Pirfeheal Tablet (Pirfenidone): Antifibrotic Tablet | For Idiopathic Pulmonary Fibrosis (IPF), Lung Fibrosis Management

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Pirfeheal Tablet contains Pirfenidone, an antifibrotic medicine used primarily in the treatment of idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases. It works by reducing lung fibrosis (scarring), inflammation, and the buildup of fibroblasts. It is commonly prescribed for long-term management in patients with progressive lung scarring conditions to improve breathing capacity.

Generic Pirfenidone 200mg (Pirfeheal 200mg)

Package	QTY	Price	Add To Cart
30 Tablet/s		$15.33
60 Tablet/s		$30.00
90 Tablet/s		$44.04

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Product Overview

Pirfeheal Tablet is an oral antifibrotic medication containing Pirfenidone, primarily used in the management of idiopathic pulmonary fibrosis (IPF) and other progressive fibrosing interstitial lung diseases. It works by slowing down the formation and progression of scar tissue in the lungs.

Pirfenidone is widely used in clinical practice as a disease-modifying therapy rather than a symptomatic relief drug. Its main role is to help preserve lung function over time and slow disease progression.

Mechanism Insights (How It Works)

Anti-fibrotic Activity
Pirfenidone reduces the production of fibrotic mediators, especially transforming growth factor-beta (TGF-β), which plays a key role in scar tissue formation in the lungs.
Anti-inflammatory Effect
It helps lower the release of inflammatory cytokines that contribute to ongoing lung tissue damage and fibrosis progression.
Reduction of Fibroblast Proliferation
The drug limits the activity and multiplication of fibroblasts, the cells responsible for producing excess collagen and scar tissue in the lungs.
Overall Outcome
By targeting multiple pathways involved in fibrosis, Pirfenidone helps slow down lung function decline and disease progression.

Administration Guidelines

Take exactly as prescribed by a healthcare professional
Usually administered with food to reduce gastric side effects
Dose is gradually titrated to minimize intolerance
Maintain consistent daily timing for stable drug levels
Avoid skipping doses for optimal therapeutic effect

Clinical Considerations

Used for long-term management, not acute symptom relief
Requires regular monitoring of liver function tests (LFTs)
Common side effects may include nausea, fatigue, rash, or loss of appetite
Sun sensitivity may occur; protective measures are recommended
Best outcomes seen with continuous, uninterrupted therapy
Not a cure, but helps slow progression of lung fibrosis
give storage requirementts for Pirfeheal Tablet (Pirfenidone)

Storage Requirements

Store Pirfeheal Tablets (Pirfenidone) at room temperature, preferably around 25°C.
Keep the tablets in their original packaging, protected from excess heat, light, and moisture.
Keep the container tightly closed when not in use.
Keep out of reach of children.
Do not use the tablets after the expiry date mentioned on the packaging.

Precautions

Pirfeheal Tablet (Pirfenidone) is used in the management of idiopathic pulmonary fibrosis (IPF) and should be taken under strict medical supervision. Careful monitoring is important to ensure safety and reduce the risk of adverse effects.

General Precautions

Use only as prescribed by a qualified healthcare professional.
Do not change the dose or stop the medicine without consulting your doctor.
Take the medication regularly for best therapeutic effect.
Inform your doctor about all existing medical conditions before starting treatment.
Avoid self-medication or sharing the medicine with others.

Liver Function Considerations

Pirfenidone is metabolized in the liver and may affect liver enzymes.

Use with caution in patients with pre-existing liver disease
Regular liver function tests (LFTs) may be required during treatment
Report symptoms such as yellowing of skin/eyes, dark urine, or persistent fatigue
Dose adjustment or discontinuation may be required if liver toxicity develops

Photosensitivity & Skin Protection

Pirfenidone can increase sensitivity to sunlight.

Avoid prolonged exposure to direct sunlight.
Use sunscreen (high SPF) and protective clothing when outdoors.
Avoid tanning beds or artificial UV exposure.
Report severe skin rash or sunburn-like reactions to your doctor.

Gastrointestinal Effects

Some patients may experience digestive discomfort.

Nausea, loss of appetite, indigestion, or vomiting may occur.
Taking the medicine with food can reduce stomach irritation.
Stay hydrated and report persistent GI symptoms.

Drug Interactions

Pirfenidone may interact with certain medicines.

Use caution with CYP1A2 inhibitors (e.g., fluvoxamine, ciprofloxacin).
Inform your doctor about all prescription, OTC, and herbal medicines.
Smoking may reduce drug effectiveness by increasing metabolism.

Pregnancy & Breastfeeding

Not recommended during pregnancy unless clearly advised by a doctor.
Women of childbearing age should use effective contraception during treatment.
Breastfeeding is not advised without medical consultation.

Respiratory Condition Monitoring

Regular follow-up is essential to monitor lung function.
Report worsening breathlessness or persistent cough immediately.
Do not stop treatment suddenly without medical advice.

Usage

General Usage Information

Pirfeheal Tablet (Pirfenidone) is an antifibrotic medicine used in the management of idiopathic pulmonary fibrosis (IPF) and other chronic lung conditions involving progressive scarring of lung tissue. It works by reducing inflammation and slowing down the formation of fibrotic (scar) tissue in the lungs.

The effectiveness of the treatment depends on regular dosing, long-term adherence, and proper monitoring under a healthcare professional.

Key Usage Points

✔ Take the medicine exactly as prescribed by your doctor
✔ Take it with food to reduce stomach irritation
✔ Swallow the tablet whole with water, do not crush or chew
✔ Maintain consistent timing each day for best results
✔ Do not stop the medicine suddenly without medical advice
✔ Regular liver function and lung monitoring may be required during treatment

Uses

irfeheal Tablet contains Pirfenidone, a medicine used to help manage idiopathic pulmonary fibrosis (IPF), a long-term lung condition in which scar tissue gradually develops and makes breathing more difficult.

