Licab Tablet (Lithium Carbonate)
Product Overview
Licab Tablet contains Lithium Carbonate, a well-established mood stabilizer primarily used in the management of bipolar disorder. It helps in controlling acute manic episodes and reducing the frequency and severity of mood swings over long-term treatment.
Lithium works by stabilizing neuronal signaling pathways in the brain, making it a cornerstone therapy in psychiatric practice for mood regulation. Due to its narrow therapeutic index, it requires careful dose adjustment and regular monitoring.
Mechanism Insights (How It Works)
- Neurotransmitter Modulation
Lithium influences multiple neurotransmitter systems including dopamine, serotonin, and glutamate, helping stabilize mood fluctuations. - Second Messenger Regulation
It inhibits inositol monophosphatase, reducing overactive inositol phosphate signaling, which contributes to manic symptoms. - Neuroprotective Effects
Lithium also modulates enzymes like glycogen synthase kinase-3 (GSK-3), supporting neuronal resilience and long-term brain stability.
Administration Guidelines
- Take exactly as prescribed by the physician
- Maintain consistent timing of doses daily
- Do not abruptly stop the medication
- Stay well-hydrated during therapy
- Regular blood tests for lithium levels, kidney function, and thyroid function are essential
- Avoid sudden dietary sodium changes (can affect lithium levels)
Clinical Considerations
- Requires close therapeutic monitoring due to narrow safety margin
- Highly effective in preventing relapse in bipolar disorder
- Onset of full mood-stabilizing effect may take several days to weeks
- Dose adjustments are common based on serum lithium levels
- Overdose risk can lead to toxicity (tremor, confusion, renal impairment)
- Long-term use may affect thyroid and kidney function, requiring periodic evaluation
Precautions:
Licab Tablet contains Lithium Carbonate, a mood stabilizer with a narrow therapeutic range. It must be used with strict medical supervision to ensure safe and effective treatment, especially in patients with bipolar disorder and related conditions.
General Precautions
- Use only under the supervision of a qualified healthcare professional
- Do not adjust dose or stop suddenly without medical advice
- Regular blood level monitoring is essential due to narrow therapeutic index
- Take consistently at the same time each day
- Avoid self-medication or sharing this medicine with others
Kidney Function Considerations
- Lithium is primarily excreted through the kidneys
- Use cautiously in patients with kidney impairment
- Periodic kidney function tests are required during long-term therapy
- Risk of toxicity increases if kidney function declines
Thyroid Function Monitoring
- Lithium may affect thyroid activity
- Regular thyroid function tests are recommended
- Watch for signs of hypothyroidism (fatigue, weight gain, cold intolerance)
- Dose adjustment may be needed if thyroid imbalance occurs
Hydration & Salt Balance
- Maintain adequate fluid intake daily
- Avoid dehydration (especially during fever, vomiting, diarrhea, or heavy exercise)
- Sudden changes in salt (sodium) intake can affect lithium levels
- Excess sweating may increase risk of toxicity
Drug Interactions
- Use caution with NSAIDs (e.g., ibuprofen), diuretics, and ACE inhibitors
- These medicines can increase lithium levels and toxicity risk
- Always inform your doctor about all ongoing medications
Pregnancy & Breastfeeding
- Not recommended during pregnancy unless clearly necessary
- May increase risk of fetal heart defects, especially in the first trimester
- Use only if benefits outweigh risks under strict medical supervision
- Avoid breastfeeding unless advised by a doctor
Signs of Lithium Toxicity (Important Warning)
Seek immediate medical help if symptoms appear:
- Tremors, confusion, or drowsiness
- Severe nausea, vomiting, or diarrhea
- Unsteady walking or muscle weakness
- Slurred speech
Usage
Side Effects
General Safety Information
Licab Tablet contains Lithium Carbonate, a mood stabilizer commonly used in the treatment of bipolar disorder. It helps control mood swings by balancing brain chemicals.
Lithium has a narrow therapeutic range, meaning the difference between effective and toxic levels is small. Therefore, it must always be used under strict medical supervision with regular blood level monitoring.
Most side effects are dose-related and may reduce after dose adjustment.
Common Side Effects
✔ Fine hand tremors
✔ Increased thirst
✔ Increased urination
✔ Nausea or mild stomach upset
✔ Weight gain
✔ Mild fatigue or weakness
✔ Mild diarrhea
These effects are usually manageable and may improve over time or with dose adjustment.
Serious Side Effects (Rare but Important)
⚠ Seek immediate medical attention if you experience:
- Severe tremors or muscle twitching
- Confusion, drowsiness, or difficulty speaking
- Unsteady walking or poor coordination
- Severe vomiting or persistent diarrhea
- Irregular heartbeat or chest discomfort
- Signs of lithium toxicity (blurred vision, ringing in ears, severe weakness)
- Swelling of hands/feet or significant weight changes
Risk Factors & Monitoring
- Higher risk in kidney or thyroid disorders
- Dehydration, low salt intake, or excessive sweating can increase toxicity risk
- Requires regular blood level monitoring of lithium
- Periodic checks of kidney function and thyroid function are essential
- Dose adjustments are often needed based on blood reports
FAQs
What is Licab Tablet used for?
Licab Tablet contains Lithium Carbonate and is mainly used to treat and manage bipolar disorder (manic-depressive illness). It helps stabilize mood, reducing episodes of mania and depression.
How does Licab Tablet work in the body?
It works by affecting the balance of certain brain chemicals (neurotransmitters) such as serotonin and norepinephrine. This helps stabilize mood swings and reduces extreme emotional states.
Can Licab Tablet be used for children?
Yes, in some cases it may be prescribed to children or adolescents, but only under strict psychiatric supervision with careful monitoring of blood levels and kidney/thyroid function.
How should I take Licab Tablet?
It should be taken exactly as prescribed by your doctor. It is usually taken with food to reduce stomach upset. Regular blood tests are often required to ensure safe and effective levels in the body.
What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed one. Do not take a double dose to make up for it.
Interactions
General Interaction Overview
Licab Tablet contains Lithium Carbonate, a mood stabilizer commonly used in bipolar disorder. Lithium has a narrow therapeutic range, meaning small changes in blood levels can lead to reduced effectiveness or toxicity.
Because of this, many medicines and even changes in salt or fluid balance can significantly affect how lithium works in the body.
It is very important to inform your healthcare provider about all prescription drugs, over-the-counter medicines, and supplements you are taking.
Commonly Reported Interactions
- Diuretics (water tablets) such as hydrochlorothiazide or furosemide
→ Can increase lithium levels, raising risk of toxicity - NSAIDs (painkillers) like ibuprofen, diclofenac, indomethacin
→ May reduce lithium elimination, increasing blood concentration
Important Note
Even small changes in hydration, kidney function, or medication can affect lithium levels. Regular blood tests are essential to ensure safe and effective treatment.
Always consult your doctor before starting or stopping any medicine while on Licab Tablet.
| Manufacturer | : | Torrent Pharma, India |
| Equivalent Brand | : | Eskalith |
| Generic Search | : | Lithium Carbonate |















