Soranib Tablet (Sorafenib)

Sorafenib tablet, marketed under the brand name Soranib, and Nexavar, is a medication used in the treatment of certain types of cancer.

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Soranib 200mg Tablet (Sorafenib 200mg)

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120 Tablet/s $150.00
240 Tablet/s $300.00
360 Tablet/s $450.00

Introduction to Sorafenib Tablet (Soranib):

Sorafenib tablet, marketed under the brand name Soranib, is a medication used in the treatment of certain types of cancer. It belongs to a class of drugs known as multikinase inhibitors, which work by interfering with the growth and spread of cancer cells in the body. Soranib contains the active ingredient sorafenib tosylate, which inhibits the activity of certain proteins involved in cancer cell proliferation and blood vessel formation. Sorafenib tablet (Soranib) is a powerful Anti-Cancer medication that can be a Life-Saving Drug for patients with renal cell carcinoma and hepatocellular carcinoma. Nexavar is another brand name for Sorafenib.

Dosage Information:

The dosage of Soranib (Sorafenib tablet) may vary depending on the specific type of cancer being treated and individual patient factors. It is crucial to follow the prescribed dosage and directions given by your healthcare provider. Soranib tablets are usually taken orally, with or without food. The tablets should be swallowed whole with a glass of water, and it is important not to crush, chew, or break them. The recommended dose of Soranib for most adult patients with renal cell carcinoma or hepatocellular carcinoma is typically 400 mg (two tablets of 200 mg) taken twice daily. The treatment duration may vary depending on the response to the medication and the overall health of the patient. It is essential to adhere to the prescribed schedule and not skip or alter the dosage without consulting a healthcare professional.

Sorafenib Tablet Benefits:

Sorafenib tablet (Soranib) offers several benefits in the treatment of renal cell carcinoma and hepatocellular carcinoma:

Prolonged Survival: Soranib has demonstrated the potential to extend overall survival rates in patients with advanced kidney and liver cancers, compared to traditional treatment options.

Delayed Disease Progression: The medication has shown efficacy in slowing down the growth and spread of cancer cells, helping to delay disease progression and improve quality of life.

Multikinase Inhibition: Soranib targets multiple kinases, enzymes that play a crucial role in cancer cell growth and blood vessel formation. By inhibiting these kinases, the drug impedes the progression of the disease.

Oral Administration: Soranib/Nexavar is available in tablet form, making it convenient for patients to take at home. This eliminates the need for frequent hospital visits and allows for more flexible treatment schedules.

Sorafenib Tablet Manufacturer: Cipla Pharma, India

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Some Of The Precautionary Measures to be taken while using the Soranib Tablet (Sorafenib)

  • Medical History: Before starting treatment with Sorafenib, it is crucial to inform your healthcare provider about your complete medical history, including any pre-existing conditions such as heart problems, bleeding disorders, high blood pressure, or kidney disease. These factors may affect the safety and efficacy of the medication.
  • Pregnancy and Breastfeeding: Sorafenib can cause harm to an unborn baby, and therefore, it is not recommended for use during pregnancy. It is important to use effective contraception while taking Soranib and discuss family planning options with your healthcare provider. Similarly, it is advised not to breastfeed while on Soranib treatment due to the potential risk to the infant.
  • Hypertension: Sorafenib/Nexavar may cause an increase in blood pressure. Regular monitoring of blood pressure is necessary during treatment. If hypertension occurs, appropriate medications may be prescribed to manage it.
  • Wound Healing: Sorafenib can interfere with the normal healing process. If you have undergone recent surgery or are scheduled for surgery, it is important to inform your surgeon about your Soranib treatment. Your healthcare provider may advise temporary discontinuation of Soranib before and after surgery.
  • Thyroid Function: Sorafenib can affect thyroid function, leading to hypothyroidism or hyperthyroidism. Regular thyroid function tests are recommended during treatment, and appropriate thyroid hormone replacement therapy may be prescribed if necessary.

Soranib (Sorafenib tablet) is primarily used for the treatment of two types of cancer:

Renal Cell Carcinoma: Soranib/Nexavar is indicated for the treatment of advanced renal cell carcinoma, a type of kidney cancer. It helps to slow down the growth and spread of cancer cells, potentially prolonging survival and improving overall outcomes for patients.

Hepatocellular Carcinoma: Soranib is also approved for the treatment of advanced hepatocellular carcinoma, the most common type of liver cancer. It can help in delaying the progression of the disease and improve survival rates.

