Daonil-M Tablet SR (Glibenclamide + Metformin)

Buy Daonil-M Tablet SR is a combination medication that is commonly prescribed for the management of type 2 diabetes mellitus. This tablet combines two active ingredients: Glibenclamide and Metformin.

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Daonil-M Tablet SR (Glibenclamide (5mg) + Metformin (500mg))

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30 Tablet/s $6.20
60 Tablet/s $12.40
90 Tablet/s $19.00

Daonil-M Tablet SR (Glibenclamide + Metformin) for Diabetes

Daonil-M Tablet SR is a combination medication that is commonly prescribed for the management of type 2 diabetes mellitus. This tablet combines two active ingredients: Glibenclamide and Metformin. Glibenclamide belongs to the sulfonylurea class of drugs and helps to lower blood sugar levels by stimulating the pancreas to release more insulin. Metformin, on the other hand, is a biguanide that improves insulin sensitivity and reduces the liver's glucose production. This combination provides a synergistic approach to controlling blood sugar levels in individuals with Type 2 Diabetes.  The Metformin Glibenclamide combination, as found in Daonil-M Tablet SR, offers a dual-action approach to managing type 2 diabetes. Daonil-M Tablet SR is often prescribed alongside lifestyle modifications, including a balanced diet and regular exercise, to achieve optimal Diabetes management.

Daonil-M Tablet SR Dosage Information:

Standard Dosage: The typical initial dose of Daonil-M Tablet SR is one tablet once a day, preferably with a meal. The dose may be adjusted by your healthcare provider based on your blood sugar levels and response to treatment. The tablet should be swallowed whole without crushing or chewing.

Missed Dose: If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as it may lead to an increased risk of hypoglycemia (low blood sugar).

Overdose: Taking more than the prescribed dose of Daonil-M Tablet SR can lead to hypoglycemia, which is characterized by symptoms such as excessive sweating, trembling, confusion, dizziness, and fainting. In case of an overdose, seek medical attention immediately. It's important to have a source of fast-acting glucose, such as glucose tablets or sugary beverages, on hand to raise your blood sugar quickly.

Alternatives to Daonil-M Tablet SR:

For those seeking alternatives to Daonil-M Tablet SR, there are various options available. Your healthcare provider can consider prescribing different oral antidiabetic medications, such as other sulfonylureas, biguanides, or even newer classes like DPP-4 inhibitors or SGLT-2 inhibitors, based on your individual medical history and treatment goals. Explore the wide range of alternatives available for Type 2 Diabetes.

Sicriptin Tablet (Bromocriptine Mesylate) 

Glinate Tablet (Nateglinide)

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When Using Daonil-M Tablet SR (Glibenclamide + Metformin), It Is Important To Take Certain Precautions

  • Hypoglycemia Awareness: It's crucial to be aware of the symptoms of hypoglycemia and carry a source of glucose (such as glucose tablets) with you at all times. Inform your close contacts about your condition in case you need assistance during a hypoglycemic episode.
  • Kidney Function: Before starting Daonil-M Tablet SR, your kidney function should be assessed, as Metformin is excreted through the kidneys. Impaired kidney function can increase the risk of Metformin accumulation and lactic acidosis.
  • Liver Function: Individuals with liver disease should use this medication cautiously, as both Glibenclamide and Metformin are metabolized in the liver. Altered liver function can affect drug metabolism and increase the risk of side effects.
  • Allergic History: If you have a history of allergies to sulfonylureas, Metformin, or any other components of the medication, inform your healthcare provider before starting treatment.
  • Surgery and Medical Procedures: If you're scheduled for surgery or any medical procedure, it's important to inform the medical team about your Daonil-M Tablet SR use, as the medication might need to be temporarily discontinued to prevent hypoglycemia during the perioperative period.

Some of the specific indications for Daonil-M Tablet SR (Glibenclamide + Metformin) include

  • Type 2 Diabetes Management: Daonil-M Tablet SR is primarily used to manage type 2 diabetes mellitus. It helps lower blood sugar levels by increasing insulin release from the pancreas and improving insulin sensitivity in peripheral tissues.
  • Combination Therapy: This medication is particularly beneficial for individuals who require dual therapy to achieve better glycemic control. The combined action of Glibenclamide and Metformin addresses multiple pathways involved in glucose regulation.
  • Insulin Sensitization: Metformin in the formulation not only helps lower blood sugar levels but also enhances the body's response to insulin. This is especially important for individuals with insulin resistance, a common feature of type 2 diabetes.
  • Long-Lasting Effect: The sustained-release (SR) formulation of Daonil-M Tablet ensures a gradual and prolonged release of the active ingredients, leading to sustained blood sugar control throughout the day.
  • Lifestyle Support: Daonil-M Tablet SR is often prescribed alongside lifestyle modifications, including a balanced diet and regular exercise, to achieve optimal diabetes management.

