Vomistop Tablet (Domperidone) | Used for Nausea, Vomiting & Digestive Symptoms
Vomistop Tablet contains Domperidone, a medicine that helps control nausea and vomiting. It works mainly by blocking dopamine receptors and can also increase movement through the upper digestive tract.
Product Overview
Vomistop Tablet contains Domperidone, a dopamine receptor antagonist used to manage certain symptoms of nausea and vomiting. Domperidone acts mainly on dopamine receptors outside the brain and also has effects on the movement of the upper gastrointestinal tract.
By increasing gastric and upper intestinal motility and supporting movement of stomach contents, Domperidone may help with symptoms associated with delayed gastric emptying and nausea. The exact approved uses and duration of treatment can vary according to the country, product formulation, and medical condition.
Domperidone should be used at the lowest effective dose for the shortest appropriate duration, because it has been associated with changes in the heart's electrical activity and an increased risk of serious cardiac rhythm problems in some patients.
Before using Vomistop Tablet, inform your doctor about any history of heart disease, abnormal heart rhythm, electrolyte problems, liver disease, or previous reactions to Domperidone. Your doctor should also know about all medicines and supplements you are taking because several medicines can interact with Domperidone.
Product Information
| Product Name | Vomistop Tablet |
| Active Ingredient | Domperidone |
| Medicine Type | Antiemetic / Gastrointestinal Motility Medicine |
| Drug Class | Dopamine D2-Receptor Antagonist |
| Dosage Form | Tablet |
| Route | Oral |
| Main Uses | Nausea and vomiting; certain gastrointestinal motility symptoms |
| Main Action | Helps reduce nausea and supports upper gastrointestinal motility |
| Administration | As directed by a healthcare professional |
| Important Precaution | Cardiac rhythm-related risks and medicine interactions |
How Domperidone Works
Domperidone blocks dopamine D2 receptors that are involved in the vomiting response. This reduces signals that can contribute to nausea and vomiting. It also increases movement in the upper gastrointestinal tract, which can support the passage of stomach contents.
Important Information
Vomistop Tablet should be taken only as recommended by a healthcare professional. Because Domperidone can interact with several medicines and may affect cardiac rhythm, medical advice is particularly important for people with heart conditions or those taking multiple medicines.
Precaution
- Use Vomistop Tablet only according to medical advice.
- Tell your doctor if you have a history of heart disease, irregular heartbeat, prolonged QT interval, or other heart rhythm problems.
- Inform your doctor if you have significant liver disease.
- Tell your doctor if you have low potassium, low magnesium, or other electrolyte abnormalities.
- Do not use Domperidone with certain medicines that can prolong the QT interval or strongly inhibit its metabolism.
- Inform your doctor about all prescription medicines, over-the-counter medicines, vitamins, and supplements you take.
- Older adults may have a higher risk of serious cardiac adverse effects.
- Seek medical attention if you develop a fast or irregular heartbeat, fainting, severe dizziness, or other symptoms suggesting an abnormal heart rhythm.
- Do not exceed the recommended dose.
- Do not continue treatment longer than advised.
- If symptoms persist or become worse, consult a healthcare professional.
- Pregnant or breastfeeding individuals should discuss Domperidone use with a healthcare professional before treatment.
- Keep the medicine out of reach of children.
- Store the tablets according to the instructions on the product packaging.
Usage
- Take Vomistop Tablet exactly as directed by your doctor or pharmacist.
- The tablet should be taken orally with water.
- Follow the prescribed timing and treatment duration.
- Do not take more tablets than recommended.
- Do not extend treatment without medical advice.
- If you forget a dose, take it when remembered unless it is nearly time for the next dose. Do not take two doses together.
- Tell your healthcare professional if symptoms do not improve or return after treatment.
- Inform your doctor about other medicines before starting Domperidone.
- Avoid self-treatment with Domperidone, particularly if you have heart or liver problems.
Uses
1. Nausea and Vomiting
Domperidone may be prescribed to relieve certain symptoms of nausea and vomiting.
2. Gastrointestinal Motility Symptoms
Because Domperidone can increase upper gastrointestinal motility, it may be used in selected gastrointestinal conditions where impaired movement contributes to symptoms.
3. Delayed Gastric Emptying
In some clinical settings, Domperidone may be prescribed for symptoms associated with delayed gastric emptying, depending on local prescribing guidance and the patient's condition.
Side Effects
Like other medicines, Vomistop Tablet may cause side effects.
Common or Possible Side Effects
- Dry mouth
- Headache
- Dizziness
- Abdominal discomfort
- Diarrhea
- Increased thirst
Domperidone can also increase prolactin levels, which may cause breast tenderness, breast enlargement, milk production, or menstrual changes in some people.
Serious Side Effects
Although uncommon, Domperidone has been associated with serious heart rhythm problems.
Seek urgent medical attention if you experience:
- Fast or irregular heartbeat
- Fainting
- Severe dizziness
- Seizure
- Difficulty breathing or signs of a serious allergic reaction
The risk of serious cardiac effects may be higher in people with certain heart conditions, electrolyte abnormalities, liver impairment, or when Domperidone is combined with interacting medicines.
FAQs
1. What is Vomistop Tablet?
Vomistop Tablet contains Domperidone, a dopamine D2-receptor antagonist used for certain symptoms of nausea and vomiting and, in selected situations, gastrointestinal motility problems.
2. What is Vomistop Tablet used for?
It may be prescribed to manage certain nausea and vomiting symptoms and selected gastrointestinal motility-related symptoms.
3. How does Domperidone work?
Domperidone blocks dopamine D2 receptors and also increases movement in the upper gastrointestinal tract, helping reduce nausea and support the movement of stomach contents.
4. Is Vomistop Tablet used for vomiting?
Yes. Domperidone can be prescribed for certain types of nausea and vomiting.
5. How should Vomistop Tablet be taken?
Take it orally according to the dose and schedule prescribed by your healthcare professional. Do not exceed the recommended amount.
6. Can Domperidone cause sleepiness?
Drowsiness or dizziness can occur in some people, although these effects are not experienced by everyone. Avoid activities requiring alertness if you feel affected.
7. What are the common side effects of Domperidone?
Possible side effects include dry mouth, headache, dizziness, abdominal discomfort, and changes related to increased prolactin levels.
8. Can Domperidone affect the heart?
Yes. Domperidone has been associated with QT prolongation and serious abnormal heart rhythms, particularly in people with certain risk factors or when used with interacting medicines.
Interactions
Domperidone can interact with other medicines, and some combinations should be avoided.
Medicines That Affect Heart Rhythm
Medicines that prolong the QT interval may increase the risk of abnormal heart rhythms when combined with Domperidone. Your doctor should review your medicines before treatment.
Strong CYP3A4 Inhibitors
Certain medicines that strongly inhibit CYP3A4 can increase Domperidone exposure and may increase cardiac risk. Examples include some azole antifungals and macrolide antibiotics.
Certain Antibiotics and Antifungals
Some antibiotics and antifungal medicines can interact with Domperidone. Do not start these medicines together without medical advice.
Medicines Affecting Stomach Acidity
Some acid-reducing medicines or antacid products may affect how oral Domperidone is absorbed depending on how they are taken. Follow the timing instructions provided by your healthcare professional.
| Manufacturer | : | Vasudha Pharma Chem Limited |
| Equivalent Brand | : | Motilium |
| Generic Search | : | Domperidone |





















