Glynase-MF Tablet (Glipizide + Metformin)

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Buy Glynase-MF Tablet (Glipizide + Metformin), Glipizide + Metformin tablets, commonly sold under the brand names Glynase-MF and Metaglip, is a combination medication used to manage type 2 diabetes mellitus.

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Glynase-MF Tablet (Glipizide (5mg) + Metformin (500mg))

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30 Tablet/s $3.00
60 Tablet/s $7.00
90 Tablet/s $10.00

Introduction of Glynase-MF Tablet (Glipizide + Metformin)

Glipizide + Metformin tablets, commonly sold under the brand names Glynase-MF and Metaglip, are a combination medication used to manage Type 2 Diabetes mellitus. This drug amalgamates two distinct mechanisms of action, with Glipizide enhancing insulin secretion and Metformin improving insulin sensitivity. The synergistic effect of these components aids in controlling blood sugar levels and achieving glycemic control. In this comprehensive guide, we delve into various aspects of Glipizide + Metformin tablets, including dosage information, uses, potential side effects, precautions, and drug interactions.

Metaglip/Glipizide + Metformin Dosage Information:

Initial Dosage: The typical starting dose of Glipizide + Metformin tablets varies based on individual patient characteristics. Generally, a common initiation could be one tablet taken orally once daily during the morning meal.
Titration: Dosage adjustments should be made under the guidance of a healthcare provider to achieve optimal glycemic control. This may involve increasing the dosage gradually, usually not exceeding more than 10 mg of Glipizide and 2000 mg of Metformin daily.
Renal Function Consideration: Given Metformin's potential impact on renal function, adjustments are necessary for patients with compromised kidney function. Regular monitoring of renal function and dosage adaptation is crucial to prevent the accumulation of Metformin and its associated risks.

Missed Dose:

If a dose is missed, it's recommended not to double the next dose to make up for it. The missed dose should be skipped, and the regular dosing schedule should be resumed. Doubling the dose can increase the risk of hypoglycemia and other adverse effects.

Overdosing on Glipizide + Metformin tablets can lead to severe hypoglycemia (low blood sugar) and potentially life-threatening complications. Symptoms of overdose include excessive sweating, confusion, tremors, rapid heartbeat, and fainting. In case of an overdose, medical attention should be sought immediately.

Glipizide Metformin Prescription:

A prescription from a healthcare professional is typically required to obtain Glipizide Metformin tablets. This is because the medication's dosage and usage need to be tailored to individual health conditions and needs.

Managing Diabetes with Glipizide Metformin:

Glipizide Metformin tablets play a crucial role in managing type 2 diabetes. Their dual action helps regulate blood sugar levels effectively. However, it's essential to follow medical advice, maintain a healthy lifestyle, and monitor your condition regularly for optimal diabetes management.

Glipizide Metformin Tablet Availability:

You might find Glipizide Metformin tablets available at, a reputable online pharmacy. Always ensure the authenticity of the product and verify the source before making a purchase. Consulting a healthcare provider before starting or altering any medication regimen is recommended.

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Essential Safety Advice to Follow when Using Metaglip/Glynase-MF Tablet (Glipizide + Metformin)

  • Renal Function: Since Metformin is eliminated through the kidneys, patients with renal impairment should be closely monitored and might require dosage adjustments or discontinuation.
  • Hepatic Impairment: Glipizide is metabolized in the liver. Caution should be exercised in patients with hepatic impairment, and adjustments in dosage or medication selection might be necessary.
  • Hypoglycemia Risk: Elderly patients are particularly susceptible to hypoglycemia. Regular monitoring of blood glucose levels and appropriate dosing are crucial.
  • Surgery and Illness: During surgical procedures or illnesses, Glipizide + Metformin tablets might need to be temporarily discontinued, and alternative methods of glycemic control should be considered.
  • Contrast Dye: If a patient on Glipizide + Metformin tablets requires a procedure involving contrast dye, it's important to temporarily discontinue the medication to prevent potential kidney complications.