Potential Secondary effects of Soranib (Sorafenib tablet)

Soranib (Sorafenib tablet) can cause various side effects, which may vary in severity and frequency among individuals. It is important to be aware of these potential side effects and promptly inform your healthcare provider if you experience any of the following:

  • Gastrointestinal Issues: Common gastrointestinal side effects of Soranib include diarrhea, nausea, vomiting, abdominal pain, and loss of appetite. These symptoms can usually be managed with supportive measures or medications prescribed by your healthcare provider.
  • Fatigue: Fatigue or weakness is a common side effect of Soranib (Sorafenib). It is important to get adequate rest and consult your healthcare provider if fatigue becomes severe or persistent.
  • Skin Reactions: Some patients may experience skin reactions such as hand-foot skin reaction (redness, swelling, or pain on the palms of the hands or soles of the feet), rash, dry skin, or hair thinning. Inform your healthcare provider about any skin changes, as they can provide guidance on management strategies.
  • Hypertension: Soranib/Nexavar can cause an increase in blood pressure. Regular monitoring of blood pressure is important, and if hypertension develops, appropriate management measures may be initiated.
  • Bleeding: Soranib can increase the risk of bleeding, which may manifest as nosebleeds, bruising, or prolonged bleeding from minor cuts. It is important to notify your healthcare provider if you experience any unusual bleeding episodes.
  • Cardiac Effects: Soranib may cause cardiac side effects, including heart rhythm abnormalities or heart failure. Regular cardiac monitoring and evaluation of heart function are typically conducted during treatment.
  • Hepatic Dysfunction: Soranib can affect liver function, leading to elevated liver enzymes. Regular liver function tests are recommended, and any signs of liver dysfunction should be reported to your healthcare provider.

Frequently Asked Queries About Sorafenib Tablet (Soranib)

FAQ: Can Sorafenib Tablet (Soranib) be taken with other medications for cancer treatment?

Answer: It is important to inform your healthcare provider about all medications you are taking, including other cancer treatments. Certain medications may interact with Soranib, potentially affecting its effectiveness or increasing the risk of side effects. Your healthcare provider will evaluate potential drug interactions and recommend the best treatment approach for you.

FAQ: Can I consume alcohol while taking Sorafenib Tablet (Soranib)?

Answer: It is generally advisable to avoid alcohol consumption while on Soranib treatment. Alcohol can increase the risk of liver damage, which is already a potential side effect of Soranib. Additionally, alcohol can interact with the medication and affect its effectiveness. It is best to consult with your healthcare provider regarding alcohol consumption during your treatment.

FAQ: What should I do if I miss a dose of Sorafenib Tablet (Soranib)?

Answer: If you miss a dose, take it as soon as you remember, unless it is close to the time for your next scheduled dose. Do not take a double dose to make up for the missed one. Simply resume your regular dosing schedule. If you have any concerns or questions about missed doses, consult your healthcare provider for guidance.

FAQ: Can Sorafenib Tablet (Soranib/Nexavar) be taken on an empty stomach?

Answer: Soranib can be taken with or without food. However, if you experience stomach upset or gastrointestinal side effects such as nausea or vomiting, taking the medication with food may help alleviate these symptoms. It is best to follow the instructions provided by your healthcare provider regarding the administration of Soranib.

FAQ: Are there any specific dietary restrictions while on Sorafenib Tablet (Soranib)?

Answer: There are no specific dietary restrictions associated with Soranib. However, maintaining a healthy and balanced diet is important for overall well-being and can support your body during cancer treatment. It is advisable to discuss any dietary concerns or specific recommendations with a registered dietitian or your healthcare provider for personalized guidance.

Some notable drug interactions with Soranib Tablet (Sorafenib) include:

It is important to inform your healthcare provider about all medications, supplements, and herbal products you are taking, as they may interact with Soranib. 

  • Blood Thinners: Sorafenib/Nexavar may increase the risk of bleeding when used concurrently with blood-thinning medications such as warfarin. Close monitoring of blood clotting parameters is advised.
  • Anticonvulsants: Certain anticonvulsant medications, such as phenytoin and carbamazepine, may decrease the effectiveness of Soranib. Your healthcare provider may need to adjust the dosage of Soranib or consider alternative treatment options.
  • St. John's Wort: The herbal supplement St. John's Wort can reduce the effectiveness of Soranib. It is important to avoid using this supplement while on Soranib treatment.
  • Grapefruit Juice: Grapefruit juice may increase the levels of Soranib (Sorafenib) in the body, leading to an increased risk of side effects. It is advisable to avoid consuming grapefruit or grapefruit juice while taking Soranib.
More Information Demo
Manufacturer : Cipla Pharma, India
Equivalent Brand : Nexavar
Generic Search : Sorafenib