Vegaz OD Tablet PR (Mesalazine)

Essential Safety Advice to Follow When Using Vegaz OD Tablet PR (Mesalazine)

• Hypersensitivity: If you've had a previous allergic reaction to Mesalazine or any of its components, inform your doctor before starting the medication.
• Pregnancy and Breastfeeding: Consult your healthcare provider before taking Mesalazine if you are pregnant, planning to become pregnant, or breastfeeding. The benefits and risks should be carefully considered.
• Renal Impairment: If you have kidney problems, your doctor may need to adjust the dosage of Mesalazine, as it's primarily eliminated through the kidneys.
• Liver Function: Individuals with liver disease or impaired liver function should be closely monitored while taking Mesalazine.
• Interaction with Other Medications: Inform your doctor about all the medications, including over-the-counter drugs and supplements, you are taking. Mesalazine may interact with certain drugs, potentially affecting their effectiveness or causing adverse effects.

Some of the specific indications for Vegaz OD Tablet PR (Mesalazine) include 

• Inflammatory Bowel Diseases (IBD): Mesalazine is primarily used for the treatment of ulcerative colitis and Crohn's disease, both of which are chronic inflammatory conditions that affect the gastrointestinal tract.
• Induction and Maintenance Therapy: It's used to induce remission during active flare-ups of IBD and to maintain remission during periods of lower disease activity.
• Localized Treatment: Rectal forms like Canasa Online, Sfrowasa, and Rowasa are especially effective for targeting inflammation in the rectum and lower colon.
• Off-Label Uses: Mesalazine might also be used off-label for other conditions involving inflammation in the digestive tract, as determined by a healthcare provider.
• Pediatric Use: In some cases, Mesalazine may be prescribed to children with certain forms of IBD, but the dosage and usage should be determined by a pediatric gastroenterologist.

Crucial Side Effects to Be Observed When Using Vegaz OD Tablet PR (Mesalazine)

• Common Side Effects: Commonly reported side effects include nausea, diarrhea, headache, abdominal pain, and flatulence. These side effects are usually mild and temporary.
• Allergic Reactions: In rare cases, Mesalazine can cause allergic reactions such as rash, itching, swelling, severe dizziness, and difficulty breathing. Seek immediate medical help if you experience these symptoms.
• Blood Disorders: Mesalazine may affect blood cell counts, leading to anemia or decreased white blood cell count. Regular blood tests may be required to monitor for these changes.
• Liver and Kidney Effects: Some individuals may experience changes in liver function or kidney function while taking Mesalazine. Regular monitoring is important, especially in those with pre-existing liver or kidney conditions.
• Lung Inflammation: Mesalazine has been associated with a rare side effect known as hypersensitivity pneumonitis, which involves inflammation of the lungs. Contact your healthcare provider if you experience unexplained respiratory symptoms.

Frequently Asked Queries About Vegaz OD Tablet PR (Mesalazine)

Can Mesalazine be taken during pregnancy?

Answer: Pregnant individuals should consult their doctor before taking Mesalazine. The benefits and risks will be evaluated, considering the health of both the mother and the baby.

Is Mesalazine the same as an antibiotic?

Answer: No, Mesalazine is not an antibiotic. It's an aminosalicylate medication that helps reduce inflammation in the digestive tract, commonly used for inflammatory bowel diseases.

Can I drink alcohol while on Mesalazine?

Answer: It's advisable to limit alcohol consumption while taking Mesalazine, as alcohol may interact with the medication and increase the risk of certain side effects.

Does Mesalazine cause weight gain?

Answer: Mesalazine is not typically associated with significant weight gain. If you notice any changes in weight while taking the medication, discuss it with your healthcare provider.

Can Mesalazine be crushed or split for easier ingestion?

Answer: It's important to follow your doctor's instructions regarding the administration of Mesalazine tablets. Crushing or splitting the tablets might alter the way the medication is released and absorbed, potentially affecting its effectiveness.

Combining different drugs with Vegaz OD Tablet PR (Mesalazine) can lead to Adverse Effects

• Azathioprine and 6-Mercaptopurine: Concurrent use of Mesalazine with these immunosuppressive drugs may increase the risk of bone marrow suppression.
• Warfarin: Mesalazine may interact with warfarin, an anticoagulant, potentially affecting blood clotting parameters. Regular monitoring is crucial.
• Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Combining Mesalazine with NSAIDs might increase the risk of gastrointestinal bleeding.
• Proton Pump Inhibitors (PPIs): PPIs could potentially reduce the effectiveness of Mesalazine, as they might alter the drug's release in the digestive tract.
• Lactulose or Other Acidic Substances: These substances might reduce the effectiveness of Mesalazine by affecting its dissolution and absorption in the intestines.