Susten VT Tablet (Progesterone (Natural Micronized))
Susten VT 200 Tablet is a medication that is used to regulate and restore menstrual cycles in women who have experienced a cessation of periods. It contains natural micronized progesterone that plays a crucial role in controlling ovulation, which is the release of an egg from a woman's ovary, as well as in regulating menstruation.
Product Overview
Susten VT Tablet is a vaginal formulation containing Natural Micronized Progesterone, designed to support and supplement progesterone levels in the body. It is primarily used in reproductive medicine to aid in hormonal balance, particularly during assisted reproductive techniques (ART), luteal phase support, and conditions associated with progesterone deficiency.
The vaginal route allows targeted delivery with improved uterine bioavailability, making it an effective option in fertility and early pregnancy support protocols under medical supervision.
Mechanism Insights (How It Works)
- Endometrial Preparation
Progesterone transforms the uterine lining (endometrium) into a receptive state, supporting implantation of a fertilized egg. - Hormonal Support
It compensates for insufficient natural progesterone production, helping maintain a stable hormonal environment during the luteal phase or early pregnancy. - Pregnancy Maintenance Support
Progesterone reduces uterine contractions and supports conditions necessary for continuation of early pregnancy. - Localized Vaginal Absorption
Vaginal delivery enhances direct transport to the uterus (uterine first-pass effect), improving therapeutic efficiency.
Administration Guidelines
- Insert vaginally as directed by the physician
- Preferably used at a consistent time each day
- Maintain hygiene before and after insertion
- Do not discontinue abruptly without medical advice
- Follow prescribed duration strictly, especially in fertility cycles or early pregnancy support
Clinical Considerations
- Commonly used in IVF/ART protocols for luteal phase support
- May be prescribed in cases of progesterone deficiency or recurrent miscarriage risk (as determined by clinician)
- Vaginal route minimizes systemic side effects compared to oral progesterone in many cases
- Requires strict adherence to timing and dosage for optimal reproductive outcomes
- Should only be used under gynecological supervision
Precautions:
Susten VT (vaginal progesterone) should be used only under proper medical supervision to ensure safe and effective therapy. It is commonly prescribed for hormonal support, especially in early pregnancy or progesterone deficiency conditions.
General Precautions
- Use strictly as prescribed by a healthcare professional
- Do not self-medicate or change the dose without medical advice
- Follow the full prescribed duration even if symptoms improve
- Use vaginal tablets only as directed (correct timing and placement are important)
- Maintain proper genital hygiene during use
- Report any unusual vaginal irritation, discharge, or discomfort to your doctor
Hormonal & Medical Considerations
- Progesterone may cause side effects such as dizziness, breast tenderness, bloating, or mood changes
- Use cautiously in patients with:
- Hormone-sensitive conditions (e.g., breast or reproductive organ cancers)
- Unexplained vaginal bleeding
- Liver disorders (hormone metabolism may be affected)
- Regular monitoring may be advised during long-term hormonal therapy
- Avoid use with certain other hormonal medications unless prescribed together
Pregnancy & Breastfeeding
- Commonly prescribed and considered important for pregnancy support when indicated
- Should be used only under obstetric guidance
- Not to be started or stopped without a doctor’s advice during pregnancy
- Small amounts may pass into breast milk; consult a doctor before use while breastfeeding
Blood Clot & Cardiovascular Risk
- Use cautiously in individuals with a history of blood clots (DVT, stroke, pulmonary embolism)
- Report symptoms such as leg swelling, chest pain, or sudden shortness of breath immediately
- Risk may increase with combined hormonal therapy in some cases
Infection & Hygiene Measures
- Maintain good personal hygiene during vaginal use
- Wash hands before and after administration
- Avoid unprotected self-insertion in unhygienic conditions
- Do not share medication or applicators if provided
Usage
General Usage Information
Susten VT Tablet is a progesterone supplement used as part of hormone support therapy. It is commonly prescribed for conditions where progesterone levels need to be supported, such as in fertility treatments, luteal phase support, or to help maintain early pregnancy in selected cases. The effectiveness of the therapy depends on correct dosage, proper vaginal administration, and consistent use as directed by a healthcare professional.
Key Usage Points
✔ Use exactly as prescribed by your doctor
✔ Insert the tablet vaginally as directed (do not take orally unless specifically advised)
✔ Wash hands thoroughly before and after administration
✔ Preferably use at bedtime for better retention and absorption
✔ Do not skip doses to maintain stable hormone levels
✔ Complete the full prescribed course even if symptoms improve
Uses
Susten VT Tablet is commonly used in:
- Luteal phase support in infertility treatment
- Hormonal support in assisted reproductive techniques (e.g., IVF)
- Prevention of progesterone deficiency-related pregnancy complications (as advised by a doctor)
- Management of menstrual irregularities due to low progesterone levels
- Support in early pregnancy where prescribed
How to Use
- Insert the tablet gently into the vagina using clean hands or an applicator if provided
- Preferably use it while lying down, usually at bedtime
- Follow the exact dosage and schedule prescribed by your healthcare provider
- Do not swallow the tablet
- Maintain personal hygiene during the treatment period
- Continue usage for the duration recommended by your doctor, even if symptoms improve
Side Effects
General Safety Information
Susten VT (Progesterone – Natural Micronized) is generally well tolerated when used as prescribed, especially in vaginal tablet form. Side effects, if they occur, are usually mild and temporary and may vary depending on dosage, duration of use, and individual sensitivity.
Common Side Effects
✔ Vaginal irritation, itching, or discharge
✔ Breast tenderness or swelling
✔ Headache
✔ Bloating or abdominal discomfort
✔ Drowsiness or fatigue
✔ Mood changes (mild irritability or mood swings)
These effects are usually temporary and often reduce as the body adjusts to the medication.
Serious Side Effects (Rare but Important)
âš Seek medical attention if you experience:
- Signs of allergic reaction (rash, itching, swelling, severe dizziness)
- Unusual vaginal bleeding or spotting
- Severe abdominal pain
- Chest pain or shortness of breath
- Severe headache or vision changes
- Signs of blood clot (pain/swelling in leg, sudden breathlessness)
Risk Factors & Monitoring
Higher caution in patients with:
- Liver disease
- History of blood clots or cardiovascular conditions
- Hormone-sensitive conditions (as advised by a doctor)
Long-term use may require periodic medical evaluation depending on the treatment purpose (e.g., luteal support, infertility treatment, or hormone therapy).
FAQs
Interactions
General Interaction Overview
Susten VT (natural micronized progesterone) may interact with medicines that affect liver enzymes responsible for its metabolism or with drugs whose effects are influenced by hormonal changes. These interactions can alter progesterone levels in the body or change how other medicines work, so it is important to inform your healthcare provider about all medications you are using.
Commonly Reported Interactions
- Enzyme-inducing medicines (may reduce effectiveness):
Drugs such as rifampicin, carbamazepine, phenytoin, and phenobarbital can increase the breakdown of progesterone, lowering its effectiveness. - Herbal products like St. John’s Wort:
May reduce progesterone levels by increasing metabolic activity in the liver. - Antifungal and antiviral medicines (may increase hormone levels):
Drugs like ketoconazole or certain HIV protease inhibitors can slow metabolism and increase progesterone concentration, potentially raising side effect risk. - Anticoagulants (e.g., warfarin):
Progesterone may alter the response to blood thinners, requiring closer monitoring of clotting levels.
| Manufacturer | : | Sun Pharma, India |
| Equivalent Brand | : | Prometrium |
| Generic Search | : | Progesterone (Natural Micronized) |





















