Pirfeheal Tablet (Pirfenidone)

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Pirfeheal Tablet contains Pirfenidone, an antifibrotic medicine used primarily in the treatment of idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases. It works by reducing lung fibrosis (scarring), inflammation, and the buildup of fibroblasts, thereby helping to slow disease progression and preserve lung function. Pirfeheal is commonly prescribed for long-term management in patients with progressive lung scarring conditions to improve quality of life and breathing capacity.

Generic Pirfenidone 200mg (Pirfeheal 200mg)

Package	QTY	Price	Add To Cart
30 Tablet/s		$15.33
60 Tablet/s		$30.00
90 Tablet/s		$44.04

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Product Overview

Pirfeheal Tablet is an oral antifibrotic medication containing Pirfenidone, primarily used in the management of idiopathic pulmonary fibrosis (IPF) and other progressive fibrosing interstitial lung diseases. It works by slowing down the formation and progression of scar tissue in the lungs.

Pirfenidone is widely used in clinical practice as a disease-modifying therapy rather than a symptomatic relief drug. Its main role is to help preserve lung function over time and slow disease progression.

Mechanism Insights (How It Works)

Anti-fibrotic Activity
Pirfenidone reduces the production of fibrotic mediators, especially transforming growth factor-beta (TGF-β), which plays a key role in scar tissue formation in the lungs.
Anti-inflammatory Effect
It helps lower the release of inflammatory cytokines that contribute to ongoing lung tissue damage and fibrosis progression.
Reduction of Fibroblast Proliferation
The drug limits the activity and multiplication of fibroblasts, the cells responsible for producing excess collagen and scar tissue in the lungs.
Overall Outcome
By targeting multiple pathways involved in fibrosis, Pirfenidone helps slow down lung function decline and disease progression.

Administration Guidelines

Take exactly as prescribed by a healthcare professional
Usually administered with food to reduce gastric side effects
Dose is gradually titrated to minimize intolerance
Maintain consistent daily timing for stable drug levels
Avoid skipping doses for optimal therapeutic effect

Clinical Considerations

Used for long-term management, not acute symptom relief
Requires regular monitoring of liver function tests (LFTs)
Common side effects may include nausea, fatigue, rash, or loss of appetite
Sun sensitivity may occur; protective measures are recommended
Best outcomes seen with continuous, uninterrupted therapy
Not a cure, but helps slow progression of lung fibrosis

Precautions:

Pirfeheal Tablet (Pirfenidone) is used in the management of idiopathic pulmonary fibrosis (IPF) and should be taken under strict medical supervision. Careful monitoring is important to ensure safety and reduce the risk of adverse effects.

General Precautions

Use only as prescribed by a qualified healthcare professional
Do not change the dose or stop the medicine without consulting your doctor
Take the medication regularly for best therapeutic effect
Inform your doctor about all existing medical conditions before starting treatment
Avoid self-medication or sharing the medicine with others

Liver Function Considerations

Pirfenidone is metabolized in the liver and may affect liver enzymes.

Use with caution in patients with pre-existing liver disease
Regular liver function tests (LFTs) may be required during treatment
Report symptoms such as yellowing of skin/eyes, dark urine, or persistent fatigue
Dose adjustment or discontinuation may be required if liver toxicity develops

Photosensitivity & Skin Protection

Pirfenidone can increase sensitivity to sunlight.

Avoid prolonged exposure to direct sunlight
Use sunscreen (high SPF) and protective clothing when outdoors
Avoid tanning beds or artificial UV exposure
Report severe skin rash or sunburn-like reactions to your doctor

Gastrointestinal Effects

Some patients may experience digestive discomfort.

Nausea, loss of appetite, indigestion, or vomiting may occur
Taking the medicine with food can reduce stomach irritation
Stay hydrated and report persistent GI symptoms

Drug Interactions

Pirfenidone may interact with certain medicines.

Use caution with CYP1A2 inhibitors (e.g., fluvoxamine, ciprofloxacin)
Inform your doctor about all prescription, OTC, and herbal medicines
Smoking may reduce drug effectiveness by increasing metabolism

Pregnancy & Breastfeeding

Not recommended during pregnancy unless clearly advised by a doctor
Women of childbearing age should use effective contraception during treatment
Breastfeeding is not advised without medical consultation

Respiratory Condition Monitoring

Regular follow-up is essential to monitor lung function
Report worsening breathlessness or persistent cough immediately
Do not stop treatment suddenly without medical advice

Usage

General Usage Information

Pirfeheal Tablet (Pirfenidone) is an antifibrotic medicine used in the management of idiopathic pulmonary fibrosis (IPF) and other chronic lung conditions involving progressive scarring of lung tissue. It works by reducing inflammation and slowing down the formation of fibrotic (scar) tissue in the lungs.

