, ulcers, and bleeding.
- Blood thinners: Medicines such as warfarin and other anticoagulants may increase the risk of bleeding when used with naproxen.
- Antiplatelet medicines: Medicines such as clopidogrel may increase bleeding risk when combined with naproxen.
- Corticosteroids: Medicines such as prednisolone may increase the risk of stomach ulcers and gastrointestinal bleeding.
- Blood-pressure medicines: ACE inhibitors, ARBs, beta-blockers, and some diuretics may have reduced effects, while NSAIDs can also affect kidney function.
- Methotrexate: Naproxen may increase methotrexate exposure and the risk of adverse effects.
- Lithium: Naproxen can increase lithium levels in the blood and may raise the risk of lithium-related side effects.
- Digoxin: Naproxen may increase digoxin levels, requiring appropriate monitoring.
- Medicines affected by stomach acid: Esomeprazole changes stomach acidity and can affect the absorption of certain medicines.
| Manufacturer | : | Zydus Healthcare Ltd |
| Equivalent Brand | : | Vimovo |
| Generic Search | : | Naproxen + Esomeprazole |
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