Hyponat-O Tablet (Tolvaptan)

Tolvaptan Tablet, marketed under the brand name Hyponat-O/Samsca, is a medication used in the treatment of hyponatremia, a condition characterized by low levels of sodium in the blood.

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Hyponat-O 15 Tablet (Tolvaptan 15mg)

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30 Tablet/s $68.10
60 Tablet/s $136.20
90 Tablet/s $204.30

Introduction of Hyponat-O Tablet (Tolvaptan)

Tolvaptan Tablet, marketed under the brand name Hyponat-O, is a medication used in the treatment of hyponatremia, a condition characterized by low levels of sodium in the blood. It belongs to a class of drugs known as selective vasopressin receptor antagonists. Tolvaptan works by increasing urine production and thereby correcting the imbalance of water and electrolytes in the body.

Dosage Information:

The dosage of Tolvaptan Tablet can vary depending on the individual's condition and the severity of hyponatremia. It is essential to follow the prescribed dosage and instructions provided by your healthcare professional. Typically, the recommended starting dose is 15 mg once daily. The dosage may be increased to 30 mg or 60 mg daily if necessary. It is important not to exceed the maximum daily dose of 60 mg.

It is crucial to take Tolvaptan Tablet with water, and it can be taken with or without food. Swallow the tablet whole without crushing or chewing it. If you miss a dose, take it as soon as you remember, but if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

Tolvaptan Medication: Tolvaptan is a prescription medication and should only be used under the guidance of a healthcare professional. It is essential to inform your doctor about any other medications you are taking, as well as any underlying medical conditions, to ensure the safe and effective use of Tolvaptan.

Tolvaptan Tablets Online at 1mgstore.com:

1mgstore.com is an online platform where you can find Tolvaptan tablets for purchase. It provides a convenient way to order medication from the comfort of your home. However, it is crucial to ensure that you are purchasing medications from a reputable and licensed source. Always check the credentials and reviews of the online store before making a purchase to ensure the authenticity and quality of the product.

Tolvaptan Tablets Price:

The price of Tolvaptan tablets can vary depending on various factors such as the brand, dosage strength, and the number of tablets purchased. It is advisable to compare prices from different sources, including local pharmacies and online platforms, to get the best deal. Additionally, some insurance plans may cover a portion of the cost of Tolvaptan tablets, so it is recommended to check with your insurance provider for any available coverage.

In conclusion, Tolvaptan Tablet (Hyponat-O) is a medication used for the treatment of hyponatremia and associated conditions. It helps to restore the balance of sodium and water in the body, relieving symptoms related to fluid retention. The dosage should be followed as prescribed by a healthcare professional, and it is important to purchase medications from reputable sources. Always consult with your doctor for personalized advice and guidance regarding the use of Tolvaptan or any other medication.

Samsca Online: Samsca is another brand name for Tolvaptan. It may be available for purchase online through various platforms. However, it is essential to exercise caution when purchasing medications online and ensure that you are buying from a reputable and licensed source. Verify the authenticity and quality of the product, and consider consulting with your healthcare provider before making an online purchase.

Hormone Secretion: Tolvaptan works by selectively blocking the action of vasopressin, a hormone responsible for regulating water balance in the body. Vasopressin acts on the kidneys, causing them to reabsorb water and concentrate urine. By inhibiting the effects of vasopressin, Tolvaptan increases urine output, which helps to eliminate excess water from the body.

This mechanism of action makes Tolvaptan particularly useful in conditions where there is excessive hormone secretion, such as the syndrome of inappropriate antidiuretic hormone secretion (SIADH). SIADH is characterized by the excessive release of vasopressin, leading to water retention and dilutional hyponatremia. Tolvaptan helps to correct this imbalance by blocking the effects of vasopressin and promoting diuresis.

In conclusion, Tolvaptan Tablet (Hyponat-O) is a medication used to treat hyponatremia and associated conditions. Precautions should be taken, including informing your healthcare provider about allergies, kidney or liver problems, and following fluid intake restrictions if advised. Tolvaptan can interact with certain drugs, so it is important to disclose all medications being taken. Side effects may occur, ranging from mild to severe, and immediate medical attention should be sought if serious side effects manifest. Tolvaptan can be purchased online under various brand names like Samsca, but caution should be exercised to ensure authenticity. By blocking the effects of vasopressin, Tolvaptan helps correct hormone secretion imbalances in conditions like SIADH. Always consult with your healthcare provider for personalized advice and guidance when using Tolvaptan or any other medication.

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When using Tolvaptan Tablet (Hyponat-O), it is important to be aware of certain precautions:

Allergies: Inform your healthcare provider if you have any known allergies to Tolvaptan or any other medications. It is essential to check the ingredients of the medication to avoid any potential allergic reactions.

Kidney and liver problems: Individuals with kidney or liver problems may require dose adjustments or special monitoring while taking Tolvaptan. It is important to inform your doctor about any pre-existing kidney or liver conditions before starting the medication.

Fluid restriction: In some cases, your doctor may advise you to restrict fluid intake while taking Tolvaptan. Follow your doctor's instructions regarding fluid intake and ensure regular monitoring of sodium levels in the blood.

Pregnancy and breast-feeding: Tolvaptan/Samsca is not recommended for use during pregnancy, as its safety in pregnant women has not been established. It is also not known whether Tolvaptan passes into breast milk, so breastfeeding should be avoided while using this medication.

