Trazonil Tablet (Trazodone)
Trazodone (Trazonil) is a medicine commonly used in neurology for the treatment of depression, anxiety disorders, and insomnia. Desyrel is another brand name for Trazodone.
Product Overview
Trazonil Tablet (Trazodone) is an oral antidepressant formulation containing Trazodone, developed to help manage depressive disorders and associated symptoms such as anxiety, sleep disturbances, and mood imbalance through modulation of neurotransmitter activity in the brain. It is widely used in clinical practice due to its dual benefits in improving mood and supporting healthy sleep patterns.
The formulation works by influencing serotonin activity within the central nervous system, contributing to emotional stabilization and improved sleep quality. Its established therapeutic profile and broad clinical utility make it a commonly prescribed option in psychiatric and supportive mental health care.
Mechanism Insights (How It Works)
- Serotonin Modulation
Trazodone enhances serotonin activity in the brain by inhibiting its reuptake, helping improve mood stability and emotional balance. - Receptor Regulation
The drug also acts on specific serotonin receptors, contributing to reduced anxiety and improved sleep quality. - Central Nervous System Support
By balancing neurotransmitter signaling, Trazodone helps reduce symptoms such as low mood, irritability, restlessness, and insomnia, supporting overall mental well-being.
Administration Guidelines
- Take exactly as prescribed by the physician
- Usually administered after meals to reduce stomach discomfort
- Swallow the tablet whole with water
- Preferably taken at the same time each day
- Avoid abrupt discontinuation without medical guidance
Clinical Considerations
- Commonly prescribed for major depressive disorder and associated insomnia
- Avoid abrupt discontinuation without medical guidance
- Dosage may vary depending on clinical condition and patient response
- Gradual dose adjustment may be recommended for optimal tolerability
- Patients should avoid alcohol and activities requiring alertness until response is known
Precautions:
Usage
General Usage Information
Side Effects
General Safety Information
Trazonil Tablet (Trazodone) is generally well tolerated when used as prescribed. Most side effects are mild and temporary, especially during the initial days of treatment, but their occurrence may vary depending on the individual’s health condition, dosage, and duration of use.
Common Side Effects
✔ Drowsiness or sleepiness
✔ Dizziness or lightheadedness
✔ Dry mouth
✔ Headache
✔ Nausea
✔ Fatigue or weakness
✔ Blurred vision
These effects are usually temporary and may improve as the body adjusts to the medication.
Serious Side Effects (Rare but Important)
âš Seek medical attention if you experience:
- Irregular heartbeat or chest pain
- Severe dizziness or fainting
- Mood changes, worsening depression, or suicidal thoughts
- Painful or prolonged erection (priapism)
- Allergic reactions (rash, itching, swelling, difficulty breathing)
- Seizures or severe confusion
Risk Factors & Monitoring
- Higher risk of side effects in elderly patients and those with heart or liver conditions
- May increase drowsiness when combined with alcohol or sedative medicines
- Dose adjustments may be required in patients with liver or kidney disorders
- Regular medical monitoring may be recommended during long-term use or dose changes
FAQs
Interactions
General Interaction Overview
Trazonil Tablet (Trazodone) may interact with medications that affect brain chemicals, heart rhythm, or liver metabolism. These interactions can increase the risk of side effects such as excessive drowsiness, dizziness, serotonin syndrome, or changes in heart rhythm. It is important to inform your healthcare provider about all medicines, supplements, and herbal products you are using.
Commonly Reported Interactions
- Antidepressants such as SSRIs, SNRIs, or MAO inhibitors may increase the risk of serotonin syndrome
- Sedatives, sleeping pills, alcohol, or anti-anxiety medicines may enhance drowsiness and dizziness
- Certain antibiotics, antifungals, or antiviral medicines may increase trazodone levels in the blood
- Medicines that affect heart rhythm, such as some antipsychotics or antiarrhythmics, may increase the risk of irregular heartbeat
- Blood thinners like warfarin or antiplatelet medicines may increase bleeding risk
- Carbamazepine or phenytoin may reduce the effectiveness of trazodone by increasing its breakdown in the body
Taking trazodone with alcohol should be avoided, as it can worsen drowsiness, impaired coordination, and dizziness.
| Manufacturer | : | Intas Pharma, India |
| Equivalent Brand | : | Desyrel |
| Generic Search | : | Trazodone |













