Pirfenex Tablet (Pirfenidone)

Pirfenidone, marketed under the brand names Pirfenex and Esbriet, is a medication that has gained significant recognition for its role in the management of pulmonary fibrosis.

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Pirfenex 200 Tablet (Pirfenidone 200mg)

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90 Tablet/s $60.00
180 Tablet/s $115.00
270 Tablet/s $160.00

Pirfenex 600 Tablet (Pirfenidone 600mg)

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90 Tablet/s $115.00
180 Tablet/s $225.00
270 Tablet/s $310.00

Pirfenex 400 Tablet (Pirfenidone 400mg)

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90 Tablet/s $95.00
180 Tablet/s $185.00
270 Tablet/s $270.00

Introduction to Pirfenex Tablet (Pirfenidone)

Pirfenidone, marketed under the brand names Pirfenex and Esbriet, is a medication that has gained significant recognition for its role in the management of pulmonary fibrosis. In this comprehensive guide, we will delve into various aspects of Pirfenidone Tablets, including dosage information, precautions, drug interactions, uses, side effects, and more. Additionally, we will explore the availability of Pirfenex Tablets online and its generic alternatives.

Pirfenidone Dosage and Administration

Pirfenidone is available in tablet form, primarily in two strengths: 200mg and 267mg. The appropriate dosage of Pirfenidone may vary based on individual patient factors and the specific brand of medication prescribed (Pirfenex or Esbriet). It is crucial to follow your healthcare provider's instructions regarding dosage, as they will tailor the treatment to your specific condition and needs.

For Pirfenex Tablets, the recommended starting dosage typically involves taking three tablets (200mg each) three times daily, which amounts to a total daily dose of 1,800mg. This dose may be adjusted based on your response to treatment and any side effects you experience. It is essential to take Pirfenex with food to enhance its absorption and reduce the likelihood of stomach upset.

Esbriet, the other brand of Pirfenidone, is typically prescribed at a lower dosage. Patients are often advised to take three tablets (267mg each) three times daily, totaling 801mg per dose and 2,403mg per day. Like Pirfenex, Esbriet should also be taken with food to optimize its effectiveness and minimize gastrointestinal discomfort.

What to Do in Case of a Missed Dose or Overdose

Missing a dose of Pirfenidone can impact the effectiveness of your treatment. If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed one and resume your regular dosing schedule. Never double up on doses to compensate for a missed dose.

In the event of an overdose, seek immediate medical attention or contact a poison control center. Overdosing on Pirfenidone can lead to severe side effects and complications. Symptoms of an overdose may include dizziness, confusion, nausea, vomiting, and abdominal pain. It is essential to store Pirfenidone tablets in a secure place to prevent accidental ingestion by children or pets.

Pirfenex Tablets Online:

Availability of Pirfenex Tablets Online

For the convenience of patients and caregivers, Pirfenex Tablets are available for purchase online at our website, 1mgstore.com. Ordering medication online can provide a hassle-free way to access Pirfenex, and it may be particularly beneficial for those who have difficulty obtaining it through traditional means. When purchasing Pirfenex online, it is crucial to ensure that you are sourcing the medication from a reputable and licensed pharmacy to guarantee product quality and authenticity.

Exploring Pirfenidone 200mg Tablets

Pirfenidone is commonly available in the 200mg tablet form, which is the standard dosage strength for Pirfenex Tablets. This dosage is widely prescribed for the management of pulmonary fibrosis and is usually taken three times daily with food. Patients should follow their healthcare provider's guidance regarding the appropriate Pirfenidone dosage for their specific condition.

Pulmonary Fibrosis Medication

Pirfenidone's Role in Pulmonary Fibrosis Treatment

Pulmonary fibrosis is a debilitating lung condition characterized by the progressive scarring of lung tissue, leading to breathing difficulties and reduced lung function. Pirfenidone, available as Pirfenex and Esbriet, is a vital medication in the management of this condition. Here are key points to consider:

  • Disease Management: Pirfenidone does not cure pulmonary fibrosis but can help slow down its progression, reduce inflammation, and improve lung function.
  • Early Intervention: Starting Pirfenidone early in the course of the disease may have a more significant impact on slowing disease progression.
  • Individualized Treatment: The dosage and treatment plan may vary from person to person, depending on the severity of the disease and individual response to the medication.
  • Monitoring: Regular check-ups and monitoring of lung function and side effects are essential during Pirfenidone treatment.
  • Lifestyle Considerations: In addition to medication, pulmonary fibrosis patients may benefit from pulmonary rehabilitation, oxygen therapy, and lifestyle modifications to manage their condition effectively.
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Before starting Pirfenidone treatment/Esbriet, it is vital to discuss your medical history and any underlying conditions with your healthcare provider.

