Loparin (Enoxaparin Injection): Anticoagulant Injection | For Blood Clots, DVT, PE Prevention and Treatment

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Loparin Injection contains Enoxaparin, a low-molecular-weight heparin (LMWH) anticoagulant used to prevent and treat harmful blood clots. It is commonly used for conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and certain heart-related clotting conditions. Enoxaparin reduces clot formation by enhancing the activity of antithrombin and primarily inhibiting Factor Xa.

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Loparin 20 Mg/0.2ml Injection (Enoxaparin 20mg/0.2ml)
PackageQTYPriceAdd To Cart
1 Injection $5.12
3 Injection/s $15.36
6 Injection/s $30.72

Loparin 40 Mg/0.4ml Injection (Enoxaparin 40mg/0.4ml)
PackageQTYPriceAdd To Cart
1 Injection $7.13
3 Injection/s $21.39
6 Injection/s $42.78

Loparin 60 Mg/0.6ml Injection (Enoxaparin 60mg/0.6ml)
PackageQTYPriceAdd To Cart
1 Injection $8.37
3 Injection/s $25.11
6 Injection/s $50.22

Product Overview

What Is Loparin Injection?

Loparin Injection contains Enoxaparin, a low-molecular-weight heparin (LMWH) anticoagulant used to prevent and treat certain blood clots. It is commonly used to reduce the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE) in appropriate patients and may also be used in certain heart-related conditions.

How Does Loparin Injection Work?

Enoxaparin enhances the activity of antithrombin and primarily inhibits Factor Xa, an important protein involved in the blood-clotting process. This anticoagulant action helps reduce the formation and growth of harmful blood clots.

Product Information
 
Details
Product NameLoparin Injection
Active IngredientEnoxaparin Sodium
Product TypeAnticoagulant
Dosage FormInjection
Main UsesPrevention and treatment of certain blood clots
RouteUsually subcutaneous injection

 

What Is Loparin Injection Used For?

Loparin Injection is used to help prevent and treat certain blood-clotting conditions. It may be used after certain surgical procedures, in people with an increased risk of venous blood clots, and for the management of selected DVT, PE, and acute coronary conditions.

Blood Clot Prevention

Enoxaparin helps reduce the formation of blood clots in people who have an increased risk of venous thromboembolism. It may be used during periods of limited mobility or following certain surgical procedures.

Deep Vein Thrombosis

Loparin may be used to prevent or treat deep vein thrombosis (DVT), a condition in which a blood clot forms in a deep vein, commonly in the legs.

Pulmonary Embolism

Enoxaparin may be used in appropriate cases to help prevent or treat pulmonary embolism (PE), which can occur when a blood clot travels to the lungs.

Heart-Related Conditions

Loparin may also be used as part of treatment for certain acute coronary conditions, including unstable angina and specific types of myocardial infarction, according to the healthcare professional's instructions.

Anticoagulant Action

The active ingredient, Enoxaparin Sodium, reduces clotting activity primarily through Factor Xa inhibition. This helps limit the formation and progression of harmful blood clots.

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Precautions

Loparin (Enoxaparin Injection) should be used carefully because it reduces blood clotting and can increase the risk of bleeding. Appropriate precautions are particularly important in people with kidney impairment, bleeding disorders, low body weight, or those undergoing spinal or epidural procedures.

Key Precautions

  • Use Loparin only under the direction of a qualified healthcare professional.

  • Inform your doctor if you have kidney disease, as severe renal impairment may require dose adjustment.

  • Tell your doctor if you have a history of unusual bleeding, bleeding disorders, low platelet counts, or heparin-induced thrombocytopenia (HIT).

  • Inform your healthcare team before any spinal or epidural anesthesia, lumbar puncture, or other spinal procedure because of the risk of spinal or epidural bleeding.

  • Inform your doctor about all medicines you take, especially aspirin, NSAIDs, antiplatelet medicines, or other anticoagulants, as they may increase bleeding risk.

  • Use with particular caution in older adults and people with low body weight because bleeding risk may be increased.

  • Do not change the dose or stop treatment without medical guidance.

When to Consult a Doctor

  • Unusual, prolonged, or heavy bleeding

  • Large or unexplained bruising

  • Blood in the urine or stool

  • Severe or persistent headache

  • Sudden weakness, numbness, or difficulty moving the legs

  • Back pain or loss of bladder or bowel control after a spinal or epidural procedure

  • Signs of an allergic reaction such as swelling, rash, or difficulty breathing

These symptoms may require prompt medical evaluation, particularly because serious bleeding and spinal hematoma are recognized risks with enoxaparin.

Usage

Loparin (Enoxaparin Injection) is generally administered by subcutaneous injection to prevent or treat certain blood clots. It should be used exactly according to the healthcare professional's instructions for safe and effective anticoagulant treatment.