The effectiveness of the treatment depends on regular dosing, long-term adherence, and proper monitoring under a healthcare professional.

Key Usage Points

✔ Take the medicine exactly as prescribed by your doctor
✔ Take it with food to reduce stomach irritation
✔ Swallow the tablet whole with water, do not crush or chew
✔ Maintain consistent timing each day for best results
✔ Do not stop the medicine suddenly without medical advice
✔ Regular liver function and lung monitoring may be required during treatment

Uses

Pirfeheal Tablet is primarily used in:

Idiopathic Pulmonary Fibrosis (IPF)
Other progressive fibrosing interstitial lung diseases (as advised by a specialist)

It helps slow disease progression and preserves lung function over time.

How to Use

Take orally with a full glass of water
Preferably take with meals to improve tolerance
Dosage is gradually adjusted based on medical supervision
Follow the prescribed schedule strictly for maximum benefit
Do not exceed or miss doses without consulting your doctor

Side Effects

General Safety Information

Pirfenidone (Pirfeheal Tablet) is an antifibrotic medicine used in the treatment of idiopathic pulmonary fibrosis (IPF). It helps slow down the progression of lung scarring and supports better lung function over time.

Most side effects are mild to moderate and may improve as the body adjusts to the medicine, but regular monitoring is important during treatment.

Common Side Effects

✔ Nausea or vomiting
✔ Loss of appetite
✔ Indigestion or stomach discomfort
✔ Headache
✔ Dizziness
✔ Fatigue or weakness
✔ Skin rash or photosensitivity (increased sensitivity to sunlight)

These effects are usually temporary and can often be managed with dose adjustment or supportive care under medical guidance.

Serious Side Effects (Rare but Important)

⚠ Seek medical attention if you experience:

Signs of liver problems (yellowing of skin/eyes, dark urine, persistent fatigue)
Severe or persistent stomach pain
Significant weight loss
Severe skin reactions or sunburn-like rash
Shortness of breath worsening beyond usual condition
Allergic reactions (swelling, itching, difficulty breathing)

Risk Factors & Monitoring

Higher risk of side effects in patients with liver disease
Increased sensitivity to sunlight (sun protection is strongly recommended)
May require dose adjustment in long-term therapy
Regular liver function tests are usually recommended during treatment
Periodic monitoring of overall health status is important for safe long-term use

FAQs

What is Pirfeheal Tablet (Pirfenidone) used for?
Pirfeheal Tablet containing Pirfenidone is mainly used to treat idiopathic pulmonary fibrosis (IPF), a long-term lung disease that causes scarring of lung tissue and makes breathing difficult. It helps slow down disease progression.

How does Pirfeheal Tablet work in the body?
It works by reducing the activity of substances in the body that cause inflammation and fibrosis (scarring). This helps slow the buildup of scar tissue in the lungs and preserves lung function for a longer time.

Can Pirfeheal Tablet be taken by children?
No, Pirfenidone is generally not recommended for children. It is mainly prescribed for adults with pulmonary fibrosis under strict medical supervision.

How should I take Pirfeheal Tablet?
It should be taken exactly as prescribed by your doctor, usually with food to reduce stomach side effects like nausea. The dose is gradually increased depending on tolerance and treatment plan.

Interactions

General Interaction Overview

Pirfeheal Tablet (Pirfenidone) may interact with certain medicines that affect its metabolism or increase the risk of side effects, especially liver-related toxicity. These interactions can change how the drug works in the body, so it is important to inform your healthcare provider about all medicines you are using before starting treatment.

Commonly Reported Interactions

✔ CYP1A2 inhibitors (e.g., fluvoxamine)
Can significantly increase pirfenidone levels in the blood, raising the risk of side effects and toxicity.

✔ Ciprofloxacin (especially high-dose use)
May increase pirfenidone concentration, requiring dose adjustment or close monitoring.

Important Note

Always inform your doctor about all prescription medicines, over-the-counter drugs, and supplements you are taking. This helps prevent unwanted interactions and ensures safe and effective treatment with Pirfeheal Tablet.