Management of pulmonary fibrosis: Helps slow the progression of scarring in the lungs associated with IPF.
Supports lung function: May help preserve lung function by slowing the decline associated with the condition.
Helps manage disease progression: Works by affecting processes involved in inflammation and the formation of scar tissue.
Long-term treatment support: Regular use as prescribed may help manage the condition over time, although it does not reverse existing lung scarring.

Note: Take Pirfeheal Tablet consistently as prescribed and attend recommended follow-up appointments so your doctor can monitor your progress and liver function.

Side Effects

General Safety Information

Pirfenidone (Pirfeheal Tablet) is an antifibrotic medicine used in the treatment of idiopathic pulmonary fibrosis (IPF). It helps slow down the progression of lung scarring and supports better lung function over time.

Most side effects are mild to moderate and may improve as the body adjusts to the medicine, but regular monitoring is important during treatment.

Common Side Effects

✔ Nausea or vomiting
✔ Loss of appetite
✔ Indigestion or stomach discomfort
✔ Headache
✔ Dizziness
✔ Fatigue or weakness
✔ Skin rash or photosensitivity (increased sensitivity to sunlight)

These effects are usually temporary and can often be managed with dose adjustment or supportive care under medical guidance.

Serious Side Effects (Rare but Important)

⚠ Seek medical attention if you experience:

Signs of liver problems (yellowing of skin/eyes, dark urine, persistent fatigue)
Severe or persistent stomach pain
Significant weight loss
Severe skin reactions or sunburn-like rash
Shortness of breath worsening beyond usual condition
Allergic reactions (swelling, itching, difficulty breathing)

Risk Factors & Monitoring

Higher risk of side effects in patients with liver disease
Increased sensitivity to sunlight (sun protection is strongly recommended)
May require dose adjustment in long-term therapy
Regular liver function tests are usually recommended during treatment
Periodic monitoring of overall health status is important for safe long-term use

FAQs

1. What is Pirfeheal Tablet used for?

Pirfeheal Tablet contains pirfenidone, a medicine used to manage idiopathic pulmonary fibrosis (IPF), a long-term lung condition that causes scarring and makes breathing difficult.

2. How does Pirfeheal Tablet work?

Pirfenidone helps reduce the processes involved in lung scarring. It may slow the worsening of lung function over time but does not reverse existing lung damage.

3. How should I take Pirfeheal Tablet?

Take Pirfeheal Tablet exactly as prescribed by your doctor. It is generally taken with food to help reduce stomach-related side effects.

4. What are the common side effects of Pirfeheal Tablet?

Common side effects may include nausea, diarrhoea, indigestion, tiredness, reduced appetite, rash, and increased sensitivity to sunlight.

5. Can Pirfeheal Tablet cure pulmonary fibrosis?

No, Pirfeheal Tablet does not cure pulmonary fibrosis. It helps slow the progression of the disease and may help preserve lung function.

6. Why should I avoid direct sunlight while taking Pirfeheal Tablet?

Pirfenidone can make your skin more sensitive to sunlight, increasing the risk of sunburn and rashes. Use sunscreen, wear protective clothing, and limit direct sun exposure.

7. Can Pirfeheal Tablet affect the liver?

Yes, pirfenidone may increase liver enzyme levels and, in some cases, cause liver injury. Your doctor may recommend liver function tests before and during treatment.

8. Can I stop taking Pirfeheal Tablet if I feel better?

Do not stop or change your dose without consulting your doctor. Pulmonary fibrosis requires ongoing medical care, even when symptoms seem stable.

9. Can Pirfeheal Tablet be taken with other medicines?

Some medicines, including fluvoxamine and certain antibiotics, can interact with pirfenidone. Tell your doctor about all medicines, supplements, and herbal products you use.

10. What precautions should I follow while taking Pirfeheal Tablet?

Take it as prescribed, protect your skin from sunlight, attend recommended liver function tests, and report persistent nausea, loss of appetite, yellowing of the skin or eyes, or dark urine to your doctor promptly.

Interactions

General Interaction Overview

Pirfeheal Tablet (Pirfenidone) may interact with certain medicines that affect its metabolism or increase the risk of side effects, especially liver-related toxicity. These interactions can change how the drug works in the body, so it is important to inform your healthcare provider about all medicines you are using before starting treatment.

1. Certain Antibiotics

Medicines such as ciprofloxacin may increase pirfenidone levels and the risk of side effects.
Inform your doctor before taking antibiotics during treatment.

2. Smoking

Smoking may reduce pirfenidone levels and affect its effectiveness.
Avoid smoking and inform your healthcare provider if you smoke.

3. Other Medicines Affecting Liver Enzymes

Medicines such as fluvoxamine may increase pirfenidone levels in the body.
Tell your doctor about all medicines you take so interactions can be checked.

4. Other Medicines That Affect the Liver

Some medicines may increase the risk of liver-related side effects when taken with pirfenidone.
Inform your doctor about your current medicines and attend recommended liver function tests.

5. Food and Supplements

Taking pirfenidone with food can help reduce stomach-related side effects. Some supplements may also interact with your treatment.
Take Pirfeheal as prescribed and check with your doctor before starting supplements.

Tips to Avoid Interactions

Share your complete medicine and supplement list with your healthcare provider.
Do not start, stop, or change medicines without medical advice.
Attend recommended liver function tests during treatment.

Note: Not every combination causes a problem, but some may require monitoring or dose adjustments. Always follow your healthcare provider's advice.