Endogest SR Tablet (Progesterone (Natural Micronized)

Natural micronized progesterone, such as Prometrium and Endogest SR Tablet, is prescribed for various medical conditions. Progesterone is a vital hormone in the female reproductive system, playing a crucial role in regulating menstruation and supporting pregnancy.

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Endogest 200 Mg SR Tablet (Progesterone (Natural Micronized) 200mg)

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30 Tablet/s $44.40
60 Tablet/s $89.00
90 Tablet/s $133.50

Endogest 300 Mg SR Tablet (Progesterone (Natural Micronized) 300mg)

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30 Tablet/s $60.00
60 Tablet/s $120.00
90 Tablet/s $181.00

Endogest 400 Mg SR Tablet (Progesterone (Natural Micronized) 400mg)

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30 Tablet/s $75.00
60 Tablet/s $150.00
90 Tablet/s $225.00

What is Endogest SR Tablet (Progesterone (Natural Micronized)?

Progesterone is a vital hormone in the female reproductive system, playing a crucial role in regulating menstruation and supporting pregnancy. Natural micronized progesterone tablets, such as Endogest SR and Prometrium, are prescribed for various medical conditions. It plays a pivotal role in Women's Care, especially in the management of Hormonal Diseases. This medication is often prescribed to address various gynecological and hormonal disorders. It helps maintain a healthy hormonal balance, making it essential for conditions like irregular menstrual cycles, hormonal imbalances, and polycystic ovarian syndrome (PCOS). By providing a steady and sustained release of progesterone, Endogest SR Tablet contributes to women's overall well-being and is a valuable tool in the management of hormonal diseases. However, it should be used under the supervision and prescription of a qualified healthcare provider to ensure its appropriate and effective usage. This comprehensive guide provides detailed information on the usage, dosage, potential side effects, precautions, and drug interactions associated with progesterone tablets.

Progesterone (Natural Micronized) Dosage Information:

Progesterone tablets are available in various strengths and formulations. The dosage depends on the specific medical condition being treated. Typically, the recommended dose ranges from 100 to 200 milligrams per day, administered orally or vaginally. Endogest SR 200 is a specific dosage strength of sustained-release progesterone tablets. It is frequently used in pregnancy to provide optimal progesterone levels for maintaining a healthy pregnancy.

Missed Dose:

If you miss a dose of progesterone, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.


Excessive progesterone intake can lead to symptoms such as dizziness, nausea, vomiting, and fatigue. In case of a suspected overdose, seek immediate medical attention. Overdose management may involve supportive care to alleviate symptoms.

Endogest SR for Pregnancy:

Endogest SR, a sustained-release progesterone formulation, is commonly prescribed during pregnancy. It helps maintain the uterine lining and supports a healthy pregnancy. This reduces the risk of miscarriage and preterm birth.

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Essential Safety Advice to Follow when Using Endogest SR Tablet (Progesterone (Natural Micronized) 

  • Progesterone tablets like Endogest SR should only be used during pregnancy and breastfeeding under the supervision of a healthcare provider. It is essential to discuss the potential benefits and risks with your doctor.
  • Inform your healthcare provider about any existing medical conditions, such as liver disease, blood clots, or a history of certain cancers, as they may affect the suitability of progesterone therapy.
  • Ensure that you are not allergic to any components of the progesterone tablet/Prometrium before using it. Consult with your healthcare provider if you have a history of allergies or adverse reactions to medications.
  • Progesterone tablets can interact with certain medications, including blood thinners and medications for seizures. Inform your healthcare provider about all medications you are taking to prevent potential drug interactions.
  • Regular monitoring by a healthcare provider is crucial when using progesterone tablets, especially during pregnancy. Follow-up appointments allow for adjustments in dosage and assessment of treatment effectiveness.

