Nelvir Tablet (Nelfinavir Mesylate)

Nelfinavir Tablet, commonly known by its brand name Nelvir and Viracept, is a prescription medication used in the treatment of Human Immunodeficiency Virus (HIV) infection.

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Nelvir 250mg Tablet (Nelfinavir Mesylate 250mg)

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100 Tablet/s $80.00
200 Tablet/s $160.00
300 Tablet/s $240.00

Introduction to Nelfinavir Tablet (Nelvir)

Nelfinavir Tablet, commonly known by its brand name Nelvir and Viracept, is a prescription medication used in the treatment of Human Immunodeficiency Virus (HIV) infection. It belongs to the class of drugs known as protease inhibitors, which work by blocking an enzyme called protease that is essential for the replication of the HIV virus. By inhibiting this enzyme, Nelfinavir helps to reduce the viral load in the body and slow down the progression of the disease. Nelfinavir has been an essential component of antiretroviral therapy (ART) regimens for many HIV-positive individuals and has played a significant role in improving the quality of life and life expectancy for those living with HIV.

Dosage Information for Nelfinavir Tablet (Nelvir)

The dosage of Nelfinavir Tablet may vary depending on individual factors such as the patient's age, weight, and other medical conditions. It is crucial to follow the doctor's prescription and dosing instructions carefully. Nelfinavir is typically available in 250 mg and 625 mg tablets. The usual recommended dosage for adults is 1250 mg (five 250 mg tablets) twice daily or 750 mg (three 250 mg tablets) three times daily. It is important to take Nelfinavir with food to enhance its absorption and effectiveness. For pediatric patients, the dosage is calculated based on body weight. The recommended dose is 20 to 30 mg per kilogram of body weight, taken two to three times daily with food. Dosage adjustments may be necessary for patients with liver or kidney impairment. It is essential to adhere to the prescribed dosing schedule and not miss any doses to ensure the maximum benefit from Nelfinavir therapy.

Nelfinavir Medication: Nelfinavir is available in tablet form and is taken orally. It is easily absorbed when administered with food, making it a convenient and effective medication in the treatment of HIV.

Nelfinavir Prescription: Nelfinavir is a prescription-only medication, meaning it can only be obtained with a valid prescription from a licensed healthcare provider. The prescription ensures that the drug is used appropriately and safely and that patients receive the proper dosage and guidance during treatment.

Nelfinavir HIV Treatment Resistance: Over time, some HIV strains may develop resistance to Nelfinavir or other antiretroviral drugs. This highlights the importance of strict adherence to the prescribed treatment regimen and close monitoring of viral load and CD4 T-cell counts to detect any potential resistance early. In case of treatment failure or resistance development, alternative antiretroviral regimens may be required.

Nelfinavir HIV Treatment Availability: Nelfinavir has been available since the late 1990s and has been an essential component of HIV treatment. While newer antiretroviral drugs have been developed, Nelfinavir remains a valuable option in certain situations, particularly for patients who cannot tolerate other medications or have developed resistance to other drug classes.

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Some of the important Safety Advice to be taken while using Nelvir Tablet (Nelfinavir)

  • Medical History: Before initiating treatment with Nelfinavir/Viracept, it is crucial for patients to disclose their complete medical history to the healthcare provider. Inform them about any pre-existing medical conditions, including liver or kidney problems, diabetes, heart disease, bleeding disorders, or any allergies to medications.
  • Pregnancy and Breastfeeding: Pregnant or breastfeeding individuals should exercise caution when using Nelfinavir. The drug's safety during pregnancy has not been well-established, and it may pass into breast milk, potentially harming the nursing infant. Healthcare providers will carefully assess the risks and benefits before prescribing Nelfinavir to pregnant or breastfeeding individuals.
  • Children and Adolescents: Nelfinavir may be prescribed to pediatric patients; however, the dosage and usage guidelines may differ from those for adults. Pediatric patients should be closely monitored for any side effects or adverse reactions.
  • Concomitant Medications: Patients should inform their healthcare providers about all medications, supplements, or herbal products they are taking, as certain drugs may interact with Nelfinavir, leading to adverse effects or reduced efficacy. A comprehensive medication review can help prevent potential drug interactions.
  • Liver and Kidney Function: Individuals with impaired liver or kidney function may require dosage adjustments or careful monitoring while using Nelfinavir. Close monitoring of liver and kidney function tests is essential to ensure the drug's safe and effective use.
  • Cardiovascular Risk: Nelfinavir may be associated with an increased risk of cardiovascular events, such as heart attack or stroke. Patients with a history of cardiovascular disease or risk factors should be closely monitored during treatment.
  • Diabetes Risk: Nelfinavir may cause elevated blood sugar levels and worsen diabetes or trigger the onset of diabetes in susceptible individuals. Regular monitoring of blood glucose levels is recommended for diabetic patients.
  • Immune Reconstitution Syndrome (IRS): In some HIV-infected patients with advanced immune suppression, the initiation of antiretroviral therapy, including Nelfinavir, may trigger immune reconstitution syndrome. This condition involves an inflammatory response to previously hidden infections, necessitating close medical supervision during the initial phase of treatment.

