Fliban Tablet (Flibanserin)
Fliban Tablet (Flibanserin) is an oral medication which is used for the treatment of hypoactive sexual desire disorder (HSDD) in women who are not in menopause. It does so through the modification of specific neurotransmitters within the brain, thereby helping to balance the various hormones, including dopamine and serotonin, that play a role in sexual desire.
Product Overview
The drug Fliban Tablet is an orally administered that contains the active ingredient Flibanserin, and its primary use includes the treatment of Hypoactive Sexual Desire Disorder (HSDD) in premenopausal females. Flibanserin affects neurotransmitters in the brain to facilitate the enhancement of sexual arousal among patients who have been properly diagnosed with HSDD.
Flibanserin differs from hormonal therapy drugs since it affects neurotransmitter activity in the brain such as serotonin and dopamine.
Pharmacological Profile
| Parameter | Details |
| Active Ingredient | Flibanserin |
| Drug Class | Serotonin receptor modulator / CNS-acting agent |
| Dosage Form | Oral Tablet |
| Target Condition | Hypoactive Sexual Desire Disorder (HSDD) in premenopausal women |
| Mechanism Type | Neurotransmitter modulation |
Mechanism of Action (How It Works)
Neurotransmitters Regulation
Flibanserin acts on certain neurotransmitters that affect sexual libido:
- Inhibits excess activation of serotonin receptors (may cause lack of libido)
- Increases dopamine concentration (responsible for the sense of reward)
- Stimulates norepinephrine activation (increases libido)
Effects on the Central Nervous System
Central Nervous System Action
- Flibanserin acts on certain brain zones responsible for the sexual response, bringing back the balance in the corresponding neural transmission processes.
Slow-Effecting Drug
- Unlike other medications, the effect of this remedy develops slowly over time with regular usage.
Administration Instructions
- To be taken once a day at night
- Do not take alcoholic beverages as it may lead to hypotension and unconsciousness
- Take as directed by the healthcare practitioner
- Should not be used right before sexual intercourse as needed
- It may take a few weeks before seeing its effects
Precautions:
Fliban Tablet (Flibanserin) should be used only under proper medical supervision, as it affects central nervous system neurotransmitters and may cause significant side effects if not used correctly. Careful evaluation is required before starting therapy, especially in patients with other medical conditions or concurrent medications.
General Precautions
- Use strictly as prescribed by a qualified healthcare professional
- Not intended for use in men or postmenopausal women
- Avoid self-medication or dose adjustment without medical advice
- Take only the recommended dose; do not exceed prescribed duration
- May cause dizziness, sleepiness, or low blood pressure—use caution during activities requiring alertness (e.g., driving)
Alcohol Interaction Warning
- Avoid alcohol completely during treatment
- Concomitant use with alcohol may lead to severe hypotension, fainting, and loss of consciousness
- Even small amounts of alcohol can increase risk of serious adverse reactions
Liver Function Considerations
- Flibanserin is extensively metabolized in the liver
- Not recommended in patients with liver impairment
- Use with caution in individuals with a history of liver disease
- Discontinue immediately if symptoms of liver dysfunction occur (fatigue, jaundice, dark urine)
Drug Interaction Precautions
- Avoid use with strong CYP3A4 inhibitors (e.g., certain antifungals, antibiotics, and antivirals)
- Caution when used with medications that cause drowsiness or CNS depression
- Inform your doctor about all prescription, OTC, and herbal medicines before starting treatment
Pregnancy & Breastfeeding
- Not recommended during pregnancy unless clearly advised by a doctor
- Safety data in pregnancy is limited
- Breastfeeding should be avoided during treatment unless medically necessary
- Always consult a healthcare provider before use in these conditions
Safety & Lifestyle Precautions
- Avoid driving or operating heavy machinery if dizziness or drowsiness occurs
- Maintain regular follow-ups if therapy is continued long-term
- Report any unusual mood changes, severe fatigue, or fainting episodes to a doctor immediately
Usage
General Usage Information
Fliban Tablet (Flibanserin) is used as a prescription medicine for the management of hypoactive sexual desire disorder (HSDD) in premenopausal women. It works by acting on certain neurotransmitters in the brain to help improve sexual desire over time. The effectiveness of treatment depends on regular use, correct dosing, and adherence to safety guidelines provided by a healthcare professional.
