Veenat Capsule (Imatinib mesylate)
Imatinib mesylate, commonly known by its brand name Veenat, and Gleevec, is a medication used for the treatment of certain types of cancers, including chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs), and other rare blood disorders.
Introduction to Imatinib Mesylate Tablet (Veenat):
Imatinib mesylate, commonly known by its brand name Veenat, and Gleevec is a medication used for the treatment of certain types of cancers, including chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs), and other rare blood disorders. It belongs to a class of medications called tyrosine kinase inhibitors, which work by blocking the activity of specific enzymes that promote the growth of cancer cells.
Imatinib Mesylate Tablet Dosage Information:
- The dosage of Imatinib mesylate tablets (Veenat) varies depending on the type of cancer being treated and the individual patient's condition. It is essential to follow the prescribed dosage instructions provided by your healthcare provider or as mentioned on the product label. Do not modify the dosage or discontinue the medication without consulting your doctor.
- For the treatment of chronic myeloid leukemia (CML), the recommended starting dose of Imatinib mesylate tablet is usually 400 milligrams (mg) per day for adults. The dosage may be adjusted by your doctor based on your response to the treatment. In some cases, the dose may be increased to 600-800 mg per day or reduced to 300 mg per day.
- When used for gastrointestinal stromal tumors (GISTs), the typical dosage of Imatinib mesylate tablet is 400 mg per day for adults. However, the dosage may vary depending on the stage and severity of the cancer.
- For other rare blood disorders, the dosage may differ, and it is crucial to consult with your healthcare provider for the appropriate dosage instructions.
- Imatinib mesylate tablet should be taken orally with a glass of water and can be taken with or without food. It is essential to swallow the tablets whole without crushing, breaking, or chewing them. Follow the prescribed schedule and try to take the medication at the same time each day to maintain a consistent level in your body.
Imatinib mesylate has proven to be a Life-Saving Drug for many individuals diagnosed with these specific types of cancers and rare blood disorders. However, it is important to note that this medication may cause side effects, and its usage should be closely monitored by a healthcare professional.
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Important Safety Advice to be taken while using Veenat Capsule (Imatinib mesylate)
Medical History: Before starting treatment with Imatinib mesylate, inform your healthcare provider about your complete medical history, including any allergies, liver or kidney problems, heart conditions, bleeding disorders, or previous history of pulmonary arterial hypertension (PAH). These factors may influence the suitability and dosage of the medication for your specific case.- Pregnancy and Breastfeeding: Imatinib mesylate/Gleevec has the potential to harm an unborn baby, so it is important to discuss your pregnancy status with your doctor before initiating treatment. Additionally, it is not recommended to breastfeed while taking this medication, as it may pass into breast milk and harm the nursing infant.
- Blood Counts: Imatinib mesylate may affect blood cell counts, leading to a decrease in red blood cells, white blood cells, and platelets. Regular blood tests will be necessary to monitor your blood counts, and any significant changes should be reported to your healthcare provider.
- Liver and Kidney Function: Imatinib mesylate is primarily metabolized in the liver, and its elimination depends on kidney function. Therefore, individuals with impaired liver or kidney function may require adjusted dosages or more frequent monitoring to ensure the medication is being properly processed and to prevent potential complications.
Imatinib mesylate (Veenat) is primarily used for the treatment of the following conditions:
Chronic Myeloid Leukemia (CML): Imatinib mesylate/Gleevec has revolutionized the treatment of CML. It inhibits the abnormal protein produced by the Philadelphia chromosome, effectively controlling the growth of cancer cells. It helps in managing CML in its chronic phase, accelerating or maintaining remission after stem cell transplantation, and treating CML in accelerated or blast crisis phases.
Gastrointestinal Stromal Tumors (GISTs): Imatinib mesylate has shown remarkable effectiveness in treating GISTs, a type of tumor that develops in the gastrointestinal tract. It blocks the activity of certain enzymes, slowing down or halting the growth of cancer cells. Imatinib mesylate can be used as the primary treatment for unresectable or metastatic GISTs or after surgical removal to prevent recurrence.
Other Rare Blood Disorders: Imatinib mesylate has also demonstrated efficacy in the treatment of certain rare blood disorders, including hypereosinophilic syndrome, systemic mastocytosis, and dermatofibrosarcoma protuberans (a rare type of skin cancer). It helps to control the overproduction of abnormal blood cells, preventing complications and improving quality of life.