Some of the specific indications for Nelfinavir Tablet (Nelvir) include

HIV Treatment: Nelfinavir/Viracept is a Life-Saving Drug primarily used in the management of HIV infection as part of combination antiretroviral therapy (ART). When used in combination with other antiretroviral drugs, Nelfinavir helps suppress viral replication, reduce viral load, and increase the number of CD4 T-cells, which are crucial for a healthy immune system. This leads to improved immune function and reduced risk of opportunistic infections, thus prolonging the overall survival and improving the quality of life for HIV-positive individuals.

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For individuals prescribed Nelfinavir Tablet, the medication can be conveniently purchased at 1mgstore.com. It is essential to ensure the authenticity and reliability of the online pharmacy before making any purchases. Always consult with a healthcare professional before starting or changing any HIV treatment regimen and follow their guidance throughout the course of therapy.

Important Adverse effects of using Nelvir Tablet (Nelfinavir) must be noticed

  • Gastrointestinal Disturbances: The most common side effects of Nelfinavir include diarrhea, nausea, vomiting, abdominal discomfort, and flatulence. These symptoms can usually be managed by taking the medication with food.
  • Metabolic Changes: Nelfinavir/Viracept may cause lipid abnormalities, including elevated cholesterol and triglyceride levels. Regular monitoring of blood lipids is important, especially in patients with existing lipid disorders.
  • Skin Reactions: Some individuals may experience skin rashes or hypersensitivity reactions while taking Nelfinavir. If any skin reaction occurs, patients should seek immediate medical attention.
  • Liver and Pancreatic Effects: Nelfinavir may cause liver enzyme elevations or, rarely, liver toxicity. Additionally, there have been reports of pancreatitis associated with the use of Nelfinavir. Regular liver function tests are recommended during treatment.
  • Immune System Reactions: Like other antiretroviral drugs, Nelfinavir may lead to immune reconstitution syndrome (IRS) in some patients, where the body's immune system mounts an inflammatory response against previously unrecognized infections.
  • Cardiovascular Events: There is a potential association between the use of Nelfinavir and an increased risk of cardiovascular events, such as heart attack or stroke.
  • Hemorrhage: Nelfinavir may interfere with blood clotting mechanisms, leading to an increased risk of bleeding in susceptible individuals.
  • Insulin Resistance and Diabetes: Nelfinavir may cause insulin resistance, leading to elevated blood sugar levels and, in some cases, the onset of diabetes.

Frequently Asked Questions (FAQs) about Nelfinavir Tablet (Nelvir)

Can I stop taking Nelfinavir if I start feeling better?

No, it is essential to continue taking Nelfinavir as prescribed by your doctor, even if you start feeling better. Stopping the medication prematurely can lead to the resurgence of the virus and the development of drug resistance.

Can Nelfinavir/Viracept be taken with food supplements?

Some food supplements may interact with Nelfinavir and affect its efficacy. It's crucial to inform your healthcare provider about all supplements you are taking to ensure there are no potential interactions.

Are there any specific storage instructions for Nelfinavir tablets?

Nelfinavir tablets should be stored in a dry place at room temperature, away from direct sunlight and moisture. Keep them out of the reach of children and do not use the medication beyond its expiration date.

Can Nelfinavir cure HIV completely?

Nelfinavir is not a cure for HIV. It is an antiretroviral medication that helps control the virus's replication and slow disease progression. Long-term and consistent use, along with a combination of other antiretroviral drugs, is necessary to manage HIV effectively.

What should I do if I miss a dose of Nelfinavir?

If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for the missed one. Consult your doctor if you are unsure about the best course of action.

Important Drug Interconnections with Nelvir Tablet (Nelfinavir) must be noticed

  • Other Antiretroviral Drugs: Nelfinavir is often used in combination with other antiretroviral medications. However, certain drug combinations may lead to interactions or alter the blood levels of either drug. Healthcare providers will carefully select the appropriate combination of drugs and monitor for potential interactions.
  • Medications Metabolized by the Liver: Nelfinavir is metabolized by the liver's cytochrome P450 enzyme system. Therefore, drugs that are also metabolized by this system may interact with Nelfinavir, leading to changes in blood levels and potentially affecting efficacy or safety.
  • St. John's Wort: The herbal supplement St. John's Wort may decrease Nelfinavir's effectiveness by inducing enzymes that break down the drug. Patients should avoid taking this supplement during Nelfinavir treatment.
  • Protease Inhibitors and CYP3A4 Inhibitors: Co-administration of Nelfinavir/Viracept with other protease inhibitors or drugs that inhibit the CYP3A4 enzyme may increase Nelfinavir levels, leading to potential side effects. Dose adjustments may be necessary in such cases.
  • Anticoagulants: Nelfinavir may interact with anticoagulant medications, such as warfarin, leading to an increased risk of bleeding. Close monitoring of blood clotting parameters is essential in patients receiving both drugs.
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Manufacturer:Cipla Pharma, India
Equivalent Brand:Viracept
Generic Search:Nelfinavir Mesylate