Lupride 1mg Injection (Leuprolide + Leuprorelin)
Lupride 1mg Injection is a prescription medication used to treat hormone-responsive conditions such as prostate cancer, endometriosis, uterine fibroids, and central precocious puberty. It contains Leuprolide Acetate (also known as Leuprorelin), a synthetic gonadotropin-releasing hormone (GnRH) agonist. This injection works by reducing the levels of certain hormones in the body, thereby slowing or stopping the growth of hormone-sensitive tissues.
Precautions Lupride Injection:
- Pregnancy and Breastfeeding: Not recommended during pregnancy or while breastfeeding due to potential harm to the fetus or infant.
- Bone Health: May cause bone thinning; calcium and vitamin D supplements might be advised.
- Diabetes: Can elevate blood sugar levels; diabetic patients should monitor glucose levels closely.
- Cardiovascular Health: Potential risk of QT prolongation; inform your doctor if you have heart conditions.
- Seizure Disorders: Use with caution in individuals with a history of seizures.​
Uses of Lupride Injection:
- Prostate Cancer: Helps in reducing testosterone levels to slow the growth of prostate tumors.
- Endometriosis: Alleviates pain and reduces endometrial lesions by lowering estrogen levels.
- Uterine Fibroids: Shrinks fibroids and controls heavy menstrual bleeding.
- Central Precocious Puberty: Delays early onset puberty in children by regulating hormone levels.
Side Effect of Lupride Injetion:
| Side Effect | Severity |
| Hot flashes | Common |
| Decreased libido | Common |
| Fatigue | Common |
| Muscle weakness | Common |
| Increased sweating | Common |
| Bone density loss | Moderate |
| Menstrual irregularities | Moderate |
| Elevated blood sugar levels | Moderate |
| Mood changes (e.g., depression) | Moderate |
| QT prolongation (heart rhythm issues) | Rare |
FAQs of Lupride Injection:
1. Is Lupride 1mg Injection a chemotherapy drug?
No, it's a hormonal therapy that reduces hormone levels to treat hormone-sensitive conditions.​
2. Can Lupride 1mg Injection affect menstrual cycles?
Yes, it may cause periods to stop temporarily. Inform your doctor if bleeding continues.​
3. Does Lupride 1mg Injection impact bone health?
Long-term use can decrease bone density. Regular monitoring and supplements may be necessary.​
4. Can Lupride 1mg Injection cause blood sugar changes?
Yes, it may increase blood sugar levels; diabetic patients should monitor levels closely.
Interactions of Lupride Injection:
Inform your healthcare provider about all medications and supplements you are taking. Lupride 1mg Injection may interact with:​
- Hormonal Therapies: Estrogens, progestins, testosterone.
- QT-Prolonging Drugs: Certain antiarrhythmics, antipsychotics.
- Herbal Supplements: Black cohosh, DHEA, chasteberry.
- Other Medications: Cisapride, dronedarone, pimozide, thioridazine.​
| Manufacturer | : | Sun Pharmaceutical Industries Ltd |
| Equivalent Brand | : | Lupron |
| Generic Search | : | Leuprolide (Leuprorelin) |