Uses

  • Prevention of deep vein thrombosis (DVT)
  • Treatment of certain DVT and pulmonary embolism (PE) cases
  • Prevention of blood clots after certain surgical procedures
  • Prevention of clot-related complications in patients at increased risk
  • Management of certain acute coronary conditions, as directed by a healthcare professional

Dosage and Administration

ParameterDetails
FormInjectable solution
DoseIndividualized according to the condition and patient factors
RouteUsually subcutaneous injection
FrequencyAs directed by the healthcare professional
PrescriptionRequired

How to Use

  • Loparin should be administered exactly as instructed by your healthcare professional.
  • If self-injection is recommended, receive proper training on the injection technique before administering it yourself.
  • Use the prescribed dose and injection schedule consistently.
  • Do not change the dose or stop treatment without medical advice.
  • Do not inject Loparin into a muscle unless specifically instructed.
  • Dispose of used syringes safely in an appropriate sharps container.
  • Keep the injection stored according to the product instructions.

Missed Dose

  • If you miss a scheduled dose, follow your healthcare professional's instructions.
  • Do not administer an extra dose to compensate for a missed injection unless specifically advised.
  • Contact your healthcare professional if you are unsure about the appropriate next dose.

Side Effects

Loparin (Enoxaparin Injection) is generally tolerated when used appropriately, but some side effects may occur. Since Enoxaparin reduces blood clotting, bleeding and bruising are among the most important effects to monitor.

Common Side Effects

  • Bleeding or increased bruising

  • Pain, redness, or irritation at the injection site

  • Anemia

  • Headache

  • Nausea

  • Diarrhea

  • Mild swelling at the injection site

When to Seek Medical Advice

  • Heavy, unusual, or prolonged bleeding

  • Blood in the urine or stool

  • Vomiting blood or coughing up blood

  • Severe or persistent headache

  • Large or unexplained bruises

  • Signs of an allergic reaction, such as rash, facial swelling, or difficulty breathing

  • Sudden weakness, numbness, or other unusual neurological symptoms

  • Back pain or leg weakness following a spinal or epidural procedure

If any severe or unusual symptoms occur during treatment, seek prompt medical attention. Do not stop Loparin on your own unless instructed by a healthcare professional.

FAQs

What is Loparin Injection used for?

Loparin Injection contains Enoxaparin and is used to prevent and treat certain blood clots, including deep vein thrombosis (DVT) and pulmonary embolism (PE). It may also be used in certain heart-related conditions.

How does Enoxaparin work?

Enoxaparin is an anticoagulant that enhances the activity of antithrombin and primarily inhibits Factor Xa. This reduces the body's ability to form and extend harmful blood clots.

How is Loparin Injection administered?

Loparin is commonly administered as a subcutaneous injection under the skin. The dose and frequency depend on the condition being treated and individual factors such as kidney function and body weight.

Can Loparin cause bleeding?

Yes. Since Enoxaparin reduces blood clotting, bleeding and easy bruising can occur. Unusual, prolonged, or heavy bleeding should be reported to a healthcare professional promptly.

Can I stop Loparin if I feel better?

Do not stop Loparin on your own. The duration of treatment depends on the reason for use and your individual clotting risk. Follow your healthcare professional's instructions carefully.

Can Loparin be taken with aspirin or ibuprofen?

These medicines can increase the risk of bleeding when used with Enoxaparin. Inform your healthcare professional before taking aspirin, ibuprofen, naproxen, or other medicines that affect blood clotting.

What should I do if I miss a dose?

Follow the missed-dose instructions provided by your healthcare professional. Do not administer an extra dose to compensate for a missed injection unless specifically advised.

Is Loparin suitable for everyone?

No. Its suitability depends on factors such as bleeding risk, kidney function, platelet levels, medical history, and other medicines being used. A healthcare professional should determine whether it is appropriate.

Interactions

Loparin (Enoxaparin Injection) may interact with medicines that affect blood clotting or platelet function. Using these medicines together can increase the risk of bleeding and should be done only with appropriate healthcare guidance.

Possible Interactions

  • Aspirin and antiplatelet medicines may increase the risk of bleeding.
  • NSAIDs such as ibuprofen and naproxen may increase bleeding risk.
  • Other anticoagulants, including warfarin or heparin, may enhance the anticoagulant effect.
  • Thrombolytic medicines used to dissolve blood clots may increase the likelihood of bleeding.
  • Certain medicines that affect platelet function or blood clotting may require additional monitoring.

Important Advice

  • Inform your doctor about all medicines, vitamins, and herbal supplements you are taking.
  • Do not start aspirin, ibuprofen, naproxen, or another medicine that affects blood clotting without medical advice.
  • Avoid self-medication while using Loparin.
  • Follow the recommended dose and treatment schedule carefully.
  • Report unusual bruising, prolonged bleeding, blood in urine or stool, or other signs of bleeding promptly.
More Information Demo
Manufacturer:Sanofi India Ltd (maker of Clexane),
Equivalent Brand:Lovenox
Generic Search:Enoxaparin Injection