Trajenta Tablet (Linagliptin) | Used to Manage Type 2 Diabetes & Control Blood Sugar

Precaution

Use Trajenta Tablet only as directed by a healthcare professional.

• Inform your doctor if you have previously experienced pancreatitis. The risk in people with a history of pancreatitis has not been established.
• Seek medical attention if you develop persistent or severe abdominal pain, particularly if it spreads toward the back, as this can be a sign of pancreatitis.
• The risk of low blood sugar (hypoglycemia) may increase when Linagliptin is taken together with insulin or insulin-releasing medicines such as sulfonylureas.
• Tell your doctor if you have a history or risk factors for heart failure and report symptoms such as unusual shortness of breath or swelling.
• Stop the medicine and seek medical attention if signs of a serious allergic reaction such as facial or throat swelling, difficulty breathing, or severe skin reactions occur.
• Contact your doctor if you develop severe or persistent joint pain.
• Report new blisters or skin erosions because rare cases of bullous pemphigoid have been reported.
• Inform your doctor about all medicines, supplements, and herbal products you take.
• Trajenta should not be used by people with a known hypersensitivity to Linagliptin or any of its ingredients.

Usage 

Take Trajenta Tablet exactly as prescribed by your doctor. The usual recommended dose is 5mg once daily, and it can be taken with or without food. Try to take it at approximately the same time each day.

Swallow the tablet with water and do not change the dose or stop treatment without medical advice. Trajenta should be used as part of a complete diabetes-management plan that may include appropriate diet, physical activity, and other prescribed medicines.

If you miss a dose, take it when you remember unless it is almost time for the next dose. Do not take two doses at the same time to make up for a missed dose.

Uses

Trajenta Tablet is used to:

• Manage type 2 diabetes mellitus
• Improve blood glucose control
• Support glycemic control alongside diet and exercise
• Be used alone when certain other diabetes medicines are unsuitable
• Be combined with other diabetes medicines when additional glucose control is needed

It is not recommended for type 1 diabetes, as it is not effective for this condition.

Side Effects

Common Side Effects

Some people taking Linagliptin may experience:

• Nasopharyngitis (cold-like symptoms)
• Cough
• Diarrhea
• Headache
• Increased blood lipase levels

Nasopharyngitis is the most commonly reported adverse reaction in the U.S. prescribing information.

Serious Side Effects

Seek medical attention if you experience:

• Severe or persistent abdominal pain that may indicate pancreatitis
• Symptoms of severe allergic reaction, such as swelling of the face, lips, tongue, or throat
• Difficulty breathing
• Severe skin reactions
• Severe or disabling joint pain
• Blisters or erosions on the skin

FAQs

1. What is Trajenta Tablet used for?
Trajenta Tablet is used to improve blood sugar control in adults with type 2 diabetes, together with diet and exercise.

2. What is the active ingredient in Trajenta?
The active ingredient is Linagliptin, a DPP-4 inhibitor.

3. What is the usual dose of Trajenta?
The recommended dose is generally 5mg once daily, with or without food. Follow your doctor's instructions for your individual treatment.

4. Can Trajenta be taken with food?
Yes. Trajenta can be taken with or without food.

5. Can Trajenta be used with other diabetes medicines?
Yes. Linagliptin may be used with other diabetes medicines, including insulin, when additional blood sugar control is required.

6. Is Trajenta used for type 1 diabetes?
No. Trajenta is not recommended for type 1 diabetes because it is not effective for this condition.

7. Can Trajenta cause low blood sugar?
The risk of hypoglycemia is generally more relevant when Linagliptin is combined with insulin or an insulin secretagogue such as a sulfonylurea.

8. Does Trajenta require a different dose for kidney problems?
The recommended Linagliptin dose is generally 5mg once daily, including in patients with renal impairment. Your doctor should determine whether it is appropriate for you based on your overall health and treatment plan.

Interactions

Trajenta Tablet contains Linagliptin, which may interact with certain medicines and can affect blood sugar control. Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, and herbal supplements you are taking before starting treatment.

1. Insulin: Taking Trajenta with insulin may increase the risk of hypoglycemia (low blood sugar). Your doctor may monitor your blood glucose more closely and adjust the insulin dose if required.
2. Sulfonylureas: Medicines such as glimepiride, glipizide, or other sulfonylureas stimulate insulin release. When used with Linagliptin, the risk of low blood sugar may increase. Your healthcare professional may reduce the dose of the sulfonylurea when necessary.
3. Rifampin: Rifampin is a strong inducer of CYP3A4 and P-glycoprotein (P-gp). It can reduce Linagliptin exposure in the body and may decrease its blood-glucose-lowering effect. If long-term treatment with a strong inducer is required, your doctor may consider an alternative diabetes treatment.
4. Other Strong CYP3A4 or P-gp Inducers: Medicines that strongly increase the activity of CYP3A4 or P-gp may lower the amount of Linagliptin in the body. This may reduce its effectiveness in controlling blood glucose. Inform your doctor if you are taking medicines known to have these effects.
5. Other Antidiabetic Medicines: Trajenta may be prescribed together with other medicines used for type 2 diabetes. Because different diabetes medicines can lower blood glucose through different mechanisms, combined treatment may increase the possibility of hypoglycemia with certain combinations.
6. Medicines That Affect Blood Sugar: Some medicines, including certain corticosteroids, diuretics, and other treatments, may increase or decrease blood glucose levels. These effects can make diabetes harder to control while taking Trajenta. Your doctor may recommend more frequent blood glucose monitoring when such medicines are started or stopped.