Progesterone Natural Micronized Tablets/Prometrium are prescribed for various medical indications, including:

  • Hormone Replacement Therapy (HRT): Progesterone tablets are commonly prescribed as part of Hormone Replacement Therapy for menopausal women. They help balance hormone levels, alleviate menopausal symptoms like hot flashes, and reduce the risk of uterine cancer when combined with estrogen.
  • Irregular Menstrual Cycles: Progesterone is sometimes prescribed to regulate menstrual cycles in cases of irregular periods. It can help establish a predictable menstrual pattern.
  • Amenorrhea: In cases of amenorrhea (absence of menstrual periods), progesterone may be given to induce a withdrawal bleed and maintain uterine health.
  • Infertility: Progesterone may be prescribed to support pregnancy in cases of Female Infertility or recurrent miscarriages. It helps maintain the uterine lining, making it more conducive for embryo implantation.
  • Endometrial Hyperplasia: Progesterone is used to treat endometrial hyperplasia, a condition characterized by the thickening of the uterine lining. It helps reduce the risk of developing endometrial cancer.
  • Premenstrual Syndrome (PMS): For some women, progesterone can alleviate symptoms of PMS, such as mood swings, bloating, and breast tenderness.
  • Assisted Reproductive Techniques (ART): Progesterone is commonly prescribed in fertility treatments like in vitro fertilization (IVF) to support the implantation of embryos.
  • Contraception: Progesterone-only pills, often referred to as the "mini-pill," are a form of contraception that relies on progesterone to prevent pregnancy.
  • .


A few of the subsequent impacts stemming from Endogest SR Tablet (Progesterone (Natural Micronized) 

Common Side Effects:

The use of progesterone tablets may lead to common side effects such as:
a. Breast tenderness.
b. Dizziness.
c. Headache.
d. Mood swings.
e. Fatigue.

Uncommon Side Effects:

In some cases, individuals may experience less common side effects, including:
a. Nausea and vomiting.
b. Weight changes.
c. Abdominal bloating.
d. Skin reactions.
e. Changes in libido.

Allergic Reactions:

Although rare, severe allergic reactions to progesterone tablets can occur. Symptoms may include itching, swelling, severe dizziness, and difficulty breathing. Seek immediate medical attention if any signs of an allergic reaction occur.


Frequently Asked Queries About Endogest SR Tablet (Progesterone (Natural Micronized) 

Q1. What Are the Alternatives to Progesterone Tablets/Prometrium for Hormone Replacement Therapy?

Alternative hormone replacement therapy options include estrogen-only medications and non-hormonal treatments. Consult your healthcare provider to determine the most suitable choice based on your specific needs and medical history.

Q2. Can Progesterone Tablets Be Used for Birth Control?

No, progesterone tablets are not intended for birth control. They are primarily used for hormone replacement therapy, pregnancy support, and other medical conditions. Consider contraceptive methods designed for birth control purposes.

Q3. Are Natural Micronized Progesterone Tablets Safe for Long-Term Use?

Long-term use of natural micronized progesterone tablets, under medical supervision, is generally safe for managing certain medical conditions. However, your healthcare provider will periodically assess the necessity and safety of continued use.

Q4. Is It Safe to Combine Progesterone Tablets with Herbal Supplements Like Vitex?

Combining progesterone tablets with herbal supplements should be done cautiously. Consult your healthcare provider before using herbal remedies, as some interactions may affect treatment efficacy or safety.

Q5. Can Progesterone Tablets Be Used During Menopause for Hot Flash Relief?

Progesterone tablets alone are not typically used for hot flash relief during menopause. Estrogen-based therapies are more commonly prescribed. Discuss your symptoms and treatment options with your healthcare provider to determine the most suitable approach.

Significant Drug Interactions that Require Attention For Endogest SR Tablet (Progesterone (Natural Micronized) 

  • Progesterone tablets may interact with blood thinners like warfarin, increasing the risk of bleeding. Close monitoring of blood clotting parameters is necessary if these medications are used together.
  • Some antiepileptic medications, such as phenytoin and carbamazepine, can reduce the effectiveness of progesterone. Dosage adjustments may be required if progesterone is used alongside these drugs.
  • Herbal supplements like St. John's Wort can potentially reduce the efficacy of progesterone therapy. Consult with your healthcare provider before using herbal remedies while taking progesterone tablets.
  • When progesterone tablets are used in combination with estrogen in hormone replacement therapy, they may influence the risk of certain health conditions. Discuss the risks and benefits of combination therapy with your healthcare provider.
  • Progesterone tablets can interact with immunosuppressive drugs, which may impact their effectiveness. Healthcare providers should carefully monitor patients using these medications together.
More Information Demo
Manufacturer : Cipla Pharma, India
Equivalent Brand : Prometrium
Generic Search : Progesterone (Natural Micronized)