  • Allergies: Inform your healthcare provider of any allergies you have, especially if you are allergic to Pirfenidone or any of its components.
  • Liver Problems: Pirfenidone can affect liver function, so regular liver function tests are necessary during treatment. If you have liver disease, your healthcare provider may need to adjust your dosage or monitor you closely.
  • Pregnancy and Breastfeeding: Pirfenidone may harm an unborn baby, so it should not be used during pregnancy. Additionally, it is not recommended for breastfeeding mothers, as it may pass into breast milk.
  • Kidney Issues: Patients with severe kidney impairment may require dosage adjustments, so inform your healthcare provider if you have kidney problems.
  • Side Effects: Be vigilant about monitoring and reporting any unusual or severe side effects to your healthcare provider.

Medical Applications of Pirfenidone Tablets/Esbriet 

Pirfenidone is primarily prescribed for the treatment of pulmonary fibrosis, a chronic and progressive lung disease characterized by scarring of lung tissue. The medication works by reducing inflammation and fibrosis in the lungs, potentially slowing down disease progression and improving lung function. It is important to note that Pirfenidone is not a cure for pulmonary fibrosis but can help manage its symptoms and slow its progression.

Generic Pirfenidone for Sale:

In addition to brand-name Pirfenex and Esbriet, generic versions of Pirfenidone are also available. These generics offer an affordable alternative to the brand-name medications while providing the same active ingredient and therapeutic effects. At our website, 1mgstore.com, you can find generic Pirfenidone for sale. It is essential to consult with your healthcare provider to determine whether generic Pirfenidone is a suitable option for your treatment plan.

Common and Rare Side Effects of Pirfenidone/Esbriet 

Like all medications, Pirfenidone can cause side effects, ranging from common and mild to rare and severe. It is essential to be aware of potential side effects and report any unusual symptoms to your healthcare provider. Common side effects may include:

  • Nausea and Vomiting
  • Diarrhea
  • Fatigue
  • Rash
  • Loss of Appetite

Rare but more severe side effects may include:

  • Liver Problems: Symptoms may include yellowing of the skin or eyes, dark urine, and abdominal pain.
  • Gastrointestinal Issues: Severe gastrointestinal side effects like severe diarrhea may occur.
  • Hypersensitivity Reactions: Allergic reactions, though rare, can manifest as skin rash, itching, and difficulty breathing.
  • Elevated Blood Pressure: Pirfenidone can cause an increase in blood pressure, which should be monitored during treatment.

It is important to note that not everyone will experience these side effects, and some individuals may tolerate Pirfenidone well without significant issues. Your healthcare provider will monitor your condition and adjust treatment as needed to manage any side effects.

Frequently Asked Queries About Pirfenex Tablet (Pirfenidone)

QI. Is Pirfenidone/Esbriet a Cure for Pulmonary Fibrosis?

No, Pirfenidone is not a cure for pulmonary fibrosis. It is a medication that helps slow down the progression of the disease and manage its symptoms.

QII. Can I Purchase Pirfenex Online Without a Prescription?

No, you cannot purchase Pirfenex online without a prescription. Pirfenidone is a prescription medication, and it is essential to consult with a healthcare provider before starting treatment.

QIII. What Should I Do If I Miss a Dose of Pirfenidone?

If you miss a dose, take it as soon as you remember. However, if it's close to the next scheduled dose, skip the missed one. Do not double up on doses.

QIV. Are There Any Dietary Restrictions While Taking Pirfenidone?

There are no specific dietary restrictions, but taking Pirfenidone with food can help reduce stomach upset and improve absorption.

QV. Can Pirfenidone Be Used During Pregnancy?

No, Pirfenidone should not be used during pregnancy as it may harm the unborn baby. Consult your healthcare provider for alternative treatment options.

QVI. Are There Alternative Medications for Pulmonary Fibrosis?

Yes, aside from Pirfenidone, another medication called Nintedanib is also used to treat pulmonary fibrosis. Your healthcare provider can determine which is more suitable for you.

QVII. How Long Does Pirfenidone Treatment Typically Last?

The duration of Pirfenidone treatment varies from person to person. It may be long-term, and your healthcare provider will monitor your condition and adjust treatment as needed.

Some notable drug interactions with Pirfenex Tablet (Pirfenidone) include:

Pirfenidone can interact with other medications, potentially affecting its effectiveness or causing adverse reactions. Inform your healthcare provider about all the drugs, supplements, and herbal products you are taking.

  • CYP1A2 Inhibitors: Medications that inhibit CYP1A2 enzymes, such as fluvoxamine, may increase Pirfenidone levels in the blood, leading to an increased risk of side effects.
  • CYP1A2 Inducers: Drugs that induce CYP1A2 enzymes, like smoking, may decrease Pirfenidone levels, potentially reducing its efficacy.
  • Anticoagulants: Pirfenidone/Esbriet may interact with anticoagulants like warfarin, increasing the risk of bleeding. Close monitoring of blood clotting parameters is essential if you are on both medications.
  • Other Pulmonary Fibrosis Medications: Combining Pirfenidone with other medications used to treat pulmonary fibrosis, such as nintedanib, should be done with caution, as the combined effects are not well studied.
  • Herbal Supplements: Some herbal supplements, particularly those affecting liver function, may interact with Pirfenidone. Consult your healthcare provider before taking any herbal products.
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Manufacturer:Cipla Pharma, India
Equivalent Brand:Esbriet
Generic Search:Pirfenidone