Crucial Side Effects to Be Observed When Using Daonil-M Tablet SR (Glibenclamide + Metformin)

  • Hypoglycemia: One of the potential side effects of Daonil-M Tablet SR is hypoglycemia, especially if the dose is too high or if you skip meals. Symptoms of hypoglycemia include sweating, palpitations, anxiety, confusion, and weakness.
  • Gastrointestinal Distress: Metformin can cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and abdominal discomfort. Starting with a lower dose and gradually increasing it can help mitigate these effects.
  • Weight Gain: Glibenclamide, as a sulfonylurea, might be associated with weight gain due to its mechanism of action in increasing insulin secretion.
  • Lactic Acidosis: Although rare, Metformin can lead to a serious condition called lactic acidosis, which is characterized by symptoms like muscle pain, weakness, difficulty breathing, and irregular heartbeat. This risk is higher in individuals with kidney or liver issues.
  • Allergic Reactions: Some individuals may experience allergic reactions to the medication, which could manifest as skin rashes, itching, swelling, or difficulty breathing. Seek medical help if you notice any of these symptoms.

Answers to Common Inquiries about Daonil-M Tablet SR (Glibenclamide + Metformin) for Diabetes:

Q1. Can I take Daonil-M Tablet SR on an empty stomach?

It's recommended to take Daonil-M Tablet SR with a meal to reduce the risk of gastrointestinal discomfort. Consuming it with food also helps optimize its absorption and minimize the chances of stomach upset.

Q2. Is Daonil-M Tablet SR suitable for elderly individuals with diabetes?

Yes, Daonil-M Tablet SR can be used in elderly individuals with type 2 diabetes. However, dosage adjustments might be necessary, and close monitoring of blood sugar levels and potential side effects is important due to age-related physiological changes.

Q3. Can Daonil-M Tablet SR cause vitamin B12 deficiency?

While Metformin has been associated with a potential risk of vitamin B12 deficiency over prolonged use, Daonil-M Tablet SR's combination with Metformin may exacerbate this risk. Regular monitoring of vitamin B12 levels and supplementation, if necessary, can help mitigate this concern.

Q4. Can I engage in physical activities while taking Daonil-M Tablet SR?

Engaging in regular physical activities is encouraged for individuals with diabetes. However, because Daonil-M Tablet SR can lower blood sugar levels, it's important to monitor your glucose levels closely before, during, and after exercise to prevent hypoglycemia. Adjustments in dosage might be needed.

Q5. How does Daonil-M Tablet SR differ from insulin therapy?

Daonil-M Tablet SR is an oral medication that combines Glibenclamide and Metformin to manage type 2 diabetes. Insulin therapy involves injecting insulin to regulate blood sugar. While both approaches aim to control glucose levels, the choice depends on individual factors, such as disease progression, patient preferences, and medical considerations.

Q6. Where to Buy Glibenclamide Metformin?

You can find Glibenclamide Metformin combinations, including products like Daonil-M Tablet SR, on our website 1mgstore.com. Our platform provides a convenient way to purchase your medications online. However, it's important to consult your healthcare provider before starting any new medication to ensure it's the right choice for your diabetes management.

Significant Drug Interactions that Require Attention For Daonil-M Tablet SR (Glibenclamide + Metformin)

  • Hypoglycemia Risk: Combining Daonil-M Tablet SR with other medications that lower blood sugar, such as insulin or other oral antidiabetic drugs, increases the risk of hypoglycemia. Regular monitoring of blood sugar levels is essential.
  • Beta-Blockers: Certain beta-blocker medications used for heart conditions can mask the symptoms of hypoglycemia, making it difficult to recognize low blood sugar levels. Close monitoring is necessary in such cases.
  • Diuretics: Some diuretics can reduce the effectiveness of Glibenclamide, potentially leading to elevated blood sugar levels. Your healthcare provider might need to adjust your dosage accordingly.
  • Interactions with Alcohol: Alcohol consumption can potentiate the hypoglycemic effects of Daonil-M Tablet SR and increase the risk of adverse reactions. Limit alcohol intake and discuss its use with your healthcare provider.
  • Cimetidine and Ranitidine: These medications, used to treat gastrointestinal issues, can interact with Glibenclamide, affecting its metabolism and leading to increased blood levels of the drug.
More Information Demo
Manufacturer : Emcure Pharma, India
Equivalent Brand : Daonil-M
Generic Search : Glibenclamide + Metformin