Key Usage Points
✔ Take the medicine exactly as prescribed by a healthcare professional
✔ Usually taken once daily at bedtime to reduce side effects like dizziness
✔ May take several weeks to show noticeable improvement
✔ Avoid alcohol while using this medicine due to risk of severe hypotension or fainting
✔ Do not exceed the recommended dose
✔ Regular follow-up with a doctor is important to assess response
Uses
Fliban Tablet is primarily used for the treatment of acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. It is not intended for use in men or for enhancing sexual performance in healthy individuals.
How to Use
- Take orally with water, preferably at bedtime
- Swallow the tablet whole; do not crush or chew
- Take at the same time every day for consistent effect
- Follow the prescribed dose strictly based on medical advice
- Avoid grapefruit or grapefruit juice unless approved by your doctor
- Do not mix with alcohol or sedative medicines unless advised
Side Effects
General Safety Information
Fliban Tablet (Flibanserin) is generally used under medical supervision and is considered safe when taken as prescribed. However, it can affect the central nervous system and blood pressure, so side effects may occur in some individuals, especially during the initial period of treatment.
Common Side Effects
✔ Dizziness
✔ Drowsiness or sleepiness
✔ Nausea
✔ Fatigue or tiredness
✔ Dry mouth
✔ Difficulty sleeping (insomnia in some cases)
These effects are usually mild to moderate and may reduce as the body adjusts to the medicine.
Serious Side Effects (Rare but Important)
âš Seek medical attention immediately if you experience:
- Signs of low blood pressure (lightheadedness, fainting, blurred vision)
- Severe dizziness or loss of consciousness (syncope)
- Severe drowsiness or confusion
- Breathing difficulty or chest discomfort
- Allergic reactions (rash, itching, swelling of face/lips/tongue)
Alcohol Warning (Very Important)
Flibanserin should not be used with alcohol, as it can significantly increase the risk of severe low blood pressure, fainting, and excessive sedation.
Risk Factors & Monitoring
Higher risk of side effects in individuals who:
- Consume alcohol (strictly contraindicated)
- Have liver impairment
- Take other CNS depressants (sleeping pills, sedatives, some antidepressants)
- Are prone to low blood pressure
Doctors may recommend monitoring blood pressure and adjusting dosage if needed.
FAQs
What is Fliban Tablet used for?
Fliban Tablet (Flibanserin) is used to treat hypoactive sexual desire disorder (HSDD) in premenopausal women. It helps improve sexual desire and reduce distress related to low libido.
How does Fliban Tablet work in the body?
Flibanserin works by acting on certain brain chemicals such as serotonin, dopamine, and norepinephrine, which are involved in sexual desire. It helps restore balance in these neurotransmitters, thereby improving sexual interest over time.
Who can take Fliban Tablet?
It is generally prescribed for premenopausal women diagnosed with HSDD. It is not intended for men, postmenopausal women, or general enhancement of sexual performance without medical evaluation.
How should I take Fliban Tablet?
It should be taken exactly as prescribed by your doctor, usually once daily at bedtime. Taking it at night helps reduce the risk of side effects such as dizziness or low blood pressure. Avoid alcohol while using this medicine.
Interactions
General Interaction Overview
Fliban Tablet (Flibanserin) may interact with several medications and substances that affect the central nervous system or liver enzyme activity. These interactions can significantly change how the medicine works and may increase the risk of side effects such as dizziness, low blood pressure, or fainting. It is important to inform your healthcare provider about all medicines, supplements, and alcohol use before starting treatment.
Commonly Reported Interactions
Alcohol is strictly contraindicated as it may increase the risk of severe hypotension, fainting, and sedation
Strong CYP3A4 inhibitors such as ketoconazole, itraconazole, ritonavir, or clarithromycin may significantly increase drug levels and risk of side effects
Moderate CYP3A4 inhibitors like fluconazole, diltiazem, or verapamil may increase exposure and require caution or dose adjustment
| Manufacturer | : | Centurion Lab, India |
| Equivalent Brand | : | Addyi |
| Generic Search | : | Flibanserin |


























