Rabiace DSR Capsule (Rabeprazole + Domperidone) | Used for Acid Reflux, GERD & Digestive Symptoms

Precaution

1. Use Only as Prescribed

Take Rabiace DSR only according to the instructions provided by your doctor or pharmacist.

2. Check the Exact Strength

Different Rabeprazole-Domperidone products can have different strengths and release formulations. Check the pack before taking the medicine.

3. Heart Conditions

Tell your doctor if you have a history of heart disease, abnormal heart rhythm, slow heart rate, heart failure, or other cardiac problems. Domperidone has been associated with serious heart-rhythm risks.

4. QT Interval Problems

Domperidone should not be used in patients with certain abnormalities of cardiac electrical activity, including prolonged QT interval.

5. Electrolyte Imbalance

Tell your doctor if you have low potassium, low magnesium, or other significant electrolyte abnormalities because these can increase cardiac risk with Domperidone.

6. Liver Problems

Inform your doctor about liver disease. Domperidone is contraindicated in moderate or severe hepatic impairment under EMA guidance.

7. Kidney Problems

Patients with impaired kidney function may require adjustment of treatment, particularly if Domperidone is used for an extended period.

Usage 

Take Rabiace DSR Capsule exactly as prescribed. Follow the instructions on the product label regarding timing in relation to food and swallowing the capsule. Do not crush, chew, or open a modified-release formulation unless the product instructions specifically allow it.

The duration of treatment depends on the condition being treated and the medical assessment. Domperidone-containing treatment should not be continued unnecessarily or for longer than recommended.

Uses

1. Acid Reflux

The Rabeprazole component reduces stomach acid and can help manage acid-related reflux symptoms.

2. Gastroesophageal Reflux Disease (GERD)

Rabeprazole is used in the treatment of GERD and related acid-mediated conditions.

3. Heartburn Associated With Acid Reflux

By reducing gastric acid production, Rabeprazole can help relieve acid-related heartburn.

4. Nausea and Vomiting

Domperidone is used for the relief of nausea and vomiting in jurisdictions where this is an approved indication.

5. Acid-Related Upper Digestive Symptoms

The combination may be prescribed in some markets when acid suppression and management of associated gastrointestinal symptoms are considered appropriate.

Side Effects

Common Side Effects

Some people may experience:

• Headache
• Nausea
• Abdominal discomfort or pain
• Diarrhea
• Constipation
• Gas or flatulence
• Dizziness

Serious Side Effects

Seek medical attention if you experience:

• Fast, irregular, or unusual heartbeat
• Palpitations
• Fainting or loss of consciousness
• Severe dizziness
• Difficulty breathing
• Signs of a serious allergic reaction
• Persistent or severe diarrhea

FAQs

1. What is Rabiace DSR Capsule used for?

Rabiace DSR contains Rabeprazole and Domperidone. It is used in some markets for acid-related digestive symptoms, while Domperidone is specifically approved in some jurisdictions for short-term relief of nausea and vomiting.

2. What does Rabeprazole do in Rabiace DSR?

Rabeprazole is a proton pump inhibitor that reduces stomach acid production and is used for conditions such as GERD.

3. What does Domperidone do?

Domperidone affects gastrointestinal motility and has antiemetic activity. It can help relieve nausea and vomiting in approved uses.

4. Can Rabiace DSR help with acid reflux?

The Rabeprazole component reduces stomach acid and can help manage acid reflux and GERD.

5. Can Rabiace DSR be used for nausea?

Domperidone is used for nausea and vomiting in jurisdictions where this indication is approved. Its use should follow the applicable local prescribing information.

6. Can I take Rabiace DSR for a long time?

Do not use it for longer than prescribed. In particular, Domperidone is subject to short-duration restrictions in some jurisdictions because of its cardiac safety profile.

7. Who should be cautious with Rabiace DSR?

People with certain heart conditions, abnormal heart rhythms, significant electrolyte disturbances, moderate or severe liver impairment, or those taking interacting medicines may need to avoid Domperidone or use it only under specific medical guidance.

Interactions

1. QT-Prolonging Medicines

Domperidone should not be combined with certain medicines that prolong the QT interval because of the potential for serious cardiac rhythm problems.

2. Potent CYP3A4 Inhibitors

Some medicines can reduce the breakdown of Domperidone and increase its concentration. Potent CYP3A4 inhibitors are contraindicated under EMA guidance.

3. Certain Anti-Infective Medicines

Some antifungal and antibacterial medicines can interact with Domperidone, particularly when they affect cardiac rhythm or CYP3A4 metabolism.

4. Medicines Affecting Electrolytes

Medicines that contribute to low potassium or magnesium may increase the risk of cardiac rhythm problems when combined with Domperidone.

5. Anticoagulants and Other Regular Medicines

Tell your doctor about all regular medicines before starting treatment so potential interactions can be assessed.

6. Acid-Reducing Medicines

Avoid adding other acid-suppressing medicines without professional advice. Combining treatments unnecessarily may change the intended treatment plan.

7. Herbal Products and Supplements

Tell your healthcare professional about herbal products and supplements because their effects and interactions may not always be predictable.