Phenergan Tablet (Promethazine) | Used for Allergies, Nausea, Vomiting & Motion Sickness
Phenergan Tablet contains Promethazine Hydrochloride , a sedating antihistamine with antiemetic properties. It is used to relieve allergic conditions such as hay fever and hives and to prevent or treat nausea and vomiting, including travel sickness. It may also be used for certain short-term sedative purposes according to the product information.
Product Overview
Phenergan Tablet contains Promethazine Hydrochloride, a phenothiazine-derived antihistamine that has antihistamine, antiemetic, sedative and anticholinergic properties. The 25mg tablet formulation is used for allergic conditions and for preventing or treating nausea and vomiting, including motion sickness. Some product labeling also includes short-term treatment of insomnia in adults and short-term sedation in children aged 6 years and above.
Promethazine works mainly by blocking the effects of histamine. It also acts on pathways in the brain involved in nausea and vomiting. Because it enters the brain, it can cause significant drowsiness and reduced alertness.
Key Points
- Contains Promethazine Hydrochloride 25mg.
- Belongs to the sedating antihistamine group.
- Helps relieve allergy symptoms.
- Used for nausea and vomiting.
- Can help prevent travel or motion sickness.
- May be used for vertigo-related nausea.
- Can cause drowsiness and dizziness.
- Avoid alcohol while taking it.
- Do not drive if it makes you sleepy or dizzy.
Product Information
| Product Information | Details |
| Product Name | Phenergan Tablet |
| Active Ingredient | Promethazine Hydrochloride |
| Dosage Form | Tablet |
| Drug Class | Phenothiazine / sedating antihistamine |
| Therapeutic Action | Antihistamine and antiemetic |
| Main Uses | Allergies, nausea, vomiting and motion sickness |
Route of Administration | Oral |
How Does Phenergan Tablet Work?
Phenergan contains Promethazine, which blocks histamine H1 receptors and reduces the effects of histamine involved in allergic reactions. It also affects brain pathways associated with nausea and vomiting, giving it an antiemetic effect.
Because Promethazine enters the brain, it can produce sedation and drowsiness. This is why caution is required when driving and when taking other medicines that cause sleepiness.
Precaution
1. Use Only as Recommended
Take Phenergan Tablet exactly as directed by your doctor, pharmacist or the product instructions. Do not increase the dose yourself.
2. Check for Allergies
Do not use Phenergan if you are allergic to Promethazine, other phenothiazines or any ingredient in the formulation.
3. Children Under 6 Years
The UK Phenergan 25mg tablet product information states that it should not be used in children under 6 years. Age-specific formulations and instructions should always be checked.
4. Drowsiness
Promethazine can cause considerable drowsiness, reduced alertness and dizziness. Avoid activities requiring full concentration if affected.
5. Driving and Machinery
Do not drive, cycle or operate machinery if Phenergan makes you sleepy, dizzy or less alert.
6. Avoid Alcohol
Alcohol can increase the sedative effects of Promethazine and may make you excessively sleepy or impair coordination.
7. Breathing Problems
Tell your doctor if you have asthma, bronchitis, wheezing or another respiratory condition before using Phenergan.
8. Epilepsy
Inform your healthcare professional if you have epilepsy or another seizure disorder before taking Promethazine.
Usage
Phenergan Tablet should be taken by mouth according to the product instructions or healthcare professional's advice. The appropriate dose depends on the reason for treatment and the patient's age.
For the 25mg Phenergan tablet, the UK product information states that adults and children over 10 years taking it for motion sickness may take 25mg the night before the journey, with another dose after 6–8 hours if required. For allergy symptoms, adults and children over 10 years may start with 25mg at night, with a maximum of 25mg twice daily according to the product information.
Do not exceed the recommended dose. Phenergan should generally not be used for longer than the period recommended in the product instructions without medical advice.
Uses
1. Allergy Symptoms
Phenergan Tablet is used to relieve symptoms of allergic conditions such as hay fever, allergic rhinitis, hives and certain skin rashes.
2. Nausea
Promethazine can help relieve nausea associated with certain conditions.
3. Vomiting
Phenergan has antiemetic properties and can be used to prevent or relieve vomiting.
4. Motion Sickness
Phenergan is used to prevent and treat nausea and vomiting caused by travel or motion sickness.
5. Vertigo-Related Nausea
Promethazine may help relieve nausea and vomiting associated with vertigo.
Side Effects
Common Side Effects
Possible side effects of Phenergan Tablet include:
- Drowsiness
- Dizziness
- Headache
- Dry mouth
- Blurred vision
- Constipation
- Fatigue
Serious Side Effects
Seek urgent medical attention if you develop:
- Difficulty breathing
- Severe allergic reaction
- Swelling of the face, lips, tongue or throat
- Severe confusion or loss of consciousness
- Seizures
- Severe or uncontrolled movements
- Significant changes in heart rhythm
FAQs
1. What is Phenergan Tablet?
Phenergan Tablet is a medicine containing Promethazine Hydrochloride, a sedating antihistamine with antiemetic properties.
2. What is the active ingredient in Phenergan Tablet?
The active ingredient is Promethazine Hydrochloride. The Phenergan 25mg tablet contains 25mg of promethazine hydrochloride.
3. What is Phenergan Tablet used for?
It is used for allergic conditions, nausea, vomiting and motion sickness. Some product information also includes short-term insomnia in adults and short-term sedation in children aged 6 years and above.
4. How does Phenergan work?
Promethazine blocks histamine H1 receptors and also affects brain pathways involved in nausea and vomiting. It can therefore provide antihistamine and antiemetic effects.
5. Does Phenergan cause drowsiness?
Yes. Promethazine is a sedating antihistamine and can cause sleepiness, dizziness and reduced alertness.
6. Can Phenergan be used for motion sickness?
Yes. Phenergan is used to prevent and treat motion sickness. For the 25mg tablet, the product information recommends taking a dose the night before travel for prevention.
7. Can Phenergan be used for allergies?
Yes. It can be used for allergic conditions such as hay fever, allergic rhinitis, hives and certain skin rashes.
Interactions
1. Alcohol
Alcohol can significantly increase the sedative effects of Promethazine. Avoid alcohol while taking Phenergan.
2. Sleeping Medicines
Sleeping tablets and other sedatives may increase drowsiness when taken with Phenergan.
3. Opioid Painkillers
Opioids can increase central nervous system depression and sedation when combined with Promethazine.
4. Antidepressants
Certain antidepressants can interact with Promethazine and may increase sedative or anticholinergic effects.
5. MAO Inhibitors
MAO inhibitors are particularly important because the Phenergan product information advises avoiding them during treatment and for 14 days after stopping an MAOI.
6. Other Antihistamines
Taking other sedating antihistamines can increase drowsiness and other side effects.
7. Anticholinergic Medicines
Medicines with anticholinergic effects may increase dry mouth, blurred vision, constipation and difficulty passing urine.
8. Antipsychotic Medicines
Other phenothiazines and certain antipsychotic medicines may increase the risk of additive adverse effects.
| Manufacturer | : | Abbott India |
| Equivalent Brand | : | Phenergan |
| Generic Search | : | promethazine hydrochloride |
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