Older adults: Older adults may be more susceptible to the effects of Tolvaptan, especially related to changes in blood pressure and fluid balance. Close monitoring is necessary in this population to minimize the risk of adverse effects.

Sodium levels: Regular monitoring of sodium levels in the blood is essential during Tolvaptan therapy. This ensures that sodium levels are maintained within the appropriate range and prevents overcorrection, which can lead to complications.

Some Of The Potential Application Of the Tolvaptan Tablet

Tolvaptan Tablet is primarily used for the treatment of hyponatremia associated with certain conditions such as the syndrome of inappropriate antidiuretic hormone secretion (SIADH) or heart failure. It helps to increase blood sodium levels and restore the balance of electrolytes in the body. By increasing urine output, Tolvaptan helps to eliminate excess water from the body, thereby relieving symptoms associated with fluid retention.

Tolvaptan/Samsca may also be prescribed in the management of autosomal dominant polycystic kidney disease (ADPKD). It is believed to slow down the progression of kidney cysts and reduce the risk of associated complications in patients with this condition.

Tolvaptan tablets may cause side effects in some individuals. Common side effects include:

Dry mouth and thirst
Increased urination
Weakness or fatigue
Dizziness or lightheadedness
Constipation or diarrhea
Headache
Nausea or vomiting


These side effects are generally mild and resolve on their own. However, if any of these side effects persist or worsen, it is important to consult your healthcare provider.

Serious side effects are rare but can occur. If you experience any of the following, seek immediate medical attention:

Signs of dehydration, such as extreme thirst, dry skin, and dark-colored urine
Rapid weight loss
Irregular heartbeat or chest pain
Severe dizziness or fainting
Confusion or changes in mental status
Severe abdominal pain or bloating


It is important to note that this is not an exhaustive list of side effects. If you experience any unusual symptoms while taking Tolvaptan, it is crucial to inform your healthcare provider promptly.

Can I take Tolvaptan Tablet if I have a history of kidney disease?

If you have a history of kidney disease, it is important to inform your healthcare provider before taking Tolvaptan Tablet. They will evaluate your kidney function and determine if Tolvaptan is suitable for you. In some cases, dose adjustments or alternative treatment options may be considered to ensure the safe use of the medication.

Can Tolvaptan/Samsca be used for the treatment of congestive heart failure?

Yes, Tolvaptan can be used as part of the treatment for congestive heart failure. It helps to relieve symptoms associated with fluid retention by increasing urine output and reducing the excess fluid in the body. However, the use of Tolvaptan in congestive heart failure should be carefully monitored by a healthcare professional to ensure optimal management of the condition.

Can Tolvaptan cause electrolyte imbalances?

Tolvaptan can affect electrolyte levels, including sodium and potassium, in the body. While it is primarily used to correct low sodium levels, there is a possibility of developing electrolyte imbalances. Regular monitoring of electrolyte levels is important during Tolvaptan therapy to ensure that the levels remain within the appropriate range. Your healthcare provider will guide you on any necessary dietary adjustments or additional measures to maintain electrolyte balance.

Are there any specific food or drug interactions with Tolvaptan?

Tolvaptan can interact with certain foods and medications. Grapefruit and grapefruit juice should be avoided while taking Tolvaptan, as they can increase the concentration of the medication in the body and potentially lead to an increased risk of side effects. Additionally, it is important to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions. They will assess any possible interactions and adjust your treatment plan accordingly.

Can Tolvaptan be used in children?

Tolvaptan is not typically recommended for use in children. The safety and effectiveness of Tolvaptan in pediatric patients have not been established. It is primarily indicated for adults with specific conditions such as hyponatremia, syndrome of inappropriate antidiuretic hormone secretion (SIADH), and autosomal dominant polycystic kidney disease (ADPKD). If Tolvaptan is being considered for a child, it should be under the careful supervision of a pediatric specialist who can assess the potential risks and benefits on a case-by-case basis.

Drug Interconnection of Hyponat-O Tablet (Tolvaptan)

Tolvaptan may interact with other medications, leading to changes in their effectiveness or increasing the risk of side effects. It is important to inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Some notable drug interactions with Tolvaptan include:

CYP3A4 inhibitors: Tolvaptan is metabolized by the CYP3A4 enzyme. Co-administration of strong CYP3A4 inhibitors, such as ketoconazole or ritonavir, can increase the concentration of Tolvaptan in the body, leading to an increased risk of side effects. Dose adjustments or alternative medications may be necessary in such cases.

CYP3A4 inducers: Concurrent use of strong CYP3A4 inducers, such as rifampin or carbamazepine, can decrease the concentration of Tolvaptan, reducing its effectiveness. Your doctor may need to adjust the Tolvaptan dosage or consider alternative treatment options.

Diuretics: Combining Tolvaptan/Samsca with diuretic medications may enhance the diuretic effect, leading to excessive fluid loss and electrolyte imbalances. Close monitoring of fluid and electrolyte levels is crucial when using Tolvaptan with diuretics.

Other medications: Certain medications that affect hormone secretion, such as vasopressin analogs or desmopressin, may interact with Tolvaptan. It is important to inform your doctor about any medications or hormonal therapies you are currently using to avoid potential interactions.

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Manufacturer:Zydus Cadila
Equivalent Brand:Samsca
Generic Search:Tolvaptan