Imatinib mesylate (Veenat) is an Anti-Cancer medication that has been widely recognized as a life-saving drug in the treatment of chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs), and other rare blood disorders.
Important to notice some adverse effects of Veenat Capsule (Imatinib mesylate)
While Imatinib mesylate is considered a life-saving medication, it may cause certain side effects. It is important to note that not all individuals will experience these side effects, and their severity can vary. Common side effects may include:
Nausea and Vomiting: Imatinib mesylate/Gleevec can cause gastrointestinal disturbances, including nausea and vomiting. Taking the medication with food or dividing the dose throughout the day may help alleviate these symptoms.
Fatigue and Weakness: Some individuals may experience fatigue and weakness while taking Imatinib mesylate. It is important to get enough rest and inform your healthcare provider if these symptoms become persistent or severe.
Edema: Imatinib mesylate may cause fluid retention, leading to swelling in the hands, feet, ankles, or other parts of the body. If you notice significant swelling or discomfort, notify your healthcare provider.
Skin Rash: Skin rash is a possible side effect of Imatinib mesylate. If you develop a rash, inform your doctor, as they may recommend measures to manage the symptoms.
Muscle Cramps: Imatinib mesylate can occasionally cause muscle cramps or muscle pain. Staying hydrated and gentle stretching exercises may help alleviate these symptoms.
Headache: Some individuals may experience headaches while taking Imatinib mesylate. If the headache persists or becomes severe, contact your healthcare provider.
Bleeding and Bruising: Imatinib mesylate may affect blood clotting and increase the risk of bleeding or bruising. If you notice unusual bleeding, such as nosebleeds, blood in urine, or excessive bruising, seek medical attention immediately.
Some of the concerns you may have about the Veenat Capsule (Imatinib mesylate)
Can Imatinib mesylate (Veenat) be taken with other medications?
Answer: Imatinib mesylate can interact with certain medications, including strong CYP3A4 enzyme inhibitors and inducers. It is important to inform your healthcare provider about all medications, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements, to assess potential interactions and adjust dosages if necessary.
Can Imatinib mesylate Gleevec cause long-term side effects?
Answer: While Imatinib mesylate is generally well-tolerated, there is a possibility of long-term side effects. Regular monitoring of blood counts, liver function, and kidney function is necessary to detect any potential complications. It is important to discuss any concerns with your healthcare provider and report any persistent or severe symptoms.
Is it safe to consume alcohol while taking Imatinib mesylate?
Answer: Alcohol consumption should be limited or avoided while taking Imatinib mesylate. Alcohol may increase the risk of liver toxicity and worsen certain side effects. It is advisable to consult your healthcare provider for personalized advice regarding alcohol consumption during treatment.
Can Imatinib mesylate be used during pregnancy?
Answer: Imatinib mesylate has the potential to harm an unborn baby and is generally not recommended during pregnancy. It is important to discuss your pregnancy status with your healthcare provider before initiating treatment. They will evaluate the potential risks and benefits and may suggest alternative treatment options if necessary.
Can Imatinib mesylate be discontinued if the cancer is in remission?
Answer: The decision to discontinue Imatinib mesylate should be made in consultation with your healthcare provider. In some cases, it may be possible to discontinue the medication if the cancer is in remission. However, abrupt discontinuation without medical supervision can lead to a relapse. Your doctor will assess your specific situation and guide you on the appropriate course of action.
Potential Drug Connection with Veenat Capsule (Imatinib mesylate)
- Other Medications: Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Certain medications, such as strong CYP3A4 enzyme inhibitors (e.g., ketoconazole, clarithromycin) or inducers (e.g., rifampicin, phenytoin), may interact with Imatinib mesylate and affect its effectiveness or increase the risk of side effects.
- Grapefruit Juice: Avoid consuming grapefruit or grapefruit juice while taking Imatinib mesylate/Gleevec, as it may increase the concentration of the medication in your body and lead to an increased risk of side effects.
- CYP3A4 Substrates: Imatinib mesylate has the potential to interact with medications that are metabolized by the CYP3A4 enzyme. Examples of such drugs include simvastatin, lovastatin, and certain calcium channel blockers. Your healthcare provider will assess the potential risks and adjust dosages if necessary.
| Manufacturer | : | Natco Pharma, India |
| Equivalent Brand | : | Gleevec |
| Generic Search | : | Imatinib mesylate |