Some of the specific indications for Metaglip/Glynase-MF Tablet (Glipizide + Metformin) include

  • Type 2 Diabetes Management: Glipizide + Metformin tablets are primarily prescribed to manage type 2 diabetes. Glipizide stimulates the pancreas to release more insulin, while Metformin improves the body's response to insulin, thus aiding in blood sugar regulation.
  • Glycemic Control: The combination of Glipizide and Metformin addresses different facets of glucose regulation, providing comprehensive glycemic control that can help lower HbA1c levels and reduce the risk of diabetic complications.
  • Adjunct to Lifestyle Modifications: These tablets are often prescribed alongside dietary and lifestyle modifications to enhance the overall effectiveness of Diabetes management.
  • Dual Mechanism of Action: The combination leverages the strengths of both Glipizide and Metformin, offering a synergistic effect that targets multiple pathways contributing to hyperglycemia.
  • Long-term Management: Glipizide + Metformin tablets are suitable for long-term use and can be integrated into a broader diabetes management strategy.

Buy Glipizide Metformin Tablet:

At, you can conveniently purchase Glipizide Metformin tablets. Browse the website, add the medication to your cart, and proceed to checkout. Ensure to provide accurate prescription details as required. offers a user-friendly platform to access genuine medications, making your purchasing process reliable and hassle-free.

Some of the Secondary Effects of Glynase-MF Tablet (Glipizide + Metformin)

  • Hypoglycemia: Glipizide + Metformin tablets can lead to low blood sugar levels, causing symptoms like shakiness, sweating, dizziness, and confusion. Regular monitoring and proper meal planning can help mitigate this risk.
  • Gastrointestinal Distress: Metformin is known to cause gastrointestinal side effects, including nausea, diarrhea, and abdominal discomfort. These effects are usually transient and can be managed by taking the medication with meals.
  • Lactic Acidosis: Although rare, Metformin can trigger a serious condition called lactic acidosis, characterized by muscle pain, weakness, and labored breathing. This risk increases in patients with kidney or liver issues.
  • Weight Gain/Loss: Glipizide may lead to weight gain, while Metformin is associated with weight loss. The combination's impact on weight can vary among individuals.
  • Allergic Reactions: Some individuals might experience allergic reactions like rash, itching, swelling, severe dizziness, or trouble breathing. These symptoms require immediate medical attention.

Answers to Common Inquiries about Glipizide + Metformin Tablets (Glynase-MF, Metaglip)

Q1. Can I adjust my Glipizide + Metformin dosage on my own?

No, dosage adjustments should be overseen by a healthcare provider. Altering doses without medical guidance can lead to adverse effects, including hypoglycemia or poor glycemic control.

Q2. Is it safe to use Glipizide + Metformin during pregnancy?

Consult your doctor. While Metformin is generally considered safer during pregnancy, Glipizide's use might be reconsidered. Your healthcare provider can evaluate the risks and benefits to determine the most appropriate treatment plan.

Q3. Can I consume alcohol while taking these tablets?

It's advised to limit alcohol intake. Alcohol can intensify the risk of hypoglycemia and interfere with the medication's efficacy, potentially undermining your diabetes management efforts.

Q4. Are Glipizide + Metformin tablets suitable for elderly patients?

Yes, they can be used in older adults, but caution is needed due to the increased risk of hypoglycemia. Regular monitoring of blood sugar levels and individualized dosing adjustments are essential.

Q5. What should I do if I experience persistent gastrointestinal side effects?

If nausea, diarrhea, or abdominal discomfort persist, consult your doctor. They can provide guidance on managing these side effects or may consider adjusting the medication to improve your tolerance.

Combining different drugs can lead to Adverse Effects Glynase-MF Tablet (Glipizide + Metformin)

  • Beta-Blockers: Certain beta-blockers can mask the symptoms of hypoglycemia, making it challenging to recognize low blood sugar levels while on Glipizide.
  • ACE Inhibitors and ARBs: Concomitant use of Angiotensin-Converting Enzyme (ACE) inhibitors or Angiotensin II Receptor Blockers (ARBs) with Glipizide + Metformin tablets can increase the risk of hypoglycemia.
  • Cimetidine: Cimetidine can interfere with Metformin's elimination, potentially leading to higher Metformin levels and an increased risk of side effects.
  • Iodinated Contrast: The use of iodinated contrast agents for imaging studies in patients taking Metformin can increase the risk of lactic acidosis, necessitating temporary discontinuation.
  • Alcohol: Alcohol consumption can potentiate the hypoglycemic effects of Glipizide and increase the risk of adverse reactions. Limiting alcohol intake is advisable.
More Information Demo
Manufacturer:USV Pharma, India
Equivalent Brand:Metaglip
Generic Search:Glipizide + Metformin